Results 91 to 100 of about 65,278 (248)

Higher naloxone dosing in a quantitative systems pharmacology model that predicts naloxone-fentanyl competition at the opioid mu receptor level.

open access: yesPLoS ONE, 2020
Rapid resuscitation of an opioid overdose with naloxone, an opioid antagonist, is critical. We developed an opioid receptor quantitative systems pharmacology (QSP) model for evaluation of naloxone dosing.
Ronald B Moss   +6 more
doaj   +1 more source

Effects of tapentadol on pain, motor symptoms and cognitive functions in Parkinson\u2019s disease [PDF]

open access: yes, 2018
Background: Pain is a common and undertreated non-motor symptom in patients with Parkinson\u2019s disease (PD). Opioids have been seldom used in PD because they could worsen cognitive and motor functions.
Freo, Ulderico   +2 more
core  

Parasomnias and sleep‐related movement disorders induced by drugs in the adult population: a review about iatrogenic medication effects

open access: yesJournal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Parasomnias and sleep‐related movement disorders (SRMD) are major causes of sleep disorders and may be drug induced. The objective of this study was to conduct a systematic review of the literature to examine the association between drug use and the occurrence of parasomnias and SRMD.
Sylvain Dumont   +5 more
wiley   +1 more source

Buprenorphine–naloxone [PDF]

open access: yesCanadian Medical Association Journal, 2018
Tina, Hu, Larry, Nijmeh, Adam, Pyle
openaire   +2 more sources

Comparative Pharmacokinetics of Intranasal or Intramuscular Atipamezole in Unsedated Dogs and Efficacy for Reversal of Xylazine Sedation

open access: yesJournal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT The objectives of this study were to evaluate ATIP pharmacokinetics (PK) in healthy Beagle dogs after IM and IN dosing (Phase I), and to compare the rate of reversal of IM versus IN routes for xylazine (XYL) sedation (Phase II). This study was comprised of two sequential, randomized, crossover experiments. The initial PK study dosed ATIP by IN
Vanessa E. Cowan   +7 more
wiley   +1 more source

“They Look At Us Like Parasites”: The Corporeal Stigmatization and Pathologization of Deportees in Tijuana, Mexico

open access: yesMedical Anthropology Quarterly, EarlyView.
Abstract This article examines the embodied and institutional forms of marginalization experienced by Mexican deportees in Tijuana. Drawing on ethnographic fieldwork conducted in clinics and social service organizations, it explores how deportees are corporeally stigmatized, denied legal recognition, and pathologized as addicts in need of coercive ...
Carlos Martinez
wiley   +1 more source

Beta-Adrenergic Receptor Blockade By Propranolol Enhances Retention In A Multitrial Passive-Avoidance Procedure [PDF]

open access: yes, 2000
The effect of beta -adrenergic receptor blockade on retention in a mildly aversive passive-avoidance procedure was investigated. Rats were given passive-avoidance training-1 trial per day for 4 days-and were administered saline, the centrally and ...
Koven, Nancy, , \u2798   +4 more
core   +1 more source

Beyond safety net value(s): Tourist hotel rooms for people experiencing homelessness

open access: yesMedical Anthropology Quarterly, EarlyView.
Abstract This article examines the shape of care and value through an ethnographic study of an intensive, temporary housing intervention for people experiencing homelessness in San Francisco, California, during the COVID‐19 pandemic. Building on a new anthropological theory of value, the results highlight the slipperiness between surveillance and care,
Naomi C. Schoenfeld
wiley   +1 more source

Evaluation of the analgesic effect of 4-anilidopiperidine scaffold containing ureas and carbamates [PDF]

open access: yes, 2016
Fentanyl is a powerful opiate analgesic typically used for the treatment of severe and chronic pain, but its prescription is strongly limited by the well-documented side-effects.
Benyhe, Sa ́ndor   +18 more
core   +1 more source

That sinkin’ feeling: Environmentally induced distress on a disappearing island

open access: yesMedical Anthropology Quarterly, EarlyView.
Abstract Residents of Tangier Island, Virginia, a subsiding island in the Chesapeake Bay, embody psychosocial dimensions of environmental change. Analysis of ethnographic data shows islanders’ experiences and articulations of anxiety, panic, and despair as “that sinkin’ feeling,” resulting from the stress of living with the long‐term threat of imminent
Jonna Yarrington
wiley   +1 more source

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