Results 51 to 60 of about 59,458 (179)

Multi‐scale maternal behavioral responses by white‐tailed deer to coyote predation risk

The Journal of Wildlife Management, Volume 90, Issue 1, January 2026.
In the piedmont region of the southeastern US, white‐tailed deer adjust maternal care strategies in response to variation in risk of encountering coyotes. In areas frequented by coyotes, adult female deer (i.e., does) increase their use of space, likely to avoid drawing coyotes to the location where a fawn is hidden.
Michael S. Muthersbaugh, Wesley W. Boone, Elizabeth A. Saldo, Alex J. Jensen, Charles Ruth, Jay Cantrell, John C. Kilgo, David S. Jachowski   +7 more
wiley   +1 more source

A Population Pharmacokinetic Model to Assess the Cytochrome P450 2B6 Metabolic Probe Bupropion and Hydroxybupropion in Vitamin D‐Insufficient and ‐Replete Patients With Kidney Disease

Journal of Clinical Pharmacy and Therapeutics, Volume 2026, Issue 1, 2026.
Objective The aim of this study was to use bupropion as a cytochrome P450 (CYP) 2B6 probe to determine CYP2B6 function by using a population pharmacokinetic approach of parent bupropion and metabolite hydroxybupropion to explore the impacts of chronic kidney disease (CKD) and vitamin D status in patients and control subjects.
Avisek Ghimire, Stacey M. Tuey, Linda Prebehalla, Amandla Atilano-Roque, Gavriel Roda, Lauren E. Thompson, Michel B. Chonchol, Nirav Shah, Michael F. Wempe, Thomas D. Nolin, Melanie S. Joy, Irina B. Bondareva   +11 more
wiley   +1 more source

Voltammetric determination of chlorpromazine hydrochloride and promethazine hydrochloride with the use of multivariate calibration

, 2001
The voltammetric behavior of antipsychotic drugs, such as, chlorpromazine hydrochloride and promethazine hydrochloride has been investigated at a glassy carbon electrode in Britton–Robinson buffer of pH 9.
Wang, li, Kokot, Serge, Li Wang, Yongnian Ni, Ni, Yongnian, Serge Kokot   +5 more
core   +1 more source

Combination of naltrexone and isotretinoin for the treatment of darier disease

, 2023
Darier disease (DD) is an autosomal-dominant genodermatosis in which mutations in the ATP2A2 gene result in impaired intercellular adhesion and epidermal blistering.
Costa, Tomás, Duarte, Bruno, Pinto, Gabriela Marques, Rebelo, Clarisse   +3 more
core   +1 more source

Biological Evaluation of Swintonia floribunda Leaf Extract Through Integrated GC‐MS, In Vivo, In Vitro, and In Silico Approaches Targeting Diarrhea, Pain, Fever, and Inflammation

Journal of Food Biochemistry, Volume 2026, Issue 1, 2026.
Background Swintonia floribunda, a member of the Anacardiaceae family, is a traditional medicinal plant in Bangladesh. The present study aimed to identify potential therapeutic agents from Swintonia floribunda leaves. Accordingly, we evaluated the methanolic extract of Swintonia floribunda leaves (MESFL) for anti‐inflammatory, antinociceptive ...
Farjana Akter Nipa, Mst. Riniara Khatun, Israt Jahan, Md Shirajul Islam, Sabbir Khan, Shariful Islam, Jannatul Nisa Nipa, Mahathir Mohammad, Md. Anisul Islam, Trishala Dutta, Md. Mustafiz Chowdhury, Mycal Dutta, Anupama Bose   +12 more
wiley   +1 more source

The Concise Guide to PHARMACOLOGY 2025/26: G protein‐coupled receptors

British Journal of Pharmacology, Volume 182, Issue S1, Page S24-S151, December 2025.
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander, Anthony P. Davenport, Eamonn Kelly, Alasdair J. Gibb, Alistair A. Mathie, Chloe J. Peach, Emma L. Veale, Jane F. Armstrong, Elena Faccenda, Simon D. Harding, Christopher Southan, Jamie A. Davies, Maria Pia Abbracchio, George R. Abraham, Alexander Agoulnik, Wayne Alexander, Khaled Al‐hosaini, Magnus Bäck, Jillian G. Baker, Nicholas M. Barnes, Ross Bathgate, Jean‐Martin Beaulieu, Annette G. Beck‐Sickinger, Maik Behrens, Kirstie A. Bennett, Kenneth E. Bernstein, Bernhard Bettler, Nigel J. M. Birdsall, Victoria A. Blaho, Pascal Bonaventure, Francois Boulay, Corinne Bousquet, Hans Bräuner‐Osborne, Andrew J. Brown, Geoffrey Burnstock, Marta Busnelli, Girolamo Caló, Vanni Caruso, Justo P. Castaño, Kevin J. Catt, Stefania Ceruti, Paul Chazot, Nan Chiang, Bice Chini, Arthur Christopoulos, Jerold Chun, Antonia Cianciulli, Olivier Civelli, Lucie H. Clapp, Réjean Couture, Helen M. Cox, Zsolt Csaba, Claes Dahlgren, Frank M. Dautzenberg, Gordon Dent, Steven D. Douglas, Pascal Dournaud, Margarita L. Dubocovich, Satoru Eguchi, Emanuel Escher, Edward J. Filardo, Tung Fong, Huamei Fu Forsman, Marta Fumagalli, Raul R. Gainetdinov, Michael L. Garelja, Marc de Gasparo, Florence Gbahou, Craig Gerard, Marvin Gershengorn, Michelle Glass, David E. Gloriam, Fernand Gobeil, Theodore L. Goodfriend, Cyril Goudet, Lukas Grätz, Karen J. Gregory, Christian Gruber, Andrew L. Gundlach, Jörg Hamann, Julien Hanson, Deborah S. Hartman, Richard L. Hauger, Debbie L. Hay, Akos Heinemann, Laura Heitman, Deron R. Herr, Morley D. Hollenberg, Nicholas D. Holliday, Birgitte Holst, Mastgugu Horiuchi, Daniel Hoyer, László Hunyady, Ahsan Husain, Adriaan P. IJzerman, Tadashi Inagami, Paul A. Insel, Kenneth A. Jacobson, Laura H. Jacobson, Robert T. Jensen, Ralf Jockers, Deepa Jonnalagadda, Sadashiva Karnik, Klemens Kaupmann, Jacqueline Kemp, Charles Kennedy, Yasuyuki Kihara, Julia Kinsolving, Takio Kitazawa, Pawel Kozielewicz, Hans‐Jürgen Kreienkamp, Jyrki P. Kukkonen, Luxmichan Laishram, Tobias Langenhan, Christopher J. Langmead, Dan Larhammar, Katie Leach, Davide Lecca, John D. Lee, Susan E. Leeman, Jérôme Leprince, Rob Leurs, Xaria X. Li, Ines Liebscher, Stephen J. Lolait, Amelie Lupp, Robyn Macrae, Janet J. Maguire, Davide Malfacini, Maurice Manning, Davide Marangon, Kirill Martemyanov, Jean Mazella, Craig A. McArdle, Shlomo Melmed, Martin C. Michel, Laurence J. Miller, Vincenzo Mitolo, Bernard Mouillac, Christa E. Müller, Philip M. Murphy, Jean‐Louis Nahon, Richard R. Neubig, Tony Ngo, Xavier Norel, Duuamene Nyimanu, Anne‐Marie O’Carroll, Stefan Offermanns, Maria Antonietta Panaro, Marc Parmentier, Nicole Perry‐Hauser, Roger G. Pertwee, Jean‐Philippe Pin, Eric R. Prossnitz, Helena Chengxue Qin, Mark Quinn, Stefano Raffaele, Rithwik Ramachandran, Manisha Ray, Rainer K. Reinscheid, Alejandro Romeral Buzón, Philippe Rondard, Mette M. Rosenkilde, G. Enrico Rovati, Chiara Ruzza, Gareth J. Sanger, Nicole Scholz, Torsten Schöneberg, Gunnar Schulte, Stefan Schulz, Deborah L. Segaloff, Charles N. Serhan, Arun K. Shukla, Khuraijam Dhanachandra Singh, Craig M. Smith, Nicola J. Smith, Claudia Stäubert, Leigh A. Stoddart, Yukihiko Sugimoto, Roger Summers, Valerie P. Tan, David M. Thal, Walter ( Wally) Thomas, Pieter B. M. W. M. Timmermans, Kalyan Tirupula, Lawrence Toll, Giovanni Tulipano, Hamiyet Unal, Thomas Unger, Celine Valant, Patrick Vanderheyden, David Vaudry, Hubert Vaudry, Joseph G. Verbalis, Jean‐Pierre Vilardaga, Christopher S. Walker, Ji Ming Wang, Donald T. Ward, Hans‐Jürgen Wester, Gary B. Willars, Tom Lloyd Williams, Trent M. Woodruff, Huixian Wu, Cheng Yang, Chengcan Yao, Richard D. Ye, Nathan Zaidman   +206 more
wiley   +1 more source

Management of xylazine toxicity, overdose, dependence, and withdrawal: A systematic review

The American Journal on Addictions, Volume 34, Issue 6, Page 589-602, November 2025.
Abstract Background and Objectives Xylazine, an alpha‐2‐adrenergic agonist, has been increasingly implicated in substance use and overdose crises. However, little is known about its effects on humans. With the growing public health crisis surrounding xylazine, it has become important to recognize and promptly manage symptoms of xylazine toxicity ...
Philipa Owusu‐Antwi, Priya Atodaria, Edmund Appiah‐Kubi, Zainab Shah, Elpidio Marlon Garcia   +4 more
wiley   +1 more source

Estimation of efficiency of double emulsification method for the preparation of naltrexone microspheres based on poly(lactic-co-glycolic acid) copolymer

Тонкие химические технологии, 2013
Administration of drug delivery systems allows reaching therapeutic efficiency in comparison with traditional dosage forms. Microspheres are used quite often as drug delivery systems in pharmaceutical technology.
E. A. Petrova, S. A. Kedik, K. V. Alekseev, E. V. Blynskaya, A. V. Panov, V. V. Suslov, N. V. Tikhonova   +6 more
doaj  

Effectiveness of injectable extended-release naltrexone vs daily buprenorphine–naloxone for opioid dependence: a randomized clinical noninferiority trial. [PDF]

, 2018
Key points from summary and commentary A novel study testing the relative effectiveness of injections of extended-release naltrexone and a daily combination of oral buprenorphine hydrochloride and naloxone hydrochloride for maintaining abstinence from ...

core  

Pharmacological treatment of obesity: an overview of different groups of anti-obesity drugs available in Poland

Journal of Education, Health and Sport
Introduction and Objective: Obesity, as one of the diseases of civilization, has become a significant problem in our time. Although the first ways of treating it appeared many years ago, pharmacotherapy of obesity has been developing significantly in ...
Barbara Woch, Dawid Bereza, Katarzyna Sokołowska, Maria Kulak, Igor Moreau, Paulina Polańska, Miriam Lang   +6 more
doaj   +1 more source