Nandrolone decanoate-induced hypogonadism in male rats: Dose- and time-dependent effects on pituitary and testicular hormonal functions. [PDF]
Physiol RepImpacts of nandrolone decanoate (ND) were studied on pituitary‐testis axis in male rats, and compared with testosterone enanthate (TE). Results show ND‐ or TE‐induced hypogonadism coincided with inhibition of T biosynthesis, and suggest disruption of T negative feedback on pituitary. The testes showed histopathological defects in both ND and TE treated
Karimi S +5 more
europepmc +3 more sources
Effects of Nandrolone Decanoate on Skeletal Muscle and Neuromuscular Junction of Sedentary and Exercised Rats [PDF]
Medicina, 2023 Background and Objectives: Nandrolone decanoate (ND) is the most widely used among the anabolic androgenic steroids (AAS), synthetic substances derived from testosterone, to improve muscular and health gains associated with exercises.
Felipe Cantore Tibúrcio +8 more
doaj +3 more sources
Effects of nandrolone decanoate on telomere length and clinical outcome in patients with telomeropathies: a prospective trial [PDF]
Haematologica, 2022 Androgens have been reported to elongate telomeres in retrospective and prospective trials with patients with telomeropathies, mainly with bone marrow failure. In our single-arm prospective clinical trial (clinicaltrials gov.
Diego V. Clé +12 more
doaj +3 more sources
Nandrolone decanoate: new therapeutic option for telomeropathies? [PDF]
Haematologica, 2023 Not available.
Camilla Frieri
doaj +3 more sources
Simple and Accurate HPTLC-Densitometric Method for Assay of Nandrolone Decanoate in Pharmaceutical Formulation [PDF]
Molecules, 2019 This study reports the development and validation of a new, simple, and accurate high-performance thin-layer chromatography (HPTLC)-densitomeric method for the determination of nandrolone decanoate in a commercially available injection formulation ...
Małgorzata Dołowy +2 more
doaj +2 more sources
The Impact of Nandrolone Decanoate in the Osseointegration of Dental Implants in a Rabbit Model: Histological and Micro-Radiographic Results. [PDF]
Materials (Basel), 2021 Despite high rates of osseointegration in healthy patients, complex cases present an increased risk of osseointegration failure when treated with dental implants.
Lupi SM +3 more
europepmc +3 more sources
Effects of local nandrolone decanoate on TGF-1β and IGF-1 in the healing of the muscle wound [PDF]
Iraqi Journal of Veterinary Sciences, 2023 Identifying the appropriate therapy for the problem of exposure to muscular wounds is an essential issue in people and in animals, especially racing animals such as horses, in whom muscular function is part of life. This study investigates the hypothesis
Tamarah M. Al-Abdullah +1 more
doaj +2 more sources
Nandrolone decanoate administration does not attenuate muscle atrophy during a short period of disuse. [PDF]
PLoS ONE, 2019 BACKGROUND:A few days of bed rest or immobilization following injury, disease, or surgery can lead to considerable loss of skeletal muscle mass and strength.
Astrid M H Horstman +10 more
doaj +2 more sources
PDE7B is involved in nandrolone decanoate hydrolysis in liver cytosol and its transcription is up-regulated by androgens in HepG2 [PDF]
Frontiers in Pharmacology, 2014 Most androgenic drugs are available as esters for a prolonged depot action. However the enzymes involved in the hydrolysis of the esters have not been identified.
Emmanuel eStrahm +2 more
doaj +2 more sources
Simplified Analysis of Native Steroid Esters in Dried Blood Spots by LC-MS<sup>3</sup>. [PDF]
J Mass SpectromABSTRACT Steroidal esters (e.g., testosterone, nandrolone and boldenone esters) belong to the substance class prohibited in professional sport that is particularly frequently abused due to its considerable performance‐enhancing effects. Thus, a high number of adverse analytical findings in doping controls is reported every year.
Thomas A +3 more
europepmc +2 more sources