Results 41 to 50 of about 697,972 (287)

Prospective evaluation of a protocol for transitioning porcine lente insulintreated diabetic cats to human recombinant protamine zinc insulin [PDF]

, 2018
Objectives The objective was to evaluate a nadir-led protocol for transitioning porcine lente insulin suspension (PLIS)-treated diabetic cats onto human recombinant protamine zinc insulin (PZIR). Methods Recently diagnosed (
Church, D B, Forcada, Y, Gostelow, R, Hazuchova, K, Niessen, S J M, Scudder, C   +5 more
core   +2 more sources

Curing Hepatitis C in Liver Transplant Recipients Is Associated with Changes in Immunosuppressant Use. [PDF]

, 2016
Background and aimsAll-oral interferon-free antivirals are highly effective in treating recurrent hepatitis C (HCV) infection in liver transplant (LT) recipients.
Bau, Sherona, Busuttil, Ronald W, Choi, Gina, Durazo, Francisco, El Kabany, Mohammed, Elashoff, David, Farid, Alexander, Grotts, Jonathan, Han, Steven, Jamal, Naadir, Jimenez, Melissa, Rheem, Justin, Saab, Sammy   +12 more
core   +2 more sources

Iron Status and Analysis of Efficacy and Safety of Ferric Carboxymaltose Treatment in Patients with Inflammatory Bowel Disease [PDF]

, 2012
Background and Aims:We analyzed iron deficiency and the therapeutic response following intravenous ferric carboxymaltose in a large single-center inflammatory bowel disease (IBD) cohort.
Anker SD, Anker SD, Beate Löhr, Breymann C, Burkhard Göke, Carrier J, Chandler G, Cornelia Tillack, De Silva AD, Domenech E, Erichsen K, Erichsen K, Evstatiev R, Fabian Schnitzler, Fleming MD, Fleming RE, Florian Beigel, Ganz T, Gasche C, Gasche C, Julia Seiderer, Katsanos K, Kociol RD, Kulnigg S, Lomer MC, Maria Weidinger, Nemeth E, Nemeth E, Pizzi LT, Qunibi WY, Qunibi WY, Rüdiger P. Laubender, Schroder O, Semrin G, Simone Breiteneicher, Srigiridhar K, Stein J, Stephan Brand, Szczech LA, Tagboto S, Thomas Ochsenkühn, Van Wyck DB, Wells CW, Werner T, Wilson A, Wilson A   +45 more
core   +1 more source

Effect of anticomplement agent K-76 COOH in hamster-to-rat and guinea pig- to-rat xenotransplantation [PDF]

, 1995
In normal rats, the xenobiotic K76 inhibited the C5 and probably the C2 and C3 steps of complement and effectively depressed classical complement pathway activity, alternative complement pathway activity, and the C3 complement component during and well ...
Adachi, Anthony J. Demetris, Cochrane, Gewurz, Hasan, Hideaki Miyazawa, Hong, Iida, Kissmeyer-Nielsen, Kitano, Kitano, Leventhal, Minoru Nomoto, Mitsuko Tanaka, Miyagawa, Miyagawa, Miyazaki, Miyazaki, Miyazawa, Murase, Nelson, Noriko Murase, Ono, Perper, Pruitt, Pruitt, Qing Ye, Rafael Manez, Satoru Todo, Soares, Starzl, Starzl, Starzl, Starzl, Tanaka, Thomas E. Starzl, Valdivia, Van den Bogaerde, Wasei Miyazaki, Xia, Yamamoto, Yoichi Toyama   +41 more
core   +2 more sources

Optimum moving averages for the estimation of median effective dose in bioassay [PDF]

Epidemiology and Infection, 1963
Optimum forms of moving averages are derived for the estimation of LD 50 in the situation where no assumptions are made about the form of the dose-response distribution. The theory is also applied to uses of moving averages based on the angular transformation of the percentage response.
openaire   +2 more sources

Evaluating Antivenom Efficacy against Echis carinatus Venoms—Screening for In Vitro Alternatives

Toxins, 2022
In India, polyvalent antivenom is the mainstay treatment for snakebite envenoming. Due to batch-to-batch variation in antivenom production, manufacturers have to estimate its efficacy at each stage of IgG purification using the median effective dose ...
Siddharth Bhatia, Avni Blotra, Karthikeyan Vasudevan   +2 more
doaj   +1 more source

Fosmanogepix (APX001) Is Effective in the Treatment of Immunocompromised Mice Infected with Invasive Pulmonary Scedosporiosis or Disseminated Fusariosis. [PDF]

, 2020
There are limited treatment options for immunosuppressed patients with lethal invasive fungal infections due to Fusarium and Scedosporium Manogepix (MGX; APX001A) is a novel antifungal that targets the conserved Gwt1 enzyme required for localization of ...
Alkhazraji, Sondus, Alqarihi, Abdullah, Gebremariam, Teclegiorgis, Gu, Yiyou, Ibrahim, Ashraf S, Mamouei, Zeinab, Shaw, Karen J, Singh, Shakti, Wiederhold, Nathan P   +8 more
core   +1 more source

A cost effectiveness and capacity analysis for the introduction of universal rotavirus vaccination in Kenya : comparison between Rotarix and RotaTeq vaccines [PDF]

, 2012
Background Diarrhoea is an important cause of death in the developing world, and rotavirus is the single most important cause of diarrhoea associated mortality. Two vaccines (Rotarix and RotaTeq) are available to prevent rotavirus disease.
A Kerdpanich, Albert Jan van Hoek, Amina Ismail, B Girma, BA Lopman, CL Fischer Walker, D. James Nokes, David Mutonga, DE Atherly, DH Esposito, DJ Nokes, DJ Nokes, G Armah, J Nyangao, Jane Chuma, JE Tate, K Zaman, KJ Rothman, M Ombok, M Patel, Maarten Postma, MM Cortese, Mwanajuma Ngama, NM Kiulia, RE Black, S Flessa, S Madhi, Samuel Cheburet, T Ruuska, Tatu Kamau   +29 more
core   +3 more sources

Why and When Are Evidence‐Based Interventions Adopted in Paediatric Supportive Care? A Qualitative Exploration of the Determinants of Photobiomodulation Implementation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Oral mucositis is a common and debilitating side effect of childhood cancer and stem cell transplant treatments. It affects the quality of life of children and young people (CYP) and places a strain on services. Photobiomodulation is recommended for oral mucositis prevention in international guidance but is poorly implemented in UK ...
Claudia Heggie, Kara A. Gray‐Burrows, Peter F. Day, Bob Phillips, Carl A. Thompson   +4 more
wiley   +1 more source

The new algorithm for calculation of median lethal dose (LD50) and effective dose fifty (ED50) of Micrarus fulvius venom and anti-venom in mice

International Journal of Veterinary Science and Medicine, 2016
One million people throughout the world are bitten yearly by poisonous snakes. Of this, one-tenth died and three-tenth suffer some forms of disabilities.
Saganuwan Alhaji Saganuwan
doaj   +1 more source