Results 1 to 10 of about 14,981 (159)

Through the Eyes of Patients: Understanding Treatment Burden of Intravitreal Anti-VEGF Injections for nAMD Patients in Norway

Clinical Ophthalmology, 2023
Gudrun Reitan,1 Inga Britt Kjellevold Haugen,2 Kristoffer Andersen,3 Ragnheidur Bragadottir,4,5 Christian Bindesbøll3 1Department of Molecular Medicine, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway; 2Department of Research, The ...
Reitan G, Kjellevold Haugen IB, Andersen K, Bragadottir R, Bindesbøll C   +4 more
doaj   +2 more sources

Scalable molecular dynamics on CPU and GPU architectures with NAMD

Journal of Chemical Physics, 2020
NAMDis a molecular dynamics program designed for high-performance simulations of very large biological objects on CPU- and GPU-based architectures. NAMD offers scalable performance on petascale parallel supercomputers consisting of hundreds of thousands ...
James C Phillips, David J Hardy, Julio Daniel Carvalho Maia   +2 more
exaly   +2 more sources

Impact of macular fluid volume fluctuations on visual acuity during anti-VEGF therapy in eyes with nAMD

Eye, 2021
To study the effect of repeated retinal thickness fluctuations during the anti-VEGF therapy maintenance phase in neovascular age-related macular degeneration (nAMD). Data were extracted from electronic medical records of 381 nAMD patients, aged ≥50 years;
Usha Chakravarthy
exaly   +2 more sources

New and Innovative Treatments for Neovascular Age-Related Macular Degeneration (nAMD)

Journal of Clinical Medicine, 2021
Age-related macular degeneration (AMD) is one of the most common causes of vision loss. Advanced forms of AMD are seen in primarily two types—neovascular AMD (nAMD) with the presence of choroid neovascularization and non-neovascular AMD (nnAMD) with ...
P. Patel, V. Sheth
exaly   +2 more sources

Impact on Visual Acuity in Neovascular Age Related Macular Degeneration (nAMD) in Europe Due to COVID-19 Pandemic Lockdown

Journal of Clinical Medicine, 2021
This is a retrospective, multicenter study of consecutive patients with nAMD scheduled for a visit and/or a treatment with an intravitreal injection (IVI) during the 3 months before lockdown in the Ophthalmology Departments of six centers of Europe.The ...
Carolina Arruabarrena, Mario Damiano Toro, Boris E Malyugin   +2 more
exaly   +2 more sources

py-MCMD: Python Software for Performing Hybrid Monte Carlo/Molecular Dynamics Simulations with GOMC and NAMD

Journal of Chemical Theory and Computation, 2022
py-MCMD, an open-source Python software, provides a robust workflow layer that manages communication of relevant system information between the simulation engines NAMD and GOMC and generates coherent thermodynamic properties and trajectories for analysis.
Mohammad Soroush Barhaghi, Brad Crawford, Gregory Schwing   +2 more
exaly   +2 more sources

Histopathologic evidence of VEGF in early neovascular AMD: from a 1992 hypothesis to a 1994 discovery — a historical perspective [PDF]

International Journal of Retina and Vitreous
Background In the early1990s, neovascular age-related macular degeneration (nAMD) was the leading cause of irreversible vision loss in older adults, yet its molecular basis remained unknown.
K. Alexander Dastgheib
doaj   +2 more sources

Computing Relative Binding Affinity of Ligands to Receptor: An Effective Hybrid Single-Dual-Topology Free-Energy Perturbation Approach in NAMD

Journal of Chemical Information and Modeling, 2019
An effective hybrid single-dual topology protocol is designed for the calculation of relative binding affinities of small ligands to a receptor. The protocol was developed as an expansion of the NAMD molecular dynamics program, which exclusively supports
Wei Jiang, Christophe Chipot, Benoı̂t Roux   +2 more
exaly   +2 more sources

Scalable molecular dynamics with NAMD

Journal of Computational Chemistry, 2005
James C Phillips, Rosemary I Braun, Emad Tajkhorshid   +2 more
exaly   +2 more sources

Incidence, clinical features, risk factors, and outcomes of Intraocular inflammation following Brolucizumab in Indian eyes – A multicentric study

Indian Journal of Ophthalmology, 2023
Purpose: To report the incidence, clinical features, potential risk factors, and outcomes of intraocular inflammation (IOI) following brolucizumab in Indian eyes. Methods: All consecutive patients diagnosed with brolucizumab-induced IOI from 10 centers
Debdulal Chakraborty, Soumen Mondal, Sabyasachi Sengupta, Zahir Abbas, Khushboo Chandra, Subhendu Boral, Aniruddha Maiti, Sangeeta Roy, Angshuman Mukherjee, Arnab Das, Somnath Chakraborty, Pinaki Nag   +11 more
doaj   +1 more source