Results 151 to 160 of about 101,541 (346)

Targeting RNA Polymerase I in Ewing Sarcoma Treatment

open access: yesCancer Science, EarlyView.
Pharmacologic inhibition of RNA polymerase I activity represents a new therapeutic approach for Ewing sarcoma. This is the first time key components of the ribosome biogenesis pathway have been linked to Ewing sarcoma biology.
Alexis Bruce   +7 more
wiley   +1 more source

Choosing an analytic approach: Key study design considerations in state policy evaluation [PDF]

open access: yesarXiv
This paper reviews and details methods for state policy evaluation to guide selection of a research approach based on evaluation setting and available data. We highlight key design considerations for an analysis, including treatment and control group selection, timing of policy adoption, expected effect heterogeneity, and data considerations.
arxiv  

Extrachromosomal Circular DNA in Cancer: Mechanisms and Clinical Applications

open access: yesCell Proliferation, EarlyView.
ABSTRACT Extrachromosomal circular DNA (eccDNA) has emerged as a critical area of cancer research due to its ubiquitous presence in tumour cells and significant role in tumorigenesis, progression and drug resistance. Recent studies demonstrate that eccDNA promotes cancer progression by influencing genomic instability, amplifying oncogenes, regulating ...
Jiajia Li   +7 more
wiley   +1 more source

Readiness and recovery : switching between methadone and buprenorphine/naloxone for the treatment of opioid use disorder : a 90 credit thesis submitted in partial fulfillment of the requirements for the degree of Master of Nursing at Massey University, Wellington, New Zealand [PDF]

open access: yes, 2016
Opioid substitution treatment is an effective form of treatment for opioid use disorders. Long acting opiates are used as part of treatment with methadone and buprenorphine/naloxone (BUP/NX) most frequently prescribed.
Bishop, Blair Thomas
core  

Defining terminology and outcome measures for evaluating overdose response technology: An international Delphi study

open access: yesDrug and Alcohol Review, EarlyView.
Abstract Introduction Various novel harm reduction services leverage technology to reduce the rising number of drug poisoning deaths, particularly among those who use drugs alone. There is significant variability in terminology and outcome measures in reporting these interventions, complicating efforts to build a comprehensive knowledge base.
William Rioux   +16 more
wiley   +1 more source

Considering the Potential Benefits of Over-the-Counter Naloxone

open access: yesIntegrated Pharmacy Research and Practice, 2021
Kirk E Evoy,1 Lucas G Hill,2 Corey S Davis3 1University Health, Department of Pharmacy, The University of Texas at Austin College of Pharmacy, San Antonio, TX, USA; 2Pharmacy Practice, The University of Texas at Austin College of Pharmacy, Austin, TX ...
Evoy KE, Hill LG, Davis CS
doaj  

Buprenorphine–naloxone [PDF]

open access: yesCanadian Medical Association Journal, 2018
Tina, Hu, Larry, Nijmeh, Adam, Pyle
openaire   +2 more sources

Trends in novel opioid use and detections in exposures and police drug seizures in New South Wales

open access: yesDrug and Alcohol Review, EarlyView.
Abstract Introduction Novel opioids, including non‐medical and non‐opium‐based opioids such as fentanyl analogues and nitazenes, pose a significant risk of harm due to their high potency. There is little published data on novel opioid detections and harms in Australia, yet they are implicated in multiple deaths.
Janette L. Smith   +7 more
wiley   +1 more source

Home - About - Disclaimer - Privacy