Results 51 to 60 of about 193 (127)

A Comparative Study of Nandrolone Decanoate and Whey Protein Effects on the Frontal Cerebral Cortex of Adult Male Albino Rats Using Histological, Biochemical, and Immunohistochemical Techniques

The Egyptian Journal of Histology
Background: Nandrolone decanoate and whey protein are widely used by athletes and bodybuilders to enhance muscle mass and performance. While the neurotoxic effects of anabolic-androgenic steroids have been extensively investigated, the cerebral ...
Noha Gaber, Walaa Elfakhharany, Nouran Olama, Shaimaa Magdy   +3 more
doaj   +1 more source

A novel treatment strategy targeting cellular pathways with natural products to alleviate sarcopenia

Phytotherapy Research, Volume 38, Issue 11, Page 5033-5051, November 2024.
Schematic overview of the possible therapeutic mechanisms involved in sarcopenia with various natural products. The global rise in aging populations has led to an increased prevalence of sarcopenia, which is becoming a new social issue. Currently, there is no FDA‐approved treatment for sarcopenia; however, ongoing studies are identifying diverse ...
Da Hee Lee, Hye Jin Lee, Gabsik Yang, Dae Yong Kim, Jong Uk Kim, Tae Han Yook, Jun Ho Lee, Hong Jun Kim   +7 more
wiley   +1 more source

Nandrolone decanoate–induced hypogonadism in male rats: Dose‐ and time‐dependent effects on pituitary and testicular hormonal functions

Physiological Reports, Volume 12, Issue 19, October 2024.
Impacts of nandrolone decanoate (ND) were studied on pituitary‐testis axis in male rats, and compared with testosterone enanthate (TE). Results show ND‐ or TE‐induced hypogonadism coincided with inhibition of T biosynthesis, and suggest disruption of T negative feedback on pituitary. The testes showed histopathological defects in both ND and TE treated
Sholeh Karimi, Negar Kazori, Sayyed Mohammad Hadi Alavi, Sara Alijanpour, Mohammad Alim Atif Siddiqi, Bahman Zeynali   +5 more
wiley   +1 more source

Advent of oral medications for the treatment of hereditary angioedema

Clinical and Translational Allergy, Volume 14, Issue 9, September 2024.
Abstract Background Hereditary angioedema (HAE) is a rare genetic disorder characterized by unpredictable, debilitating episodes of submucosal and/or subcutaneous tissue swelling, which may be life‐threatening depending on anatomic location. The two primary management strategies for HAE are ready access to effective on‐demand treatment in all patients ...
Anna Valerieva, Teresa Caballero, Markus Magerl, Joao P. Frade, Paul K. Audhya, Timothy Craig   +5 more
wiley   +1 more source

Androgen abuse: Risks and adverse effects in men

Annals of the New York Academy of Sciences, Volume 1538, Issue 1, Page 56-70, August 2024.
Androgens, formerly known as anabolic‐androgenic steroids, mimic the effects of testosterone and are being increasingly abused for non‐medical purposes such as body and performance enhancement. Androgen abuse is associated with increased mortality, and multi‐system adverse effects have been reported, including cardiovascular toxicity, infertility ...
Bonnie Grant, Elizabeth Hyams, Rhianna Davies, Suks Minhas, Channa N. Jayasena   +4 more
wiley   +1 more source

Single and multi‐dose pharmacology of recombinant and urinary human chorionic gonadotrophin in men

Clinical Endocrinology, Volume 101, Issue 1, Page 42-50, July 2024.
Abstract Objective Human choriogonadotrophin (hCG) treatment of gonadotrophin‐deficient infertile men uses hCG of urinary (uhCG) or recombinant (rhCG) origin, but these treatments have not been compared nor are there studies defining rhCG dosing in men.
David J. Handelsman, Amanda Idan, Reena Desai, Janelle Grainger, Catrin Goebel, Sue Sleiman, Sasha Savkovic, Dorothy Kouzios, Venna Jayadev, Ann J. Conway   +9 more
wiley   +1 more source

Targeted and untargeted metabolomics and lipidomics in dried blood microsampling: Recent applications and perspectives

Analytical Science Advances, Volume 5, Issue 5-6, June 2024.
Abstract Blood microsampling (BµS) offers an alternative to conventional methods that use plasma or serum for profiling human health, being minimally invasive and cost effective, especially beneficial for vulnerable populations. We present a non‐systematic review that offers a synopsis of the analytical methods, applications and perspectives related to
Pauline Couacault, Dennisse Avella, Sara Londoño‐Osorio, Ana S. Lorenzo, Ana Gradillas, Olli Kärkkäinen, Elizabeth Want, Michael Witting   +7 more
wiley   +1 more source

Effect of Nandrolone Decanoate on Serum Lipoprotein (a) and its isoforms in hemodialysis patients

Lipids in Health and Disease, 2004
Malnutrition, anemia and increased atherosclerosis are the main causes of mortality in hemodialysis patients. Therapies designed to improve the disorders might therefore be expected to improve outcome.
Rohbaninoubar Mohammad, Argani Hassan, Ghorbanihaghjo Amir, Rashtchizadeh Nadereh   +3 more
doaj   +1 more source

Nandrolone alters the behavioral response to cocaine as well as striatal and cortical dopamine receptors of prepubertal male rats

Scientific Reports
Nandrolone, is an anabolic androgenic steroid (AAS) used by adolescents and young adults. Supraphysiologic doses of AAS are correlated with dysfunctions in anxiety and reward.
Jaime A. Freire-Arvelo, Carlos J. Rivero, Iván G. Santiago-Marrero, Andrea Mendez-Morales, Amanda J. González-Segarra, Enrique U. Pérez-Cardona, Ricardo J. Torres-Ramirez, Annabell C. Segarra   +7 more
doaj   +1 more source

Adverse effects of consumption of anabolic steroids on heart: An Experimental Study [PDF]

Journal of Research in Applied and Basic Medical Sciences
Background & Aims:  One of the most popular Anabolic Androgenic Steroids (AAS) among athletes and teenagers is Nandrolone Decanoate (ND), a synthetic testosterone analog.
Parvaiz Ahmad Lone, Mudasir Ahmad Khan, Yunis Parveiz Malik   +2 more
doaj