Results 81 to 90 of about 41,379 (243)

Naloxone antagonizes the local antihyperalgesic effect of fentanyl in burnt skin of healthy humans

, 2007
The aim of this study was to investigate local opioid effects in the inflamed skin of healthy human volunteers. To induce inflammation, the circular tip of a 10-mm-diameter probe was heated to 48°C and applied for 120 seconds to a site on each forearm of
Hammond, G.R., Drummond, P.D., Robertson, L.   +2 more
core  

Benzodiazepine receptors and the control of ingestive behaviour in the rat [PDF]

, 1996
When administered systemically, benzodiazepine receptor agonists have been shown to increase food intake in a number of species. Conversely, benzodiazepine receptor inverse agonists bring about reliable decreases in feeding.
Higgs, Suzanne, Higgs, S
core  

Barriers and facilitators to detoxification from opioid substitution treatment: A mixed‐methods systematic review

Addiction, EarlyView.
Abstract Background and aims Despite the well‐documented benefits of opioid substitution treatment (OST) in treating opioid dependence (OD), many people diagnosed with OD desire to live a drug‐free life. The transition to abstinence involves detoxification: a gradual dose reduction of OST to zero milligrams.
Amy Bagshaw, Suleyman Shah, India Olchefske, Louise M. Paterson, Mike J. Crawford, Anne Lingford‐Hughes   +5 more
wiley   +1 more source

Naloxone-induced depolarization and synaptic activation of myenteric neurons in morphine-dependent guinea pig ileum

, 1987
Naloxone-induced depolarization and synaptic activation of myenteric neurons in morphine-dependent guinea pig ...
SM Johnson (16093475), JT Williams (16099025), M Costa (7774499), John Furness (13070439)   +3 more
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Naloxone distribution and possession following a large-scale naloxone programme

, 2018
Aims: To examine uptake following a large‐scale naloxone programme by estimating distribution rates since programme initiation and the proportion among a sample of high‐risk individuals who had attended naloxone training, currently possessed or had used ...
Gjersing, Linn Renathe, Clausen, Thomas, Madah-Amiri, Desiree   +2 more
core   +1 more source

Comparative effectiveness of alternative times to opioid agonist treatment taper initiation on taper completion and all‐cause mortality among people with opioid use disorder: A retrospective population‐based target trial emulation study in British Columbia, Canada, 2010–2020

Addiction, EarlyView.
Abstract Background and aims Opioid use disorder (OUD) treatment guidelines worldwide recommend opioid agonist treatment (OAT) as a long‐term, potentially indefinite treatment for managing OUD. However, many individuals express a strong interest in eventually tapering fully off treatment.
Ruyu Yan, Jeong Eun Min, Megan Kurz, Shaun R. Seaman, Paxton Bach, Sander Greenland, Paul Gustafson, Mohammad Ehsanul Karim, Lawrence McCandless, Robert William Platt, Uwe Siebert, María Eugenia Socías, Hui Xie, Bohdan Nosyk   +13 more
wiley   +1 more source

Low-dose naloxone provides an abuse-deterrent effect to buprenorphine

, 2015
Lynn R Webster,1 Michael D Smith,1 Cemal Unal,2 Andrew Finn3 1PRA Health Sciences, Salt Lake City, UT, USA; 2Biometrical Solutions LLC, Raleigh, NC, USA; 3BioDelivery Sciences International, Inc., Raleigh, NC, USA Abstract: In developmental research ...
Unal C, Finn A, Smith MD, Webster LR
core  

Naloxone Community Engagement Project

, 2023
This abstract focuses on the distribution of naloxone from Milton Family Medicine, a family medicine practice in rural Vermont. By interviewing representatives involved in the distribution of naloxone throughout the state, I pinpointed ways to best ...
Domingue, Olivia E
core  

Buprenorphine–naloxone [PDF]

Canadian Medical Association Journal, 2018
Tina, Hu, Larry, Nijmeh, Adam, Pyle
openaire   +2 more sources

Factors associated with readmission to residential treatment among clients transitioned from detoxification services in Alberta, Canada

The American Journal on Addictions, EarlyView.
Abstract Background and Objectives Readmission to residential treatment increases healthcare costs, strains publicly funded systems, and may not adequately meet clients' needs. This study examined rates and predictors of readmission to residential treatment among clients transitioned from detoxification services.
Abreham Mekonnen
wiley   +1 more source