Results 71 to 80 of about 22,786 (211)

Characterizing and assessing vision‐related quality of life among patients discontinued treatment for neovascular age‐related macular degeneration

Acta Ophthalmologica, EarlyView.
Abstract Purpose This study characterized and assessed vision‐related quality of life (VRQoL) in patients with neovascular age‐related macular degeneration (nAMD) who discontinued treatment with intravitreal anti‐vascular endothelial growth factor (anti‐VEGF), comparing them to those undergoing treatment.
Noreddin Shekho, Anna Stage Vergmann, Frederik Nørregaard Pedersen, Lonny Stokholm, Benjamin Sommer Thinggaard   +4 more
wiley   +1 more source

Molecular pathogenesis of subretinal fibrosis in neovascular AMD focusing on epithelial-mesenchymal transformation of retinal pigment epithelium

Neurobiology of Disease, 2023
Age-related macular degeneration (AMD) is a leading cause of vision loss among elderly people in developed countries. Neovascular AMD (nAMD) accounts for more than 90% of AMD-related vision loss.
Dandan Liu, Chaoyang Zhang, Jingting Zhang, Guo-Tong Xu, Jingfa Zhang   +4 more
doaj   +1 more source

Non‐physician delivered intravitreal injection service: A systematic review of safety, implementation, training and patient experience

Acta Ophthalmologica, EarlyView.
Abstract The global demand for intravitreal anti‐vascular endothelial growth factor (anti‐VEGF) therapy continues to rise, straining ophthalmic capacity worldwide. Task shifting from physicians to trained non‐physician healthcare professionals has emerged as a potential strategy to expand service delivery.
Trang Truong Laursen, Haris Bralic, Jakob Grauslund, Yousif Subhi, Lonny Stokholm   +4 more
wiley   +1 more source

Petascale Tcl with NAMD, VMD, and Swift/T [PDF]

2014 First Workshop for High Performance Technical Computing in Dynamic Languages, 2014
Tcl is the original embeddable dynamic language. Introduced in 1990, Tcl has been the foundation of the scripting interface of the popular biomolecular visualization and analysis program VMD since 1995 and was extended to the parallel molecular dynamics program NAMD in 1999.
James C. Phillips, John E. Stone, Kirby L. Vandivort, Timothy G. Armstrong, Justin M. Wozniak, Michael Wilde, Klaus Schulten   +6 more
openaire   +1 more source

The impact of systemic long‐term medications for the development of age‐related macular degeneration

Acta Ophthalmologica, EarlyView.
Abstract Purpose Age‐related macular degeneration (AMD) is a leading cause of central vision loss in the elderly; however, the systemic factors that modulate its incidence and progression remain unclear. We sought to determine whether long‐term use of systemic medications, including diabetes and antithrombotic medications, corticosteroids and ...
Hanna Heloterä, Reijo Sund, Toni Rikkonen, Kai Kaarniranta   +3 more
wiley   +1 more source

Safety and effectiveness of brolucizumab in patients with neovascular age-related macular degeneration: A phase IV study from India

Indian Journal of Ophthalmology
Purpose: The purpose of this study is to evaluate the safety and effectiveness of brolucizumab intravitreal injections (IVI) in Indian patients with neovascular age-related macular degeneration (nAMD).
Asim K Ghosh, Debdulal Chakraborty, Aditya Sudhalkar, Rohan Chawla, Simar R Singh, Atul K Sahu, Ramesh Venkatesh, Vishal Raval, Sonali Shah, Padma Preetha, Maulik Bhavsar, Sandip Patil, Isha Khadke, Anup Thorat   +13 more
doaj   +1 more source

The optical coherence tomography and microperimetry biomarker evaluation in patients with geographic atrophy (OMEGA) study: Geographic atrophy progression in fundus autofluorescence ‐ OMEGA report 3

Acta Ophthalmologica, EarlyView.
Abstract Purpose To measure the progression of geographic atrophy (GA) in subjects with age‐related macular degeneration (AMD) in a natural history study. Methods We analysed fundus autofluorescence (FAF) images using a semiautomatic method (RegionFinder) to quantify the GA area in a monocentric study.
Philippe Valmaggia, Georg Ansari, Nadja Inglin, Nils Schärer, Hanna Zuche, Chrysoula Gabrani, Faady Yahya, Marco Cattaneo, Kristina Pfau, Andrea Giani, Marieh Esmaeelpour, Taffeta Chingning Yamaguchi, Christian Prünte, Hendrik P. N. Scholl, Nicolas Feltgen, Leopold Schmetterer, Maximilian Pfau, Peter M. Maloca   +17 more
wiley   +1 more source

Association of neutrophil-to-lymphocyte ratio and neutrophil activation with treatment response in neovascular AMD

AJO International
Purpose: The neutrophil-to-lymphocyte ratio (NLR) and alterations of activation surface markers on circulating neutrophils have been suggested to be involved in the pathogenesis of age-related macular degeneration (AMD).
Alexander Kai Thomsen, Maria Abildgaard Steffensen, Kathrine Gotfredsen, Henrik Vorum, Bent Honoré, Mogens Holst Nissen, Torben Lykke Sørensen   +6 more
doaj   +1 more source

Modeling elastic properties of polystyrene through coarse-grained molecular dynamics simulations

, 2019
This paper presents an extended coarse-grained investigation of the elastic properties of polystyrene. In particular, we employ the well-known MARTINI force field and its modifications to perform extended molecular dynamics simulations at the $\mu$s ...
Beltukov, Yaroslav, Gula, Igor, Samsonov, Alexander M., Solov'yov, Ilia A.   +3 more
core   +1 more source

Biomathematische Analysen einer CNV bei nAMD

, 2020
Fragestellung: Die OCT-Angiographie (OCT-A) ist eine neue Methode, um nicht-invasiv Gefäßdarstellungen der verschiedenen Gefäßschichten der Makula zu erhalten. Es konnte gezeigt werden, dass die Unterteilung in Typ 1 (okkulte) und Typ 2 (klassische) choroidale Neovaskularisationen[zum vollständigen Text gelangen Sie über die oben angegebene URL]
openaire   +2 more sources