Results 61 to 70 of about 59,458 (179)

Molecular docking, molecular dynamics simulation, preparation, and characterization of naltrexone-phospholipid complex: A novel cargo with improved loading into multivesicular liposomes

Results in Chemistry
Naltrexone hydrochloride (NTX), a water-soluble opioid receptor antagonist, is prescribed widely for opioid and alcohol dependence and pain reduction. However, the significant limitations of NTX are low lipophilicity and extensive first-pass metabolism ...
Reihaneh Yousefi, Yasaman Rezaee, Fereshteh Bayat, Elham Rezaee, Leila Karami, Simin Dadashzadeh, Azadeh Haeri   +6 more
doaj   +1 more source

Over the counter naloxone nasal spray: A new hope for opioid crisis management in Pakistan

Journal of the Pakistan Medical Association
Opioids, derived from the poppy plant, include synthetic and partially synthetic compounds that bind to brain receptors, diminishing pain perception. Primarily prescribed as analgesics, they are often misused for euphoria, thus making opioid overdose a ...
Zmarak Ahmed Khan, Zainab Anfaal, Muhammad Shaheer   +2 more
doaj   +1 more source

Dissolution Assay of Bupropion/Naltrexone Hydrochloride Salts of Bilayer Composition Tablets Following the Development and Validation of a Novel HPLC Method. [PDF]

Materials (Basel), 2022
Apostolidi A, Protopapa C, Siamidi A, Vlachou M, Dotsikas Y.   +4 more
europepmc   +1 more source

Blood naltrexone levels over time following naltrexone implant [PDF]

, 2008
Aims: Oral naltrexone is used in the management of both heroin and alcohol dependence. However, poor compliance has limited its clinical utility. The study's objective was to determine the period of therapeutic coverage (= 2 ng/ml) provided by a 3.3 g ...
H. Ngo (23315191), R. Hansson (23310535), G. Hulse (23315188), Robert Tait (23315194), D. Arnold-Reed (23316610)   +4 more
core   +2 more sources

An eco-friendly smartphone based HPTLC method versus conventional densitometric one for determination of Naltrexone and Bupropion

BMC Chemistry
The rapid uprising technologies of smartphone applications and software introduced a new era for analytical detection techniques. It has transformed bench-top laboratory methods into simpler ones depending on cost-effective, portable, and widely ...
Eman M. Moaaz, Ezzat M. Abdel-Moety, Mamdouh R. Rezk, Ahmed S. Fayed   +3 more
doaj   +1 more source

Treatment of opiate dependency : a multimodal model using naltrexone

, 2010
The portfolio examines use of opiate antagonist medication (naltrexone hydrochloride) as a safe and effective treatment for opiate dependence.
Ross. Colquhoun (13785940)
core  

Naltrexone in the treatment of male alcoholics - an effectiveness study in Singapore

, 2001
Naltrexone has been demonstrated in western studies to be a useful pharmacological adjunct within treatment programmes for alcoholic patients. We report the first study of its efficacy and usefulness in an Asian region. This project was designed to allow
Tan, S., Lim, D., Wong, K. E., Parker, G., Hall, W. D., Lee, A., Winslow, R. M., Allen, J.   +7 more
core   +1 more source

Berberine hydrochloride: anticancer activity and nanoparticulate delivery system

, 2011
Wen Tan, Yingbo Li, Meiwan Chen, Yitao WangState Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao Special Administrative Region, ChinaBackground: Berberine hydrochloride is a ...
null Li, Li YB, Wen Tan, Tan W, Yitao Wang, Chen MW, Wang YT, Meiwan Chen   +7 more
core   +1 more source

Perioperative naltrexone management: a scoping review by the perioperative pain and addiction interdisciplinary network.

Substance use disorders, including alcohol use disorder, are a public health concern that affect more than 150 million people globally. The opioid antagonist naltrexone is being increasingly prescribed to treat opioid use disorder, alcohol use disorder ...
Wu, Mia, Kohan, Lynn, Iyayi, Mudia, Kapoor, Bhavya, Clarke, Hance A, Goel, Akash, Englesakis, Marina, Ladha, Karim S   +7 more
core   +1 more source

Thermosensitive Pluronic® hydrogel: prolonged injectable formulation for drug abuse

Drug Design, Development and Therapy, 2010
Katayoun Derakhshandeh1, Mahtab Fashi1, Seyedalireza Seifoleslami21Department of Pharmaceutics, Faculty of Pharmacy, University of Medical Science, Kermanshah; 2Research and Development Department, Forensic Medicine Organization, Kermanshah ...
Katayoun Derakhshandeh, Mahtab Fashi, Seyedalireza Seifoleslami   +2 more
doaj