Results 21 to 30 of about 452,355 (274)

The Median Effective Dose of Intrathecal Hyperbaric Bupivacaine for Cesarean Section at Moderately High-Altitude [PDF]

Drug Design, Development and Therapy
Chen Yang,1,2,* Wangjun Dong,2,* Jianbo Luo,2 Mengzhao Ma,2 Yeyue Gao,2 Lijie Ni,2 Huixing Liu,2 Chengjun Cha,2 Yangli Xiao,2 Shaoqiang Huang1 1Department of Anesthesia, Obstetrics & Gynecology Hospital, Fudan University, Shanghai, People’s ...
Yang C, Dong W, Luo J, Ma M, Gao Y, Ni L, Liu H, Cha C, Xiao Y, Huang S   +9 more
doaj   +2 more sources

The Median Effective Dose of Ciprofol Combined with Sufentanil for Inhibiting Responses to Gastroscope Insertion in Obese Patients: A Prospective, Single-Center Study [PDF]

Drug Design, Development and Therapy
Zhouya Xue,1,2,* Xiang Liu,1,2,* Weisheng Qian,1 Nan Yang,1 Yongyi Pan,1 Yong Zhou,1 Wei Jiang,1 Feng Li,1 Bin Qian1 1Department of Anesthesiology, The First People’s Hospital of Yancheng, The Yancheng Clinical College of Xuzhou Medical ...
Xue Z, Liu X, Qian W, Yang N, Pan Y, Zhou Y, Jiang W, Li F, Qian B   +8 more
doaj   +2 more sources

The Median Effective Dose of Oxytocin Needed to Prevent Uterine Atony During Cesarean Delivery in Elderly Parturients [PDF]

Drug Design, Development and Therapy, 2020
Chang Na Wei,1,2,* Jia Li Deng,1,2,* Jin Hua Dong,3 Ze Peng Ping,3 Xin Zhong Chen1,2 1Department of Anesthesia, Women’s Hospital, Zhejiang University School of Medicine, Hangzhou 310006, People’s Republic of China; 2Department of Anesthesia ...
Wei CN, Deng JL, Dong JH, Ping ZP, Chen XZ   +4 more
doaj   +2 more sources

Determination of the Median Effective Dose (ED50) of Ciprofol for Successful Sedation in Pediatric Patients During General Anesthesia Induction [PDF]

Drug Design, Development and Therapy
Peihe Nie,1 Di Wu,2 Chengjun Du,1 Xiaoqian Wang,1 Huan Zhang,1 Hongyi Xiao1 1Department of Anesthesiology, Weifang People’s Hospital, Weifang, 261041, People’s Republic of China; 2Department of Outpatient, Weifang People’s Hospital, Weifang, 261041 ...
Nie P, Wu D, Du C, Wang X, Zhang H, Xiao H   +5 more
doaj   +2 more sources

Antivenoms: potency or median effective dose, which to use? [PDF]

Journal of Venomous Animals and Toxins including Tropical Diseases, 2010
V Morais, S Ifran, P Berasain, H Massaldi   +3 more
doaj   +3 more sources

Exploring the Median Effective Dose of Ciprofol for Anesthesia Induction in Elderly Patients: Impact of Frailty on ED50 [PDF]

Drug Design, Development and Therapy
Jingjing Yuan,1,2,* Zenghui Liang,1,* Muhoza Bertrand Geoffrey,1 Yanle Xie,1,2 Shuhan Chen,1,2 Jing Liu,1,2 Yuzhong Xia,1 Huixin Li,1 Yanling Zhao,1 Yuanyuan Mao,1,2 Na Xing,1,2 Jianjun Yang,1,2 Zhongyu Wang,1 Fei Xing1,2 1Department of ...
Yuan J, Liang Z, Geoffrey MB, Xie Y, Chen S, Liu J, Xia Y, Li H, Zhao Y, Mao Y, Xing N, Yang J, Wang Z, Xing F   +13 more
doaj   +2 more sources

Effect of age on the median effective dose and 95% effective dose of intravenous fentanyl for blunting the hemodynamic response to tracheal intubation: A double-blind, up-and-down sequential method trial [PDF]

Journal of Anaesthesiology Clinical Pharmacology
Background and Aims: Control of the hemodynamic response during intubation is essential. To assess the effect of age on the median effective dose (ED50) and 95% effective dose (ED95) of fentanyl for blunting the hemodynamic response to intubation ...
Jatuporn Eiamcharoenwit, Phuping Akavipat   +1 more
doaj   +2 more sources

Effect of methotrexate on neurobehavior and cholinesterase in chicks [PDF]

Iraqi Journal of Veterinary Sciences, 2023
This reading aimed to determine the therapeutic index of methotrexate (MTX) with a note on the consequence of methotrexate in chicks on neurobehavioral in addition to calculating the activity for cholinesterase in plasma and brain in chicks.
Maab A. Fadel, Khayrea A. Mustafa, Imad A. Thanoon   +2 more
doaj   +1 more source

Assessing a 6-h endpoint observation time in the lethality neutralization assay used to evaluate the preclinical efficacy of snake antivenoms

Toxicon: X, 2021
The lethality neutralization assay in mice is the gold standard for the evaluation of the preclinical efficacy and specification fulfillment of snake antivenoms. However, owing to the animal suffering involved, this assay is a candidate to be replaced by
Gina Durán, Gabriela Solano, Aarón Gómez, Daniel Cordero, Adriana Sánchez, Mauren Villalta, Melvin Sánchez, Cecilia Díaz, José María Gutiérrez, Guillermo León   +9 more
doaj   +1 more source

ED50 of Propofol Combined with Nalbuphine on the Sedative Effect in Painless Hysteroscopy

Pain and Therapy, 2021
Introduction Nalbuphine has gradually become a commonly used clinical analgesic drug for painless hysteroscopy. The aim of our study was to identify the median effective dose (ED50) of propofol combined with nalbuphine for painless hysteroscopy.
Chen Chen, Weixiang Tang, Wei Ye, Weiwei Zhong, Yuanhai Li   +4 more
doaj   +1 more source