Results 91 to 100 of about 15,050 (215)

Implantable Drug Delivery Systems for Skeletal Muscles and Eyes

Advanced NanoBiomed Research, Volume 6, Issue 2, February 2026.
This review highlights the different types of recent implantable drug delivery systems (IDDS) fabricated for a use with skeletal muscles, and with eyes. It presents the developments already made and the current research directions, showing the evolution of IDDS and their great diversity.
Serge Ostrovidov, Murugan Ramalingam, Hongkai Wu, Toshinori Fujie, Yukinari Nakamura, Takeshi Hori, Yuji Nashimoto, Xuetao Shi, Hirokazu Kaji   +8 more
wiley   +1 more source

Systemic counterregulatory response of angiopoietin‐2 after aflibercept therapy for nAMD: a potential escape mechanism

Acta ophthalmologica, 2020
To analyse the effect of intravitreal aflibercept injections on systemic angiopoietin‐2 (Ang2) and vascular endothelial growth factor (VEGF)‐A levels in patients with neovascular age‐related macular degeneration (nAMD).
Reinhard Angermann, Teresa Rauchegger, Yvonne Nowosielski, C. Seifarth, S. Egger, M. Kralinger, G. Kieselbach, C. Zehetner   +7 more
semanticscholar   +1 more source

Distinct Aqueous Humour Cytokine Profiles of Patients with Pachychoroid Neovasculopathy and Neovascular Age-related Macular Degeneration

Scientific Reports, 2018
This study investigated the pathophysiological features of pachychoroid neovasculopathy (PNV) and neovascular age-related macular degeneration (nAMD) by analysing and comparing cytokine profiles in aqueous humour (AH) collected from 18 PNV, 18 nAMD and ...
Nobuhiro Terao, Hideki Koizumi, Kentaro Kojima, Tetsuya Yamagishi, Yuji Yamamoto, Kengo Yoshii, Koji Kitazawa, Asako Hiraga, Munetoyo Toda, Shigeru Kinoshita, Chie Sotozono, Junji Hamuro   +11 more
doaj   +1 more source

Molecular Biomarkers of Neovascular Age-Related Macular Degeneration With Incomplete Response to Anti-Vascular Endothelial Growth Factor Treatment

Frontiers in Pharmacology, 2020
The standard treatment for neovascular age-related macular degeneration (nAMD) consists of intravitreal anti-vascular endothelial growth factors (VEGF).
Irmela Mantel, Angelica Borgo, Jacopo Guidotti, Edwige Forestier, Olga Kirsch, Yasmine Derradji, Patrice Waridel, Frédéric Burdet, Florence Mehl, Claude Schweizer, Raphaël Roduit   +10 more
doaj   +1 more source

Angiogenin, FGF-α, and IL-36β have higher expression levels in aqueous humor of nAMD patients in comparison to cataract patients

BMC Ophthalmology, 2020
Background Numerous cytokines have been proven to participate in the pathogenesis of neovascular age-related macular degeneration (nAMD). The present study aimed to investigate the aqueous humor cytokine expression profile in nAMD patients before and ...
Kailin Chen, Wen Xu, Jiao Zheng, Yupeng Shen, Jian Ma, Zhiqing Chen   +5 more
semanticscholar   +1 more source

Intravitreal anti‐vascular endothelial growth factor injections and risks of stroke in patients with neovascular age‐related macular degeneration—A registry‐based cohort study

Acta Ophthalmologica, Volume 104, Issue 1, Page 98-105, February 2026.
Abstract Background Intravitreal Anti‐Vascular Endothelial Growth Factor (VEGF) rescues retinal vasculatures and prevents disease progression in patients with neovascular Age‐Related Macular Degeneration (nAMD). However, systemic anti‐VEGF may increase the risk of thromboembolic related complications including stroke and TIA. This study aims to explore
A. H. Falemban, K. Söderberg‐Löfdal, F. Jonsson, S. Almlöf‐Sarman, M. von Euler, I. Westborg   +5 more
wiley   +1 more source

Aqueous humor cytokine levels in patients with subretinal fibrosis in neovascular age-related macular degeneration

BMC Ophthalmology
Purpose To investigate aqueous humor cytokine levels in neovascular age-related macular degeneration (nAMD) patients with subretinal fibrosis and to explore the relationship between cytokine levels and disease severity.
Ying Cao, Meijia Dang, Zhen Tian, Tiantian Zhang, Lihua Hou, Min Wang, Shuhui Xing, Yingni Huang, Jing Li   +8 more
doaj   +1 more source

Polypoidal choroidal vasculopathy versus neovascular age related macular degeneration: a comparison of demographics, clinical presentation, and treatment outcomes in Nigerians

JFO Open Ophthalmology
Purpose: To compare the demographics, clinical presentation, and outcomes of intravitreal (IV) anti-VEGF monotherapy in the management of treatment-naïve polypoidal choroidal vasculopathy (PCV) and neovascular age-related macular degeneration (nAMD) in ...
Ogugua Ndubuisi Okonkwo, Adekunle Olubola Hassan, Toyin Akanbi, Chineze Agweye, Arinze Anthony Onwuegbuna   +4 more
doaj   +1 more source

Treat and Extend Treatment Interval Patterns with Anti-VEGF Therapy in nAMD Patients

Vision, 2019
Treat and extend (T&E) is a standard treatment regimen for treating neovascular age-related macular degeneration (nAMD) with anti-vascular endothelial growth factors (anti-VEGFs), but the treatment intervals attained are not well documented.
A. Skelly, V. Bezlyak, G. Liew, E. Kap, A. Sagkriotis   +4 more
semanticscholar   +1 more source

Evaluating Faricimab in Treatment-Naive Neovascular Age Related Macular Degeneration: A Retrospective Analysis of Real-World Data

Clinical Ophthalmology
Danielle Modeste,1 Christopher Stewart,2 Hajani Premanandhan,2 Mahmoud Husseiny Awad,1 Gwyn Samuel Williams1 1Ophthalmology, Singleton Hospital, Swansea Bay University Health Board, Swansea, Wales, UK; 2Swansea Bay University, Medical School, Swansea ...
Modeste D, Stewart C, Premanandhan H, Awad MH, Williams GS   +4 more
doaj