Results 121 to 130 of about 101,541 (346)

Medication experiences in the treatment of opioid use disorders: Insights from Reddit

Addiction, EarlyView.
Abstract Background and Aims Better understanding the challenges faced by patients on medications for opioid use disorder (MOUD), including methadone and buprenorphine, is critical to increasing their use/retention. Social media platforms such as Reddit offer a space for patients to share their experiences with medications.
Alexandra Almeida, Mike Conway, David J. Grelotti, Amarnath Gupta, David Frank, Annick Bórquez   +5 more
wiley   +1 more source

Effectiveness of Scotland's National Naloxone Programme for reducing opioid‐related deaths: a before (2006–10) versus after (2011–13) comparison

Addiction, 2016
Aims To assess the effectiveness for Scotland's National Naloxone Programme (NNP) by comparison between 2006–10 (before) and 2011–13 (after NNP started in January 2011) and to assess cost‐effectiveness. Design This was a pre–post evaluation of a national
S. Bird, A. McAuley, Samantha Perry, C. Hunter   +3 more
semanticscholar   +1 more source

Conflict and communication: managing the multiple affordances of take-home naloxone administration events in Australia

Addiction Research and Theory, 2020
Opioid overdose is a growing issue in Australia. Programs to provide opioid consumers with ‘take-home’ naloxone to reverse overdose exist internationally and in some Australian cities, but uptake remains inconsistent.
A. Farrugia, J. Neale, R. Dwyer, Renae Fomiatti, S. Fraser, J. Strang, P. Dietze   +6 more
semanticscholar   +1 more source

Naloxone dosing in the era of synthetic opioids: Applying the Goldilocks principle

Addiction, EarlyView.
Abstract The opioid overdose epidemic remains a critical public health crisis. In recent years, synthetic opioids like fentanyl and nitazenes, have driven a sharp rise in deaths. Naloxone, an opioid receptor antagonist, has been established as a key intervention for reversing opioid overdoses and saving lives.
Mariana Gonzalez Utrilla, Edward Chesney, Joanne Neale, Nicola Metrebian, Nicola Kalk, Arne Kristian Skulberg, Paul Dietze, Martin Smith, John Strang   +8 more
wiley   +1 more source

Nitrous Oxide: Mechanism of Its Antinociceptive Action [PDF]

, 1995
Nitrous oxide (N2O) is an anesthetic gas known to produce an analgesic effect at sub-anesthetic concentrations. This analgesic property of N2O can be clinically exploited in a broad range of conditions where pain relief is indicated.
Quock, Raymond M., Vaughn, Linda K.
core   +1 more source

Association Between a State Law Allowing Pharmacists to Dispense Naloxone Without a Prescription and Naloxone Dispensing Rates

JAMA Network Open, 2020
Key Points Question Is an Ohio law allowing pharmacists to dispense naloxone without a prescription in accordance with a physician-approved protocol associated with an increase in naloxone dispensing rates?
N. Gangal, A. Hincapie, R. Jandarov, Stacey M. Frede, J. Boone, N. MacKinnon, Kathleen M. Koechlin, Jolene Defiore-Hyrmer, Amy E Holthusen, P. Heaton   +9 more
semanticscholar   +1 more source

Development and evaluation of a machine learning model to predict acute care for opioid use disorder among Medicaid enrollees engaged in a community‐based treatment program

Addiction, EarlyView.
Abstract Aims To develop machine‐learning algorithms for predicting the risk of a hospitalization or emergency department (ED) visit for opioid use disorder (OUD) (i.e. OUD acute events) in Pennsylvania Medicaid enrollees in the Opioid Use Disorder Centers of Excellence (COE) program and to evaluate the fairness of model performance across racial ...
Lingshu Xue, Ruofei Yin, Evan S. Cole, Wei‐Hsuan Lo‐Ciganic, Walid F. Gellad, Julie Donohue, Lu Tang   +6 more
wiley   +1 more source

The policy landscape for naloxone distribution in four states highly impacted by fatal opioid overdoses

Drug and Alcohol Dependence Reports, 2023
Background: Expanding access to naloxone is one of the most impactful interventions in decreasing opioid-related mortality. However, state distribution rates of naloxone are insufficient to meet community need.
Robert M. Bohler, Patricia R. Freeman, Jennifer Villani, Tim Hunt, Beth S. Linas, Alexander Y. Walley, Traci C. Green, Michelle R. Lofwall, Carly Bridden, Lisa A. Frazier, Laura C. Fanucchi, Jeffery C. Talbert, Redonna Chandler   +12 more
doaj  

Modifications of Gait as Predictors of Natural Osteoarthritis Progression in STR/Ort Mice [PDF]

, 2014
OBJECTIVE: Osteoarthritis (OA) is a common chronic disease for which disease-modifying therapies are not currently available. Studies to seek new targets for slowing the progress of OA rely on mouse models, but these do not allow for longitudinal ...
Bevan, S, Chang, Y M, De Souza, R, Fed Mato Grosso, Gentry, C, King's, Knights, C B, Pitsillides, A A, Poulet, B, UCL, Wilson, A M   +10 more
core   +4 more sources

Case series: Symptom‐inhibited fentanyl induction (SIFI) onto treatment‐dose opioid agonist therapy in a community setting

The American Journal on Addictions, Volume 34, Issue 3, Page 355-360, May 2025.
Abstract Background and Objectives Existing opioid agonist therapy (OAT) guidelines are far from sufficient to address rising opioid tolerances and potency of the unregulated opioid market in North America. Inadequate starting doses of OAT are a universally recognized barrier for people who use fentanyl.
Pouya Azar, Jane J. Kim, Ruth Davison, Zoran Barazanci, Martha J. Ignaszewski, James S. H. Wong, Jessica Machado, Marianne Harris, Michael Krausz, Nickie Mathew, Andrew Herring, Julio S. G. Montaner   +11 more
wiley   +1 more source