New Construction of Functionalized CuO/Al2O3 Nanocomposite-Based Polymeric Sensor for Potentiometric Estimation of Naltrexone Hydrochloride in Commercial Formulations. [PDF]
Polymers (Basel), 2021 Al-Mohaimeed AM +2 more
europepmc +1 more source
Naltrexone-assisted rapid methadone discontinuation : a pilot study [PDF]
, 2009 Rapport de Synthèse : Un sevrage lent comme méthode élective pour l'interruption de la méthadone est coûteux en termes de temps, le plus souvent associé à un taux élevé d'abandon.
Camarasa Perez, J.
core
Tonic inhibition of accumbal spiny neurons by extrasynaptic 4 GABAA receptors modulates the actions of psychostimulants [PDF]
, 2014 Within the nucleus accumbens (NAc), synaptic GABAA receptors (GABAARs) mediate phasic inhibition of medium spiny neurons (MSNs) and influence behavioral responses to cocaine.
Belelli, D +8 more
core +1 more source
Thermosensitive Pluronic® hydrogel: prolonged injectable formulation for drug abuse
Drug Design, Development and Therapy, 2010 Katayoun Derakhshandeh1, Mahtab Fashi1, Seyedalireza Seifoleslami21Department of Pharmaceutics, Faculty of Pharmacy, University of Medical Science, Kermanshah; 2Research and Development Department, Forensic Medicine Organization, Kermanshah ...
Katayoun Derakhshandeh +2 more
doaj
An Exploratory Study of Suboxone (Buprenorphine/ Naloxone) Film Splitting: Cutting Methods, Content Uniformity, and Stability [PDF]
, 2019 Suboxone films are U.S. Food and Drug Administration approved to treat opioid dependence. While the package insert states that films should not be cut, physicians often prescribe film fractions for treatment and tapering. There is no data to support this
Conn, Kelly +6 more
core +1 more source
Combining the α1-Adrenergic Receptor Antagonist, Prazosin, with the β-Adrenergic Receptor Antagonist, Propranolol, Reduces Alcohol Drinking More Effectively Than Either Drug Alone [PDF]
, 2014 Background Evidence suggests that activation of the noradrenergic system may contribute to alcohol drinking in animals and humans. Our previous studies demonstrated that blocking α1-adrenergic receptors with the antagonist, prazosin, decreased alcohol ...
Beckwith, Lauren E +3 more
core +1 more source
Antinociceptive effects of morphine and naloxone in mu-opioid receptor knockout mice transfected with the MORS196A gene [PDF]
, 2010 Background Opioid analgesics such as morphine and meperidine have been used to control moderate to severe pain for many years. However, these opioids have many side effects, including the development of tolerance and dependence after long-term use, which
Shiou-Lan Chen +6 more
core +2 more sources
Frontiers in ImmunologyIntroductionRecently, we reported that post COVID-19 condition patients also have Transient Receptor Potential Melastatin 3 (TRPM3) ion channel dysfunction, a potential biomarker reported in natural killer (NK) cells from Myalgic Encephalomyelitis ...
Etianne Martini Sasso +13 more
doaj +1 more source
Therapeutic and toxic blood concentrations of nearly 1,000 drugs and other xenobiotics [PDF]
, 2012 Introduction: In order to assess the significance of drug levels measured in intensive care medicine, clinical and forensic toxicology, as well as for therapeutic drug monitoring, it is essential that a comprehensive collection of data is readily ...
Andresen, Hilke +3 more
core +1 more source
Synthesis, biological evaluation, and utility of fluorescent ligands targeting the μ-opioid receptor [PDF]
, 2015 Fluorescently labeled ligands are useful pharmacological research tools for studying receptor localization, trafficking, and signaling processes via fluorescence imaging. They are also employed in fluorescent binding assays. This study is centered on the
Briddon, Stephen J. +6 more
core +4 more sources