Results 151 to 160 of about 4,819 (199)
Mitragynine and morphine produce dose-dependent bimodal action on food but not water intake in rats.
Am J Physiol Regul Integr Comp PhysiolZuarth Gonzalez JD +5 more
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International Journal of Pharmaceutics, 1999
The percolation theory is a statistical theory able to study chaotic or disordered systems that has been applied in the pharmaceutical field since 1987. Through the application of this theory, the design of controlled release inert matrices has been improved.
I, Caraballo +4 more
openaire +4 more sources
The percolation theory is a statistical theory able to study chaotic or disordered systems that has been applied in the pharmaceutical field since 1987. Through the application of this theory, the design of controlled release inert matrices has been improved.
I, Caraballo +4 more
openaire +4 more sources
Journal of Pharmaceutical Sciences, 2011
This study aimed at preparing and evaluating Span 60-based niosomes for ocular delivery of naltrexone hydrochloride (NTX). Selected charged lipids [dicetyl phosphate (DCP) and stearyl amine (STA)] and surfactants [poly-24-oxyethylene cholesteryl ether (C24) and sodium cholate (CH)] were investigated as bilayer membrane additives and prepared using four
Hamdy, Abdelkader +3 more
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This study aimed at preparing and evaluating Span 60-based niosomes for ocular delivery of naltrexone hydrochloride (NTX). Selected charged lipids [dicetyl phosphate (DCP) and stearyl amine (STA)] and surfactants [poly-24-oxyethylene cholesteryl ether (C24) and sodium cholate (CH)] were investigated as bilayer membrane additives and prepared using four
Hamdy, Abdelkader +3 more
openaire +4 more sources
Clonidine Hydrochloride Detoxification from Methadone Treatment-
Advances in Alcohol & Substance Abuse, 1984Treatment outcomes were compared for 2 groups of subjects detoxified from methadone using clonidine. One group of 12 subjects was encouraged to continue in treatment with naltrexone, while the other 12 subjects did not have naltrexone treatment available.
R A, Rawson +3 more
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Pharmaceutical Research, 2010
Transdermal delivery of drugs is often limited by formidable barrier properties of stratum corneum (SC). Microneedles (MN) enable creation of transient microchannels in the SC and bypass this barrier. Many reports have focused on the great effectiveness of MN in improving percutaneous flux values of a variety of drugs over a large molecular size ...
Mikolaj, Milewski, Audra L, Stinchcomb
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Transdermal delivery of drugs is often limited by formidable barrier properties of stratum corneum (SC). Microneedles (MN) enable creation of transient microchannels in the SC and bypass this barrier. Many reports have focused on the great effectiveness of MN in improving percutaneous flux values of a variety of drugs over a large molecular size ...
Mikolaj, Milewski, Audra L, Stinchcomb
openaire +2 more sources
Genetic Screening of Compounds Used in Drug Abuse Treatment I. Naltrexone Hydrochloride
Drug and Chemical Toxicology, 1978Several compounds used clinically in drug abuse therapy were evaluated for genetic activity in a series of in vitro assays. This initial report describes the results for one of these compounds, Naltrexone. Nalrexone is a relatively nontoxic drug antagonist related to Naloxone which appears to be effective in diminishing the euphoria and dependence upon
D, Brusick +4 more
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Human Psychopharmacology: Clinical and Experimental, 2009
AbstractRationaleMethadone and buprenorphine are among the most widely employed pharmacological treatments currently available for opioid addiction. Cognitive effects of buprenorphine in abstinent heroin abusers are nevertheless far from being understood.MethodsNeuropsychological performance of 18 buprenorphine‐maintained patients (BMP) was evaluated ...
Lambros, Messinis +6 more
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AbstractRationaleMethadone and buprenorphine are among the most widely employed pharmacological treatments currently available for opioid addiction. Cognitive effects of buprenorphine in abstinent heroin abusers are nevertheless far from being understood.MethodsNeuropsychological performance of 18 buprenorphine‐maintained patients (BMP) was evaluated ...
Lambros, Messinis +6 more
openaire +2 more sources
Advances in Therapy, 2010
Morphine sulfate and naltrexone hydrochloride extended release capsules, indicated for chronic moderate-to-severe pain, contain extended-release morphine pellets with a sequestered naltrexone core. If pellets are tampered by crushing, naltrexone is released to reduce morphine-induced effects that appeal to opioid abusers.
Franklin, Johnson +4 more
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Morphine sulfate and naltrexone hydrochloride extended release capsules, indicated for chronic moderate-to-severe pain, contain extended-release morphine pellets with a sequestered naltrexone core. If pellets are tampered by crushing, naltrexone is released to reduce morphine-induced effects that appeal to opioid abusers.
Franklin, Johnson +4 more
openaire +2 more sources