Results 151 to 160 of about 59,458 (179)
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Multivesicular liposomes for sustained release of naltrexone hydrochloride: design, characterization and in vitro/in vivo evaluation

Pharmaceutical Development and Technology, 2012
Multivesicular liposomes containing naltrexone hydrochloride (DepoNTX) was prepared by using the traditional DepoFoam technology and the key formulation factors on encapsulation efficiency and particle size were investigated. A morphological characterization and in vitro/in vivo release assay was also carried out.
Lijun, Sun   +4 more
openaire   +2 more sources

A Placebo-Controlled, Double-Blind Crossover Study of Naltrexone Hydrochloride in Outpatients with Normal Weight Bulimia

Journal of Clinical Psychopharmacology, 1989
The endogenous opioid system plays an important role in the control of feeding behavior. Previous research has shown that antagonism of endogenous opioids will suppress feeding in certain models in both human and infrahuman species. In the current study, 16 normal-weight bulimic women were treated with low-dose naltrexone, the long-acting, orally ...
J E, Mitchell   +6 more
openaire   +2 more sources

Chemical stability of naltrexone hydrochloride injection.

International journal of pharmaceutical compounding, 2015
The chemical stability of naltrexone hydrochloride injection was studied by using a stability-indicating high-performance liquid chromatographic assay method that was developed in our laboratory. The concentrations of the drug were related directly to peak heights, and the percent relative standard deviation based on five injections was 1.0.
openaire   +1 more source

Physicochemical Stability of Compounded Naltrexone Hydrochloride Solutions in PCCA Base SuspendIt.

International journal of pharmaceutical compounding, 2019
Naltrexone hydrochloride is an orally active narcotic antagonist used to facilitate rapid transition from methadone maintenance. The dosing schedule of naltrexone hydrochloride in detoxification protocols needs to be flexible to permit precise, customized dose titration for individual patients.
Yashoda V, Pramar   +5 more
openaire   +1 more source

Naltrexone hydrochloride (Trexan): a review of serum transaminase elevations at high dosage.

NIDA research monograph, 1986
In summary, evidence is presented associating typically asymptomatic and reversible elevations of serum transaminase values with high daily dosages of naltrexone. Statistical significance was found only between placebo and the 300 mg dosage. Subjects aged 40 years and over were significantly more likely to develop this finding than younger subjects ...
D N, Pfohl   +6 more
openaire   +1 more source

Simultaneous Estimation of Naltrexone Hydrochloride and Zonisamide in Synthetic Mixture by RP-HPLC Method

Research Journal of Pharmacy and Technology
A simple, rapid, precise, and reproducible RP-HPLC method development and validation done for simultaneous estimation of Naltrexone Hydrochloride and Zonisamide in synthetic mixture. The isocratic method was developed usinɡ a Water Symmetry C18 (250 mm X 4.6 mm, 5 µm) column.
Sejal Dhaduk   +5 more
openaire   +1 more source

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