Results 41 to 50 of about 229,890 (265)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Few-shot Named Entity Ｒecognition for Medical Text
Journal of Harbin University of Science and Technology, 2021 Aiming at the problem that medical text named entity recognition lacks sufficient labeled data，a newly named entity recognition deep neural network and data enhancement method is proposed.
QIN Jian +3 more
doaj +1 more source
Named Data for Mobile AdHoc Networks
, 2016 For the needs of future Internet, many researchers are proposing a paradigm shift towards a new information-centric approach. The Named-Data Networking (NDN) is one these proposals. Instead of addresses, packets should use only names, either expressing interest on specific information or naming the data content carried in.
Pereira, Ana Filipa +4 more
openaire +2 more sources
Network-Layer Trust in Named-Data Networking [PDF]
ACM SIGCOMM Computer Communication Review, 2014 In contrast to today's IP-based host-oriented Internet architecture, Information-Centric Networking (ICN) emphasizes content by making it directly addressable and routable. Named Data Networking (NDN) architecture is an instance of ICN that is being developed as a candidate next-generation Internet architecture.
Cesar Ghali, Gene Tsudik, Ersin Uzun
openaire +1 more source
NDNTP: A Named Data Networking Time Protocol [PDF]
IEEE Network, 2020 Named Data Networking (NDN) architectural features, including multicast data delivery, stateful forwarding, and in-network data caching, have shown promise for applications such as video streaming and file sharing. However, collaborative applications, requiring a multi-producer participation introduce new NDN design challenges.
Mtibaa, Abderrahmen +1 more
openaire +3 more sources
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
International Journal of Distributed Sensor Networks, 2020 Vehicle ad hoc network is the key technology for a future Internet of vehicles and intelligent transport system. However, involvement of vast number of vehicles in Internet of vehicles limits the performance of vehicle ad hoc network.
Mazen Alowish +4 more
doaj +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
IEEE AccessThe fundamental objective of the Internet of Things (IoT) and Named Data Networking (NDN) architectures is to facilitate the provision of communication services.
Yahui Meng +2 more
doaj +1 more source