Results 41 to 50 of about 2,851 (170)

Efficacy and safety comparison of esketamine-propofol with nalbuphine-propofol for upper gastrointestinal endoscopy in children: a multi-center randomized controlled trial

open access: yesFrontiers in Pediatrics, 2023
Background and AimsAnesthetics such as propofol, esketamine and nalbuphine are used during the upper gastrointestinal endoscopy to achieve and maintain the desired sedation level.
Xiaosu Zheng   +8 more
doaj   +1 more source

Arterial spin labeling performs comparably to 2‐[18F]fluoro‐2‐deoxy‐D‐glucose positron emission tomography for presurgical evaluation in pediatric lesional epilepsy

open access: yesEpilepsia, Volume 67, Issue 6, Page 2940-2953, June 2026.
Abstract Objective This study was undertaken to test whether arterial spin labeling (ASL) performs comparably to 2‐[18F]fluoro‐2‐deoxy‐D‐glucose positron emission tomography (FDG‐PET), the mainstay functional imaging technique, in pediatric lesional epilepsy, while avoiding radiotracer exposure and additional sedation.
Antonio Giulio Gennari   +7 more
wiley   +1 more source

The effect of nalbuphine on prevention of emergence delirium in children: a systematic review with meta-analysis

open access: yesBrazilian Journal of Anesthesiology
Background: Emergence delirium remains a major postoperative concern for children undergoing surgery. Nalbuphine is a synthetic mixed agonist-antagonist opioid, which is believed to reduce the incidence of emergence delirium in children.
Ka Ting Ng   +3 more
doaj   +1 more source

Pain management of nalbuphine and sufentanil in patients admitted intensive care unit of different ages

open access: yesBMC Emergency Medicine, 2022
Background Pain relief for patients in the intensive care unit (ICU) can improve treatment outcomes and reduce the burden on doctors and nurses. This study aims to report the clinical analgesic and sedative effects of nalbuphine and sufentanil on ICU ...
Kaiqiang Ji   +4 more
doaj   +1 more source

Opioids in breast cancer: Between analgesia and modulation of tumour progression

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 9, Page 1727-1746, May 2026.
Preclinical investigations consistently demonstrate that activation of μ‐opioid receptors and δ‐opioid receptors promote proliferation, migration, angiogenesis, epithelial‐mesenchymal transition, acquisition of cancer stem cell phenotypes, and chemoresistance.
Marianna Ciwun   +2 more
wiley   +1 more source

Patient Characteristics and Risk of Fall‐Related Injuries Among New Users of Opioids in Denmark: A Longitudinal Descriptive Study

open access: yesPharmacoepidemiology and Drug Safety, Volume 35, Issue 4, April 2026.
ABSTRACT Purpose To assess the 1‐year risk of fall‐related injuries among new users of opioids in Denmark. Methods Using Danish health registers, we identified all new adult users of opioids between 2010 and 2022 (first time use within 5 years). We performed logistic regression and applied marginal comparisons to estimate risk ratios (RRs) associating ...
Juliane Maria Rosendahl   +5 more
wiley   +1 more source

Efficacy and Safety of Conventional and Biologic Therapies in Prurigo Nodularis: A Systematic Review and Meta‐Analysis

open access: yesInternational Journal of Dermatology, Volume 65, Issue 4, Page 724-736, April 2026.
ABSTRACT Prurigo nodularis (PN) is a chronic, intensely pruritic skin disorder characterized by hyperkeratotic nodules and a debilitating itch–scratch cycle. Conventional therapies have limited efficacy and safety issues, while biologics have recently emerged as a promising alternative.
Andrea Lancz   +7 more
wiley   +1 more source

Effect of Preventive Analgesia with Nalbuphine and Dexmedetomidine in Endoscopic Sinus Surgery

open access: yesPain Research and Management, 2022
Background. The study was to assess the efficacy and safety of nalbuphine combined with dexmedetomidine for preventive analgesia in endoscopic sinus surgery. Methods.
Pan Yu, Jie Zhang, Yan Zou, Jun Wang
doaj   +1 more source

Submicroscopic changes in the structural components of thymus under the action of nalbuphine on the body

open access: yesPatologìâ, 2017
In medicine narcotic analgesics have long been used for therapeutic purposes, but their influence on the organs of the immune system is insufficiently studied.
T. V. Harapko , A. S. Holovatskyi
doaj   +1 more source

Summary of Evidence for Perioperative Management of Day Surgery Patients Undergoing Anorectal Surgery

open access: yesNursing Open, Volume 13, Issue 1, January 2026.
ABSTRACT Aim This scoping review aimed to map and synthesise the available evidence on the perioperative management of patients undergoing anorectal surgery in a day‐surgery setting. This study creates the first unified, evidence‐based framework for day‐surgery anorectal care.
Yahui Gao, Mindan Wang, Yingying Jiang
wiley   +1 more source

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