Results 131 to 140 of about 15,085 (211)

Targeting NAMPT‐OPA1 for treatment of senile osteoporosis

open access: yesAging Cell
AbstractSenescence of bone marrow mesenchymal stem cells (BMSCs) impairs their stemness and osteogenic differentiation, which is the principal cause of senile osteoporosis (SOP). Imbalances in nicotinamide phosphoribosyltransferase (NAMPT) homeostasis have been linked to aging and various diseases.
Chao‐wen Bai   +9 more
openaire   +2 more sources

Washington University Record, November 29, 2007 [PDF]

open access: yes, 2007
https://digitalcommons.wustl.edu/record/2126/thumbnail ...

core   +1 more source

Eicosapentaenoic acid stimulates AMP-activated protein kinase and increases visfatin secretion in cultured murine adipocytes [PDF]

open access: yes, 2009
Visfatin is an adipokine highly expressed in visceral AT (adipose tissue) of humans and rodents, the production of which seems to be dysregulated in excessive fat accumulation and conditions of insulin resistance. EPA (eicosapentaenoic acid), an n−3 PUFA
Bustos, M. (Matilde)   +4 more
core  

Mechanisms of resistance to NAMPT inhibitors in cancer

open access: yesCancer Drug Resistance
A common barrier to the development of effective anticancer agents is the development of drug resistance. This obstacle remains a challenge to successful clinical translation, particularly for targeted agents. Nicotinamide phosphoribosyltransferase (NAMPT) inhibitors represent a clinically applicable drug class that exploits the increased dependence of
Jansen Redler   +2 more
openaire   +2 more sources

Circulating levels of novel adipocytokines in patients with colorectal cancer [PDF]

open access: yes, 2011
Objective: Adipocytokines have been reported to contribute to the pathogenesis of colorectal cancer (CRC). The aim of this matched case-control study was to explore circulating novel adipocytokines, such as serum visfatin, omentin-1 and vaspin levels ...
Akbarzadeh, Samad   +6 more
core  

Celebration Schedule 2015 (Friday)

open access: yes, 2015
Full presentation schedule for Celebration, Friday, May 1 ...
Provost\u27s Office,
core  

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