Results 81 to 90 of about 15,547 (188)

Multiscale Modelling of the Electrocatalysis of Microenzymes: Insights Into the Performance of Microperoxidase at an Aqueous/Graphene Interface and Their Exploitation to Improve Performance

Advanced Science, Volume 13, Issue 55, 5 October 2026.
A novel multiscale MD/DFT framework to elucidate microenzyme adsorption and electron transfer is reported. This method reveals distinct configurations for microperoxidase‐11 on graphene and those best suited for electron transfer. Rate constants align with the limited experimental data, establishing this framework as a tool for optimizing microenzyme ...
Milan Mijajlovic, Cheng Hu, Yuhui Sun, Matthew J. Penna, Meisam V. Kiamahalleh, Wenrong Yang, Mark J. Biggs   +6 more
wiley   +1 more source

Increased choroidal stromal volume and altered choriocapillaris perfusion in neovascular AMD: An SS-OCTA association study

Photodiagnosis and Photodynamic Therapy
Purpose: This study aimed to characterize quantitative choroidal metrics using swept-source optical coherence tomography angiography (SS-OCTA) across different stages associated with neovascular age-related macular degeneration (nAMD) and to identify ...
Xuelin Chen, Xuenan Zhuang, Guiqin He, Miaoling Li, Xiongze Zhang, Jiaxin Pu, Yuying Ji, Yining Zhang, Xinlei Hao, Feng Wen   +9 more
doaj   +1 more source

TRAF6 Lactylation in Glycolytic Macrophages Drives NF‐κB Signaling and M1 Polarization During Orthodontic Tooth Movement

Advanced Science, Volume 13, Issue 55, 5 October 2026.
Schematic diagram showing compressive stress triggers glycolytic reprogramming and lactate accumulation in macrophages. Lactate mediates TRAF6 lactylation at K171/K180 dual sites, which enhances its K63‐linked ubiquitination to activate the NF‑κB pathway and promote M1 polarization. This cascade drives orthodontic tooth movement (OTM) and alveolar bone
Xinyi He, Guodong Zhao, Yun Hu, Wenya Bai, Hao Tan, Shuai Yuan, Sihan Yang, Ye Zhu, Xiaohui Xu, Leilei Zheng   +9 more
wiley   +1 more source

Cataract Surgery in nAMD Patients Receiving Intravitreal Aflibercept Injections

Background: To evaluate functional and anatomical outcomesof cataract surgery in neovascular age-related macular neovascularization (nAMD) eyes receiving anti-vascular endothelial growth factor (anti-VEGF) intravitreal injections in modified pro re nata (
Małgorzata Seredyka-Burduk, Grażyna Malukiewicz, Jarosław Kocięcki, Bartlomiej J. Kaluzny, Slawomir Liberski   +4 more
core   +1 more source

Patient Demographics and Baseline Characteristics Among Patients Receiving Ranibizumab or Aflibercept for the Management of nAMD.

, 2015
Patient Demographics and Baseline Characteristics Among Patients Receiving Ranibizumab or Aflibercept for the Management of nAMD.
Jingsong Lu (732560), Fran Milnes (775226), Melvin Olson (775225), Alberto Ferreira (590387), Charles Makin (585729), Alexandros Sagkriotis (775224)   +5 more
core   +1 more source

Radiation damage in serial femtosecond crystallography studied in hemoglobin

Acta Crystallographica Section D, Volume 82, Issue 10, Page 1169-1180, October 2026.
Protein structures determined by serial femtosecond crystallography are indistinguishable when measured with 3 and 10 fs X‐ray pulses, indicating no structural benefit from further shortening the pulse duration under the studied conditions.A central question in macromolecular crystallography is what X‐ray free‐electron laser pulse duration is required ...
Marina Galchenkova, Ibrahim Dawod, Sebastian Cardoch, Janina Sprenger, Dominik Oberthür, Salah Awel, Emiliano De Santis, Oscar Grånäs, Juraj Knoska, Markus Metz, Spencer Passmore, Gisel Pena, Iosifina Sarrou, Max Wiedorn, Nicusor Timneanu, Henry Chapman, Oleksandr Yefanov, Carl Caleman   +17 more
wiley   +1 more source

SRF and SHRM in nAMD: Retrospective Analysis of Visual Prognosis

OBJECTIVE: This study aimed to investigate the correlation between subretinal fluid (SRF) and subretinal hyperreflective material (SHRM) with visual prognosis in neovascular age related macular degeneration (nAMD).
Guo, Huiling, Wu, Weizhen, Wang, Luping, Yang, Ming   +3 more
core   +1 more source

An improved TIGER2 implementation for NAMD suitable for the Blue Gene architecture

, 2019
Here we present an improved implementation of the TIGER2 Replica Exchange Molecular Dynamics (REMD) method, using the replica exchange Application Programming Interface (API) found in contemporary versions of the NAMD Molecular Dynamics Package.
Aaron H. Brown (8093927), Tiffany R. Walsh (771466)   +1 more
core   +1 more source

Insights into the modulation of age‐related macular degeneration: Molecular and systems‐level perspectives

Acta Ophthalmologica, Volume 104, Issue S293, Page S4-S35, October 2026.
ENGLISH SUMMARY In developed countries, age‐related macular degeneration (AMD) is the leading cause of visual impairment in the aging population. Understanding of its pathogenesis is limited and the number of patients is predicted to continue rising. AMD is classified into two main forms: dry and neovascular AMD (dAMD and nAMD, respectively).
Hanna Heloterä
wiley   +1 more source

Recent daily life burdens associated with neovascular age-related macular degeneration involve difficulties in use of electronic devices

Scientific Reports
Neovascular age-related macular degeneration (nAMD) is a prevalent cause of permanent vision loss and blindness in the elderly worldwide, with a significant impact on patients’ daily lives.
Yoko Ozawa, Keisuke Yoshihara, Marwa Mezghani, Paulina Pierzchała, Mateusz Nikodem, Sylvaine Barbier, Mariko Nomoto, Yasuko Aitoku   +7 more
doaj   +1 more source