Influence of Nalorphine on the Sphincter of Oddi Studied by Roentgencinematography [PDF]
It has long been known that morphine increases the tone of unstriated intestinal muscle in general and hence that of the sphincter of Oddi as well. Most substances belonging to the morphine group, both natural and synthetic, are considered to exercise a ...
P. Lindgren, G. Saltzman
semanticscholar +4 more sources
The effect of nalorphine on the antidiuretic action of morphine in rats and men. [PDF]
In several mammalian species the diuretic response to water given by mouth is inhibited by morphine. De Bodo (1944) concluded, from experiments on dogs, that this inhibition cannot be attributed to the effect of morphine on water absorption from the gut;
H. Schnieden, E. K. Blackmore
semanticscholar +5 more sources
Interactions Between Opioids and Dextroamphetamine on Locomotor Activity: Influence of an Opioid's Relative Efficacy at the Mu Receptor [PDF]
Opioids and stimulants are often used in combination for both recreational and non-recreational purposes. High-efficacy mu opioid agonists generally increase the behavioral effects of stimulants, whereas opioid receptor antagonists generally attenuate ...
Mark A. Smith+16 more
doaj +2 more sources
Conditioned nalorphine-induced abstinence changes: persistence in post morphine-dependent monkeys. [PDF]
Every tenth lever-press of three morphine-dependent rhesus monkeys was reinforced with food. A red light, initially a neutral stimulus, was presented every third or fourth session for 5 min before and 5 min after an intravenous injection of nalorphine, a
S. Goldberg, C. Schuster
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QUANTITATIVE STUDIES OF THE ANTAGONISM BY NALORPHINE OF SOME OF THE ACTIONS OF MORPHINE-LIKE ANALGESIC DRUGS. [PDF]
A quantitative investigation has been made of the antagonism by nalorphine of the analgesia and lenticular opacity produced in mice by a number of compounds.
B. Cox, M. Weinstock
semanticscholar +2 more sources
Activation profiles of opioid ligands in HEK cells expressing δ opioid receptors [PDF]
Background The aim of the present study was to characterize the activation profiles of 15 opioid ligands in transfected human embryonic kidney cells expressing only δ opioid receptors.
Clark J+3 more
doaj +3 more sources
Conditioned suppression by a stimulus associated with nalorphine in morphine-dependent monkeys. [PDF]
Three rhesus monkeys, physically dependent on morphine, were trained to press a lever for food on a fixed ratio of 10 responses. A tone, initially a neutral stimulus, was aperiodically presented every third or fourth session, 5 min before and after the ...
Stephen R. Goldberg, Charles R. Schuster
semanticscholar +2 more sources
Advances in the Physicochemical Profiling of Opioid Compounds of Therapeutic Interest. [PDF]
Who is in charge? In solutions, naloxone exists in four differently charged forms. Its overall lipophilicity profile indicated by the broad black line is the sum of the contributions of its four forms. Although the non‐charged form of naloxone is less lipophilic than naltrexone, its relative concentration at physiological pH is higher.
Mazák K, Noszál B, Hosztafi S.
europepmc +2 more sources
Activity of opioid ligands in cells expressing cloned mu opioid receptors [PDF]
BACKGROUND: The aim of the present study was to describe the activity of a set of opioid drugs, including partial agonists, in a cell system expressing only mu opioid receptors.
David Clark, J+3 more
exaly +3 more sources
Pharmacological profiles of opioid ligands at kappa opioid receptors [PDF]
BACKGROUND: The aim of the present study was to describe the activity of a set of opioid drugs, including partial agonists, in a human embryonic kidney cell system stably expressing only the mouse κ-opioid receptors.
Pamela J Shaw
exaly +3 more sources