Determination of the median effective dose (ED50) of spinal chloroprocaine in labour analgesia [PDF]
The primary goal of this study was to determine the median effective dose (ED50) of spinal chloroprocaine for labour analgesia. Thirty-eight parturients requesting neuraxial analgesia were enrolled.
De Hert, Stefan +13 more
core +1 more source
Median of the organ equivalent dose for each protocol by BEIR VII category (male and female) and effective dose (gender neutral). [PDF]
Median of the organ equivalent dose for each protocol by BEIR VII category (male and female) and effective dose (gender neutral).
Richard Fox (153532) +8 more
core +1 more source
A 1 year retrospective audit of quality indicators of clinical pharmacological advice for personalized linezolid dosing: One stone for two birds? [PDF]
Aim This study explored the clinical and economic impact of clinical pharmacological advice (CPA) (based on therapeutic drug monitoring [TDM] results, and on patients' characteristics and co-medications) on personalized linezolid therapy in a tertiary ...
Dose L., Pea F., Cojutti P., Baraldo M.
core +1 more source
Optimum moving averages for the estimation of median effective dose in bioassay [PDF]
Optimum forms of moving averages are derived for the estimation of LD 50 in the situation where no assumptions are made about the form of the dose-response distribution. The theory is also applied to uses of moving averages based on the angular transformation of the percentage response.
openaire +2 more sources
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo +5 more
wiley +1 more source
Effective Radiation Dose in CT Colonography: Is There a Downward Trend? [PDF]
Rationale and Objectives: Radiation dose is an important drawback of computed tomography (CT) colonography, especially for its use as a screening tool for colorectal cancer. It is therefore important to know the present radiation dose.
Venema, Henk W. +3 more
core +1 more source
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa +7 more
wiley +1 more source
Evaluating Antivenom Efficacy against Echis carinatus Venoms—Screening for In Vitro Alternatives
In India, polyvalent antivenom is the mainstay treatment for snakebite envenoming. Due to batch-to-batch variation in antivenom production, manufacturers have to estimate its efficacy at each stage of IgG purification using the median effective dose ...
Siddharth Bhatia +2 more
doaj +1 more source
The Effect of High-Dose Fentanyl on Human Median Nerve Somatosensory-Evoked Responses [PDF]
Median nerve somatosensory evoked responses (MnSSERs) were recorded in nine neurologically normal adult cardiac patients before and during the administration of high-dose fentanyl. MnSSERs were recorded prior to induction and at t = 20 min and t = 45 min postinduction. Fentanyl was administered as a slow bolus (53.2 +/- 9.1 micrograms X kg-1), followed
A, Schubert +3 more
openaire +2 more sources
Low-dose rituximab is effective in pemphigus [PDF]
Background Rituximab, an anti-CD20 antibody, was shown in open series studies to be effective in treating pemphigus at a dose of 4 x 375 mg m(-2) as approved for B-cell malignancies.
Horvath, B. +10 more
core +1 more source

