Results 61 to 70 of about 7,734 (200)

Linking telemetry data with forage availability maps advances information for moose management

open access: yesWildlife Biology, EarlyView.
Evidence‐based forest and wildlife management requires precise estimates of forage availability for spatial planning and conflict mitigation. Recently, novel datasets and associated maps have been developed for use in Swedish forest and wildlife management.
Lukas Graf   +3 more
wiley   +1 more source

Hormone Replacement Therapy for Menopausal Symptoms and the Risk of Cardiometabolic Disease: Current Evidence and Future Directions

open access: yesBJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Background The transition through menopause is accompanied by a series of adverse metabolic changes which are associated with an increased risk of cardiometabolic disease, a major cause of mortality in women after midlife. Whilst the indication for menopausal hormone replacement therapy (HRT) is the control of menopausal symptoms ...
Jiawen Dong   +5 more
wiley   +1 more source

An integrated new approach methodology for inhalation risk assessment of safe and sustainable by design nanomaterials

open access: yesEnvironment International
The production and use of nanomaterials (NMs) has increased over the last decades posing relevant questions on their risk after release and exposure of the population or sub-populations. In this context, the safe and sustainable by design (SSbD) approach
Giulia Motta   +7 more
doaj   +1 more source

NMDA receptor subunit‐dependent analysis of radiprodil inhibition in neonatal male rat substantia nigra dopaminergic neurons

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Radiprodil is a GluN2B subunit selective NMDA receptor negative allosteric modulator which is currently under clinical investigation as a possible anti‐epileptic drug for paediatric use. Our goal was to investigate the inhibition of dopaminergic neuron NMDA responses by radiprodil.
Bangyuan Liu, Alasdair J. Gibb
wiley   +1 more source

The DIKW of Transcriptomics in Ecotoxicology: Extracting Information, Knowledge, and Wisdom From Big Data

open access: yes
Environmental Toxicology and Chemistry, EarlyView.
Jessica A. Head   +2 more
wiley   +1 more source

Interaction with NEGR1 affects mGlu5 cell signalling and the neuroprotection induced by the positive allosteric modulator VU0409551

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose The metabotropic glutamate receptor mGlu5 plays an important role in neuronal survival and synaptic plasticity. We and others have shown that mGlu5 positive allosteric modulators (PAMs) are biased agonists, triggering the activation of neuroprotective pathways and promoting neuronal survival. As mGlu5 biased pharmacology
Jennifer D. S. Guimaraes   +14 more
wiley   +1 more source

New approach methodologies in human health risk assessment across European regulatory frameworks: Status quo, barriers and drivers for regulatory acceptance and use

open access: yesEnvironment International
The traditional approaches to chemical risk assessment for human health are continuously challenged by their limitations, such as validity concerns, societal pressure to use animal-free methods, and resource constraints. New Approach Methodologies (NAMs)
Angela Bearth   +11 more
doaj   +1 more source

ÄSTHETIK DES JIDDISCHEN IN DER KLASSISCHEN MODERNE

open access: yesGerman Life and Letters, EarlyView.
ABSTRACT Der Beitrag erzählt die Geschichte der Entdeckung und Aufwertung des Jiddischen unter deutschsprachigen Schriftstellerinnen und Schriftstellern. Hatte die zunächst als Judendeutsch, Mauscheln oder Jargon bezeichnete Sprache in literarischen Texten des 19. Jahrhunderts vornehmlich eine mimetische Funktion, in der Regel wie bei Gustav Freytag in
Alexander Nebrig
wiley   +1 more source

Equitable education for migrant students? Investigating the educational success of newly arrived migrants in Flanders

open access: yesFrontiers in Education
IntroductionPrevious research has uncovered various inequalities for immigrant students in education systems worldwide. Yet, the degree to which diverse background factors, such as socio-economic status and prior educational trajectory, contribute to ...
Shauny Seynhaeve   +3 more
doaj   +1 more source

Advances in organic UV filters for sunscreens over the past decade

open access: yesPhotochemistry and Photobiology, EarlyView.
Highlighted organic UV filter frameworks that have been described for sunscreens over the past decade divided into three groups: derivatives of or inspired by approved organic UV filters, natural product‐based compounds, and miscellaneous. Abstract Ultraviolet (UV) radiation is a major environmental factor in photoaging, erythema, and skin cancer ...
Gabriela Zanella Marcon   +4 more
wiley   +1 more source

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