Results 61 to 70 of about 773,104 (270)

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Equivalence class formation in 11-month-old pre-linguistic infants

Acta Colombiana de Psicología
Several studies have attempted to assess the role of naming in the emergence of equivalence relations, but results are inconsistent; on the one hand, there are reports of equivalence emerging without naming and on the other hand, some authors claim that ...
Adriana Gabriela Quezada Velázquez, María Antonia Padilla Vargas, Carlos Javier Flores Aguirre   +2 more
doaj   +1 more source

Noms, étiquette(s) et identités dans Persuasion, de Jane Austen

Cahiers Victoriens et Edouardiens, 2014
Jane Austen’s last novel, Persuasion, dramatises the tensions inherent in the decline of the ancient landed order and of its traditional sources of authority, as the emergence of a new social hierarchy, in the wake of the Napoleonic wars, was leading to ...
Marie-Laure Massei
doaj   +1 more source

Survey-based naming conventions for use in OBO Foundry ontology development [PDF]

, 2009
A wide variety of ontologies relevant to the biological and medical domains are available through the OBO Foundry portal, and their number is growing rapidly.
Chris, F., Daniel, Schober, E. Kusnierczyk, Lomax, Waclaw, Mungall, Jane, Philippe, Rocca-Serra, Smith, Barry, Susanna-Assunta, Sansone, Suzanna, Lewis, Taylor, Chris   +9 more
core  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Ensino de Nomeação com Objetos e Figuras para Crianças com Autismo

Psicologia: Teoria e Pesquisa
Resumo Este estudo comparou a utilização de estímulos bidimensionais e tridimensionais em um procedimento de instrução com múltiplos exemplares para instalar nomeação (integração dos repertórios de falante e ouvinte) em quatro crianças com autismo.
Edson Luiz Nascimento dos Santos, Carlos Barbosa Alves de Souza   +1 more
doaj   +1 more source

The Pragmatics of Naming in Samuel Richardson’s Clarissa

E-REA, 2013
Samuel Richardson’s Clarissa thematizes the name and the associated naming process. Destined to change her name by marrying Solmes, the eponymous heroine uses several borrowed names in her flight.
Christophe LESUEUR
doaj   +1 more source

Dissociating word frequency and age of acquisition: The Klein effect revived (and reversed). [PDF]

, 2006
The Klein effect (G. S. Klein, 1964) refers to the finding that high-frequency words produce greater interference in a color-naming task than low-frequency words.
Barry, Christopher, Dewhurst, Stephen A.
core   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source