Results 21 to 30 of about 18,317 (173)

Kaempferol Addition Increases the Antimalarial Activity of Artesunate in Experimental Mice

Journal of Tropical Medicine, 2020
Kaempferol (KMF) is a member of flavonol widely found in tea, broccoli, apples, strawberries, and beans. It has been demonstrated to present several pharmacological properties with potent antimalarial activity against Plasmodium berghei-infected mice ...
Sakaewan Ounjaijean, Nattida Benjasak, Suchanan Sae-lao, Voravuth Somsak   +3 more
doaj   +1 more source

Synergistic Antimalarial Activity of Alpha-Mangostin Chitosan Alginate Nanoparticles with Chloroquine in Mice Infected with Plasmodium berghei: The Potential of a New Antimalarial Drug Combination [PDF]

Iranian Journal of Medical Sciences
Background: Malaria drug resistance is one of the leading causes of malaria-related morbidity and mortality worldwide. Alpha-mangostin exhibits antimalarial and antioxidant activity in vitro.
Susy Tjahjani, Faizal Hermanto, Muchtaridi Muchtaridi, Diah Lia Aulifa, Fahmi Ahsanul Haq   +4 more
doaj   +1 more source

The new algorithm for calculation of median lethal dose (LD50) and effective dose fifty (ED50) of Micrarus fulvius venom and anti-venom in mice

International Journal of Veterinary Science and Medicine, 2016
One million people throughout the world are bitten yearly by poisonous snakes. Of this, one-tenth died and three-tenth suffer some forms of disabilities.
Saganuwan Alhaji Saganuwan
doaj   +1 more source

Progress report on new epilepsy treatments: A summary of the Eighteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XVIII). II. Treatments in more advanced clinical development

Epilepsia, EarlyView.
Abstract This article summarizes data for 13 investigational treatments for which at least preliminary seizure outcome data in patients with epilepsy were reported at the Eighteenth Eilat Conference on New Antiepileptic Drugs and Devices held in Madrid, Spain, on May 3–6, 2026.
Meir Bialer, Cecilie Johannessen Landmark, Matthias J. Koepp, Emilio Perucca, Piero Perucca, Torbjörn Tomson, H. Steve White, Elaine Wirrell   +7 more
wiley   +1 more source

A Study Investigating the Synergistic Analgesic Effects of Nefopam and Medetomidine in a Multimodal Pain Management Approach in Mice [PDF]

Journal of Applied Veterinary Sciences
This study explored the type of analgesic interaction between nefopam and medetomidine and evaluated their safety profiles in a mouse model as no previous studies had examined their pharmacological interaction at the antinociceptive level. Adult male and
Hazem Khalil, Gada Faris
doaj   +1 more source

ارزیابی تحمل ارقام گندم و جو به کاربرد علفکش متری بیوزین [PDF]

پژوهشهای زراعی ایران, 2013
به منظور ارزیابی حساسیت ارقام جو وگندم به کاربرد علف کش متری بیوزین، آزمایشی به صورت فاکتوریل در قالب طرح کاملا تصادفی در 3 تکرار در گلخانه تحقیقاتی دانشکده کشاورزی دانشگاه فردوسی مشهد انجام شد. تیمارهای آزمایش شامل ارقام گندم (بک کراس روشن، کراس اروند،
ابراهیم ایزدی دربندی, علی اصغر چیت بند, عباس عباسیان, مجید حیدری   +3 more
doaj   +1 more source

Antiseizure potency and neurotoxicity of the enantiomers of fenfluramine and norfenfluramine in rats and correlations with their concentrations in plasma and brain

Epilepsia, EarlyView.
Abstract Objective Based on the evidence that fenfluramine‐induced anorexia, weight loss, and cardiovascular toxicity are primarily mediated by the d‐enantiomers of fenfluramine and its metabolite norfenfluramine, we investigated pharmacokinetic/pharmacodynamic correlations for the active enantiomers of fenfluramine and norfenfluramine in the rat ...
Yara Sheeni, Dinorah Barasch, Tawfeeq Shekh‐Ahmad, Emilio Perucca, Meir Bialer   +4 more
wiley   +1 more source

Effects of elevated CO2 and temperature on cocklebur (Xanthium strumarium L.) and its herbicide response

Pest Management Science, EarlyView.
Elevated CO2 promotes the growth of Xanthium strumarium while increasing its susceptibility to the systemic herbicide trifloxysulfuron‐sodium. The efficacy of the soil‐active herbicide fluometuron remains unaffected by changes in CO2 concentration and temperature.
Islam Emrah Suer, Nihat Tursun
wiley   +1 more source

Minimum effective dose of intrathecal hyperbaric bupivacaine for cesarean section with and without prophylactic norepinephrine infusion: Randomized triple-blinded trial

Journal of Anaesthesiology Clinical Pharmacology
Background and Aims: Vasopressor usage can affect the rostral spread of intrathecal drug and, hence, its requirement during cesarean delivery. Although a decreased spread is evidenced with phenylephrine, there is no data for norepinephrine usage.
Asha Tyagi, Monika Mathur, Rashmi Salhotra, Rajesh S. Rautela   +3 more
doaj   +1 more source

Experimental evidence refuting the assumption of phosphorus-31 nuclear-spin entanglement-mediated consciousness [PDF]

Journal of Integrative Neuroscience, 2020
Phosphorus-31 nuclear-spin entanglements within Ca9(PO4)6 molecules (Posner molecules) have been proposed to be central for neural processing. However, this has yet to be proven experimentally.
Rong Chen, Na Li, Hao Qian, Rui-Han Zhao, Shi-Hai Zhang   +4 more
doaj   +1 more source