Results 141 to 150 of about 78,245 (294)

Comprehensive User Engagement Sites (CUES) in Philadelphia: A Constructive Proposal [PDF]

open access: yes, 2018
This paper is a study about Philadelphia’s comprehensive user engagement sites (CUESs) as the authors address and examine issues related to the upcoming implementation of a CUES while seeking solutions for its disputed questions and plans. Beginning with
Clark, Peter   +12 more
core  

Naloxone prescription fills and use by patients treated for opioid use disorder by telehealth

open access: yesDrug and Alcohol Dependence Reports
Background: It is unknown how many people in treatment for opioid use disorder (OUD) have naloxone, use naloxone, and what their perceptions and barriers to obtaining it are.
Scott G. Weiner   +3 more
doaj   +1 more source

Pain Management in Aneurysmatic Subarachnoid Haemorrhage: A Survey of Nordic Physicians

open access: yesActa Anaesthesiologica Scandinavica, Volume 70, Issue 3, March 2026.
ABSTRACT Background Headache caused by aneurysmatic subarachnoid hemorrhage (aSAH) is often severe and may persist long after the ictus. Pharmacological pain management can be challenging due to poor efficacy or adverse effects. Multimodal pharmacotherapy is often required. Lack of guidelines and good quality clinical studies on pain management has led
Hanna Sariola   +14 more
wiley   +1 more source

Engagement in a National Naloxone Programme among people who inject drugs [PDF]

open access: yes, 2016
Bird, Sheila M.   +5 more
core   +2 more sources

Leveraging the ADAM10 prodomain for selective inhibition to enhance recovery after myocardial infarction

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 5, Page 990-1008, March 2026.
Background and Purpose Inflammation plays a crucial role in the development and progression of numerous acute and chronic diseases such as myocardial infarction (MI) and heart failure. Targeting ADAM proteases, particularly ADAM10, holds promise for fine‐tuning inflammatory responses.
Erik Klapproth   +16 more
wiley   +1 more source

Human Dorsal Root Ganglia Neuronal Cell Line to Study Nociceptive Signaling: A New Pipeline for Pain Therapy

open access: yesThe FASEB Journal, Volume 40, Issue 3, 15 February 2026.
The nociceptive properties of differentiated human HD10.6 cells were characterized by multiple approaches (A). Peripheral sensitization was induced within HD10.6 cells in response to an inflammatory cocktail (B), modeling nociceptors in a chronic pain state.
Sara A. Dochnal   +11 more
wiley   +1 more source

Esketamine/Ketamine: Dual‐Action Mechanisms and Clinical Prospects beyond Anesthesia in Psychiatry, Immunology, and Oncology

open access: yesAdvanced Science, Volume 13, Issue 7, 3 February 2026.
Esketamine and ketamine are widely used for perioperative analgesia and anesthesia. Despite their established roles in analgesia, sedation, and anesthesia, as well as emerging antidepressant, anti‐tumor, and anti‐inflammatory effects, their clinical use is limited due to side effects and addiction potential.
Yinxin Wang   +7 more
wiley   +1 more source

Consideration of naloxone. [PDF]

open access: yes, 2012
The ACMD has been considering the issue of naloxone availability and provision, as an intervention to prevent drug-related deaths, since 2009 and has previously written to the Medicines and Healthcare products Regulatory Agency (MHRA) concerning ...

core  

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