Results 1 to 10 of about 8,368,619 (264)

Median effective dose (ED50) of esketamine combined with propofol for children to inhibit response of gastroscope insertion [PDF]

BMC Anesthesiology, 2023
Background Propofol is the most commonly used drug for procedural sedation during gastroscopy. However, independent use of propofol can lead to increased dosage and additional side effects.
Ming Su, Yichao Zhu, Shupeng Liu, Lijuan Song, Jiangtao Qu, Yong Zhang, Quanyi Zhang   +6 more
doaj   +3 more sources

Median effective dose of esketamine for intranasal premedication in children with congenital heart disease [PDF]

BMC Anesthesiology, 2023
Background Esketamine is commonly used as a premedication for its sedation effect. However, the proper dosage for intranasal use in children with congenital heart disease (CHD) has not been determined.
Jiajia Huang, Daoqing Liu, Jie Bai, Hongbin Gu   +3 more
doaj   +3 more sources

The Effect of Dezocine on the Median Effective Dose of Sufentanil-Induced Respiratory Depression in Patients Undergoing Spinal Anesthesia Combined with Low-Dose Dexmedetomidine [PDF]

Drug Design, Development and Therapy, 2023
Yong-Kang Gui,1,2,* Xiao-Hui Zeng,1,2,* Rui Xiao,3 Wen-Feng Xi,1– 3 Dan Zhang,1– 3 Yang Liu,1,2 Si-Hui Zhu,1,2 Xin Da,1,2 De-Wen Shi,1,2 Xu-Dong Hu,1,2 Guang-Hong Xu1,2 1Department of Anesthesiology, the First Affiliated Hospital of Anhui Medical
Gui YK, Zeng XH, Xiao R, Xi WF, Zhang D, Liu Y, Zhu SH, Da X, Shi DW, Hu XD, Xu GH   +10 more
doaj   +3 more sources

Determination of the median effective dose of sufentanil combined with remimazolam in inhibiting tracheal intubation response [PDF]

Scientific Reports
To determine the median effective dose (ED50) and 95% effective dose (ED95) of sufentanil combined with remimazolam for inhibiting the tracheal intubation response in patients undergoing general anesthesia and to evaluate the hemodynamic stability and ...
Lin Feng, Liang Zeng, Xuelei Zhou, Yiping Guo, Xianchun Liu, Longyi Zhang, Ting Zhang, Linji Li, Li Zhao   +8 more
doaj   +3 more sources

The Median Effective Dose and Bispectral Index of Remimazolam Tosilate for Anesthesia Induction in Elderly Patients: An Up-and-Down Sequential Allocation Trial [PDF]

Clinical Interventions in Aging, 2022
Miao Liu,1– 3 Yuan Sun,1– 3 Lingxue Zhou,1– 3 Kunpeng Feng,1– 3 Tianlong Wang,1– 3 Xuexin Feng1– 3 1Department of Anesthesiology, Capital Medical University Xuanwu Hospital, Beijing, People’s Republic of China; 2Center for Sleep and Consciousness ...
Liu M, Sun Y, Zhou L, Feng K, Tianlong Wang, Feng X   +5 more
doaj   +3 more sources

Median Effective Dose of Dexmedetomidine Inducing Bradycardia in Elderly Patients Determined by Up-and-Down Sequential Allocation Method. [PDF]

Int J Med Sci, 2022
Purpose: When dexmedetomidine is used in elderly patients, high incidence of bradycardia is reported. Given age-related physiological changes in this population, it is necessary to know the safety margin between the loading dose of dexmedetomidine and ...
Yang H, Fu Y, Deng F, Shao Y, Lu YG, Song JC.   +5 more
europepmc   +2 more sources

Determination of the Median Effective Dose (ED50) of Ciprofol for Successful Sedation in Pediatric Patients During General Anesthesia Induction. [PDF]

Drug Des Devel Ther
Purpose To determine the median effective dose (ED50) and 90% effective dose (ED90) of ciprofol for successful sedation during general anesthesia induction in pediatric patients, optimize dosing regimens, and provide reference evidence for clinical ...
Nie P, Wu D, Du C, Wang X, Zhang H, Xiao H.   +5 more
europepmc   +2 more sources

Median effective dose of remimazolam combined with sufentanil for inhibiting laryngeal mask airway insertion responses in children of different ages. [PDF]

Front Pharmacol
Introduction We determined the median effective dose and 95% confidence interval (CI) of remimazolam required to inhibit laryngeal mask airway (LMA) insertion reactions combined with sufentanil 0.3 μg/kg in pediatric anesthesia.
Li H, Wang J, Wei R, Jiang Y.
europepmc   +2 more sources

Median Effective Dose of Remifentanil for the Prevention of Pain Caused by the Injection of Rocuronium: An Age-Stratified Study [PDF]

Pain and Therapy, 2023
Introduction Rocuronium intravenous pain is common in induction of general anesthesia. The aim of our study was to determine the median effective dose (ED50) of prophylactic intravenous remifentanil for the prevention of rocuronium injection pain and to ...
Shiting Yan, Hao Wu, Yanlong Yu, Ning Li, Leyang Yu, Ying Wang, Hu Li, Dongsheng Zhang, Zhuan Zhang   +8 more
doaj   +2 more sources

The median effective dose of ciprofol combined with a low-dose sufentanil for gastroscopy in obese or nonobese patients: a dose-finding study using Dixon's up-and-down method. [PDF]

Front Pharmacol
Objectives Understanding the different pharmacodynamic responses to narcotics in patients with or without obesity is particularly important for the safety of gastroscopy sedation. This study aimed to determine the median effective dose (ED50) of ciprofol
Zhao J, Zhang Y, Su G, Wang S, Zhang X, Wang G, Chen G.   +6 more
europepmc   +2 more sources