Results 21 to 30 of about 15,050 (215)
Real-world experience of brolucizumab in nAMD
Indian Journal of Ophthalmology, 2023 Purpose: To evaluate real-world outcomes with neovascular age-related macular degeneration (nAMD) in relation to anatomical success, visual outcomes, and safety of intravitreal brolucizumab (IVBr) injection at 1.5 years. Methods: Prospective, randomized, single-center study between ...
Shilpi H Narnaware +3 more
openaire +3 more sources
AMBERff at Scale: Multimillion-Atom Simulations with AMBER Force Fields in NAMD
bioRxiv, 2023 All-atom molecular dynamics (MD) simulations are an essential structural biology technique with increasing application to multimillion-atom systems, including viruses and cellular machinery.
Santiago Antolínez +3 more
semanticscholar +1 more source
Neovascular Age-Related Macular Degeneration (nAMD): A Review of Emerging Treatment Options
Clinical Ophthalmology, 2022 Neovascular age-related macular degeneration (nAMD) is a common world-wide cause of visual loss. Intravitreal anti-vascular endothelial growth factor (anti-VEGF) agents are an effective means to treat nAMD and reduce its impact on vision compared to ...
Colin S H Tan +4 more
semanticscholar +1 more source
Annals of Medicine, 2023 Background/objectives Neovascular age-related macular degeneration (nAMD) is a common cause for visual impairment in the ageing population. An increasing number of nAMD patients causes significant health burden, although intravitreal anti-VEGF agents ...
Ida Korva-Gurung +3 more
doaj +1 more source
Implementation of accelerated molecular dynamics in NAMD [PDF]
Computational Science & Discovery, 2011 Accelerated molecular dynamics (aMD) is an enhanced-sampling method that improves the conformational space sampling by reducing energy barriers separating different states of a system. Here we present the implementation of aMD in the parallel simulation program NAMD.
Yi, Wang +3 more
openaire +2 more sources
Integrative metabolome and lipidome analyses of plasma in neovascular macular degeneration
Heliyon, 2023 Age-related macular degeneration (AMD) causes irreversible vision-loss among the elderly in industrial countries. Neovascular AMD (nAMD), which refers to late-stage AMD, is characterized by severe vision-threatening choroidal neovascularization (CNV ...
Tantai Zhao +4 more
doaj +1 more source
Eye, 2022 Introduction In neovascular age-related macular degeneration (nAMD) the exact amount of fluid and its location on optical coherence tomography (OCT) have been defined as crucial biomarkers for disease activity and therapeutic decisions.
L. Coulibaly +7 more
semanticscholar +1 more source
Collective variable-based calculations in NAMD [PDF]
Biophysical Journal, 2009 The computational power of parallel clusters and supercomputers, and of the macromolecular simulation softwares typically used has been rapidly increasing in the recent years. One of the consequences is the higher demand for methods to analyze the dynamics and conformational space of biomolecular complexes.
Fiorin, Giacomo +2 more
openaire +1 more source
BMC Ophthalmology, 2020 Background The concentrations of cytokines in the aqueous humor from neovascular age-related macular degeneration (nAMD) and polypoidal choroidal vasculopathy (PCV) may vary. The study was conducted to compare various cytokine levels in the aqueous humor
Huiying Zhou +3 more
doaj +1 more source
Российский офтальмологический журнал, 2019 Antivasoproliferative therapy is a revolutionary trend in the treatment of neovascular age-related macular degeneration (nAMD), as it is aimed at blocking growth factors of the newly formed vessels.
R. R. Fayzrakhmanov
doaj +1 more source