Results 91 to 100 of about 22,786 (211)

Adaptive Ensemble Biomolecular Simulations at Scale

open access: yes, 2019
Recent advances in both theory and methods have created opportunities to simulate biomolecular processes more efficiently using adaptive ensemble simulations.
Balasubramanian, Vivek   +5 more
core   +1 more source

Advances and challenges in multiscale biomolecular simulations: artificial intelligence‐driven paradigm shift

open access: yesQuantitative Biology, Volume 14, Issue 2, June 2026.
Abstract Molecular simulation techniques have become an invaluable tool for elucidating the fundamental principles of life at the molecular level. After nearly five decades of development, biomolecular simulations have evolved to enable the quantitative characterization of complex biomolecular events, such as protein folding, conformational dynamics ...
Wenfei Li, Wei Wang
wiley   +1 more source

Some recent advances in ab initio calculations of nonradiative decay rates of point defects in semiconductors [PDF]

open access: yes, 2019
In this short review, we discuss a few recent advances in calculating the nonradiative decay rates for point defects in semiconductors. We briefly review the debates and connections of using different formalisms to calculate the multi-phonon processes ...
Wang, L
core  

Single-Base DNA Discrimination via Transverse Ionic Transport

open access: yes, 2013
We suggest to discriminate single DNA bases via transverse ionic transport, namely by detecting the ionic current that flows in a channel while a single-stranded DNA is driven through an intersecting nanochannel.
Di Ventra, M., Wilson, James
core   +1 more source

A Cationic Block Co‐Polymer for Gene Delivery in the Posterior Segment of the Eye

open access: yesJournal of Biomedical Materials Research Part A, Volume 114, Issue 5, May 2026.
ABSTRACT Diseases of the back of the eye such as neovascular age‐related macular degeneration (nAMD) are vision threatening and treatment is burdensome for patients, often requiring ocular injections every other month. Injection risks and logistics lower patient compliance; however, even patients receiving optimal treatment can deteriorate.
Amber Monteiro   +8 more
wiley   +1 more source

Distinct Aqueous Humour Cytokine Profiles of Patients with Pachychoroid Neovasculopathy and Neovascular Age-related Macular Degeneration

open access: yesScientific Reports, 2018
This study investigated the pathophysiological features of pachychoroid neovasculopathy (PNV) and neovascular age-related macular degeneration (nAMD) by analysing and comparing cytokine profiles in aqueous humour (AH) collected from 18 PNV, 18 nAMD and ...
Nobuhiro Terao   +11 more
doaj   +1 more source

A Study on Performance and Power Efficiency of Dense Non-Volatile Caches in Multi-Core Systems

open access: yes, 2017
In this paper, we present a novel cache design based on Multi-Level Cell Spin-Transfer Torque RAM (MLC STTRAM) that can dynamically adapt the set capacity and associativity to use efficiently the full potential of MLC STTRAM.
Arjomand, Mohammad   +3 more
core   +1 more source

Decellularized Aged Bruch's Membrane Confers Unique Biochemical Cues to Retinal Pigment Epithelium for In Vitro Modeling of Age‐Related Macular Degeneration

open access: yesAging Cell, Volume 25, Issue 5, May 2026.
A Bruchs membrane (BrM) mimic based on aged decellularized BrM was developed and differentially expressed proteins in aged dECM‐BrM that may provide specific biochemical cues fundamental to model AMD in vitro were identified. RPE culture on aged dECM‐BrM developed certain AMD‐like features including reduced TEER and expression of drusen components ...
Blanca Molins   +8 more
wiley   +1 more source

Real‐world outcomes of aflibercept 8 mg in patients previously treated for neovascular age‐related macular degeneration

open access: yesActa Ophthalmologica, Volume 104, Issue 3, Page 296-304, May 2026.
Abstract Purpose To evaluate visual, anatomical and safety outcomes of aflibercept 8 mg in previously treated patients with neovascular age‐related macular degeneration (nAMD). Methods This retrospective study included nAMD patients switched to aflibercept 8 mg from prior anti‐VEGF therapies at Sahlgrenska University Hospital between February 2024 and ...
Imadeddin Abu Ishkheidem   +5 more
wiley   +1 more source

Polypoidal choroidal vasculopathy versus neovascular age related macular degeneration: a comparison of demographics, clinical presentation, and treatment outcomes in Nigerians

open access: yesJFO Open Ophthalmology
Purpose: To compare the demographics, clinical presentation, and outcomes of intravitreal (IV) anti-VEGF monotherapy in the management of treatment-naïve polypoidal choroidal vasculopathy (PCV) and neovascular age-related macular degeneration (nAMD) in ...
Ogugua Ndubuisi Okonkwo   +4 more
doaj   +1 more source

Home - About - Disclaimer - Privacy