Results 121 to 130 of about 96,262 (339)
Elevated rate of suicide risk in individuals with opioid use disorder
Abstract Background and Objectives Few studies have longitudinally investigated suicide risk (SR) in opioid use disorder (OUD). This investigation administered three screening tools to individuals with OUD to compare rates of and variables associated with SR over 12 months.
Max Spaderna+19 more
wiley +1 more source
Naloxone Accessibility Across Mississippi [PDF]
Background/Objectives Despite widespread standing orders allowing pharmacies to dispense naloxone under protocol or without a prescription, there is substantial variation in naloxone availability and cost geographically.
Gravlee, Emily
core +1 more source
Naloxone Prescriptions Among Commercially Insured Individuals at High Risk of Opioid Overdose
This cohort study analyzes a nationwide database of commercially insured US individuals to determine how often naloxone is prescribed to individuals at high risk of opioid overdose.
Sarah Follman+4 more
semanticscholar +1 more source
Aims To assess the effectiveness for Scotland's National Naloxone Programme (NNP) by comparison between 2006–10 (before) and 2011–13 (after NNP started in January 2011) and to assess cost‐effectiveness. Design This was a pre–post evaluation of a national
S. Bird+3 more
semanticscholar +1 more source
ABSTRACT Aim To compare less invasive surfactant administration (LISA) and intubation‐surfactant‐extubation (INSURE) in infants born before 28 weeks gestational age (GA) by the need for mechanical ventilation (MV). Methods LISA was introduced in 2017 in our unit without formal prior LISA‐specific training as an equal alternative to INSURE.
C. Heiring+9 more
wiley +1 more source
The Prescription Opioid Epidemic: an Evidence-Based Approach [PDF]
A group of experts, led by researchers at the Johns Hopkins Bloomberg School of Public Health, issued this report aimed at stemming the prescription opioid epidemic, a crisis that kills an average of 44 people a day in the U.S.
G. Caleb Alexander, Shannon Frattaroli
core
ERNEST COST action overview on the (patho)physiology of GPCRs and orphan GPCRs in the nervous system
G protein‐coupled receptors (GPCRs) are a large family of cell surface receptors that play a critical role in nervous system function by transmitting signals between cells and their environment. They are involved in many, if not all, nervous system processes, and their dysfunction has been linked to various neurological disorders representing important
Necla Birgül Iyison+15 more
wiley +1 more source
Abstract Objective Due to the high prevalence of prescription opioid misuse, the US Food and Drug Administration (FDA) mandated a Risk Evaluation and Mitigation Strategy (REMS) requiring manufacturers of extended‐release/long‐acting (ER/LA) opioid analgesics to fund continuing education based on a FDA Blueprint.
Daniel P. Alford+6 more
wiley +1 more source
Abstract Background and Purpose Opioid use disorder (OUD) is a pressing public health concern marked by frequent relapse during periods of abstinence, perpetuated by negative affective states. Classical antidepressants or the currently prescribed opioid pharmacotherapies have limited efficacy to reverse the negative affect or prevent relapse ...
Andria Michael+7 more
wiley +1 more source
Nitrous Oxide: Mechanism of Its Antinociceptive Action [PDF]
Nitrous oxide (N2O) is an anesthetic gas known to produce an analgesic effect at sub-anesthetic concentrations. This analgesic property of N2O can be clinically exploited in a broad range of conditions where pain relief is indicated.
Quock, Raymond M., Vaughn, Linda K.
core +1 more source