Effect of age on the median effective dose and 95% effective dose of intravenous fentanyl for blunting the hemodynamic response to tracheal intubation: A double-blind, up-and-down sequential method trial [PDF]
Journal of Anaesthesiology Clinical PharmacologyBackground and Aims: Control of the hemodynamic response during intubation is essential. To assess the effect of age on the median effective dose (ED50) and 95% effective dose (ED95) of fentanyl for blunting the hemodynamic response to intubation ...
Jatuporn Eiamcharoenwit +1 more
doaj +2 more sources
Effect of methotrexate on neurobehavior and cholinesterase in chicks [PDF]
Iraqi Journal of Veterinary Sciences, 2023 This reading aimed to determine the therapeutic index of methotrexate (MTX) with a note on the consequence of methotrexate in chicks on neurobehavioral in addition to calculating the activity for cholinesterase in plasma and brain in chicks.
Maab A. Fadel +2 more
doaj +1 more source
Toxicon: X, 2021 The lethality neutralization assay in mice is the gold standard for the evaluation of the preclinical efficacy and specification fulfillment of snake antivenoms. However, owing to the animal suffering involved, this assay is a candidate to be replaced by
Gina Durán +9 more
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ED50 of Propofol Combined with Nalbuphine on the Sedative Effect in Painless Hysteroscopy
Pain and Therapy, 2021 Introduction Nalbuphine has gradually become a commonly used clinical analgesic drug for painless hysteroscopy. The aim of our study was to identify the median effective dose (ED50) of propofol combined with nalbuphine for painless hysteroscopy.
Chen Chen +4 more
doaj +1 more source
Determination of pesticide toxicity parameters using probit-analysis
Карантин і захист рослин, 2023 Goal of the research is to consider the main concepts used in the probit-analysis method, the features of its application to determine the toxicity of pesticides, in particular insecticides, acaricides and fungicides. Methods.
O. Shevchuk +3 more
doaj +1 more source
Effect of Baricity of Bupivacaine on Median Effective Doses for Motor Block [PDF]
Medical Science Monitor, 2017 BACKGROUND The median effective dose (ED50) of a drug gives the amount or dose of drug needed to produce effective therapeutic response or desired effect in at least 50% of the population taking it. Our study focused on determining the ED50 required for effective motor block using hyperbaric and plain bupivacaine, and evaluated the influence of ...
Chen, Ming-quan, Chen, Chun, Li, Lin
openaire +2 more sources
Determination of the median effective dose of chloroprocaine in labour: preliminary results [PDF]
, 2015 Anssens, Sarah +4 more
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Ofatumumab and high-dose methylprednisolone for the treatment of patients with relapsed or refractory chronic lymphocytic leukemia. [PDF]
, 2014 Ofatumumab is a humanized anti-CD20 monoclonal antibody that has been approved by the FDA for the treatment of patients with chronic lymphocytic leukemia. We conducted a phase II single-arm study at a single center.
Almahasnah, E +6 more
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γ-H2AX foci as in vivo effect biomarker in children emphasize the importance to minimize x-ray doses in paediatric CT imaging [PDF]
, 2014 Objectives: Investigation of DNA damage induced by CT x-rays in paediatric patients versus patient dose in a multicentre setting. Methods: From 51 paediatric patients (median age, 3.8 years) who underwent an abdomen or chest CT examination in one of the
A. De Backer +9 more
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Brainstem metastases treated with Gamma Knife stereotactic radiosurgery: the Indiana University Health experience [PDF]
, 2018 Brainstem metastases offer a unique challenge in cancer treatment, yet stereotactic radiosurgery (SRS) has proven to be an effective modality in treating these tumors.
Ansari, Shaheryar +9 more
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