Results 51 to 60 of about 19,077 (260)

Development of a Novel Methotrexate-Loaded Nanoemulsion for Rheumatoid Arthritis Treatment with Site-Specific Targeting Subcutaneous Delivery

Nanomaterials, 2022
Rheumatoid arthritis (RA) is a systemic, chronic autoimmune disease that causes disability due to progressive inflammation and destruction of the tissues around the joints.
Parvathy Suresh, Mounir M. Salem-Bekhit, Hafsa Palathum Veedu, Sultan Alshehri, Sreeja Chandrasekhar Nair, Sarah I. Bukhari, Vidya Viswanad, Ehab I. Taha, Ram Kumar Sahu, Mohammed M. Ghoneim, Ibrahim Elbagory   +10 more
doaj   +1 more source

The Cancer Cell Metabolic Reprogramming Remodels the Tumor Microenvironment: Molecular Mechanisms and Therapeutic Strategies

Advanced Science, EarlyView.
This review elucidates how cancer cell metabolic reprogramming—across glucose, lipid, amino acid, and nucleotide pathways—remodels the tumor microenvironment to suppress anti‐tumor immunity and promote immune escape. Targeting these metabolic axes offers promising strategies to overcome immunotherapy resistance and enhance cancer treatment.
Guoqing Xiang, Zhicheng Zhou, Xue Jiang, Zhenguang Du, Yangyang Zhan, Xinli Liu   +5 more
wiley   +1 more source

Development of triptolide-nanoemulsion gels for percutaneous administration: physicochemical, transport, pharmacokinetic and pharmacodynamic characteristics

Journal of Nanobiotechnology, 2017
Background This work aimed to provide useful information on the use of nanoemulsions for the percutaneous administration of triptolide. Lipid nanosystems have great potential for transdermal drug delivery.
Meng Yang, Yongwei Gu, Dishun Yang, Xiaomeng Tang, Jiyong Liu   +4 more
doaj   +1 more source

Assessment of the antibacterial effects of cinnamon essential oil and its nanoemulsion on some normal flora bacteria in the skin, gills, and rearing water of rainbow trout [PDF]

تحقیقات دامپزشکی و فرآورده‌های بیولوژیک
Introduction: Considering the role of normal flora bacteria in the high perishability of rainbow trout, natural antimicrobial agents have attracted attentions as alternatives to synthetic preservatives.
Roya Soltaninejad, Ashraf Kariminik
doaj   +1 more source

Synergistic Effect on Enhanced Oil Recovery in High Salinity Carbonate Reservoirs Using a Novel PEI‐Functionalized Carbon Nanotube Nanocomposite

Asia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT Enhancing oil recovery (EOR) in mature reservoirs is hindered by high interfacial tension (IFT) and oil‐wet rock formations, especially under harsh, high‐salinity conditions. This study aims to overcome these limitations by synthesizing a novel carbon nanotube nanocomposite covalently grafted with polyethylenimine and non‐covalently ...
Mohamed Abu Shuheil, Dilipkumar S. Patel, N. Beemkumar, Tariq Abdulkader Alrihaim, Dhirendra Nath Thatoi, Ripendeep Singh, Rohit Kumar, Parminder Singh, Ahmad Khalid   +8 more
wiley   +1 more source

Impact of nanoemulsion of Ajwain-cardamom essential oils on Mortadella sausage quality during chilling (4°C) storage

Heliyon
Essential oils application as natural preservatives is challenging owning to low solubility and stability to harsh conditions, while incorporation of essential oils into nanoemulsion systems can effectively improve these issues.
Elmira Taherzadeh, Akram Arianfar, Elham Mahdian, Sharareh Mohseni   +3 more
doaj   +1 more source

Tackling cancer stemness with nanotechnology in the era of precision medicine

BMEMat, EarlyView.
Precise customization of nanoparticles (NPs) enables active targeting of cancer stem cells (CSCs), thereby improving drug delivery and therapeutic efficacy. NP‐based probing enhances CSC detection through imaging and liquid biopsy, whereas diverse therapeutic payloads improve therapeutic outcomes.
Shaolei Guo, Shun Yao, Lihui Meng, Chunyuan Chen, Yuechu Lucinda Lu, Rong Lu, Kashif Rafiq Zahid, Umar Raza, Qingzhi Wu, Wenli Chen   +9 more
wiley   +1 more source

OPTIMIZATION AND EVALUATION OF TOPICAL KETOCONAZOLE NANOEMULSION [PDF]

, 2018
 Objective: The present study is to formulate and optimization of surfactant, cosurfactant, and oil of ketoconazole nanoemulsion.Methods: Ketoconazole was dissolved in surfactant, cosurfactant, and oil until saturated, clear solution extracted with ...
Ramlan Sinaga, Kasmirul, Masfria, Masfria, Ernoviya, Ernoviya   +2 more
core   +3 more sources

Fabrication, in-vitro characterization, and enhanced in-vivo evaluation of carbopol-based nanoemulsion gel of apigenin for UV-induced skin carcinoma

Drug Delivery, 2017
The aim of this study was to develop a potential novel formulation of carbopol-based nanoemulsion gel containing apigenin using tamarind gum emulsifier which was having the smallest droplet size, the highest drug content, and a good physical stability ...
Manmohan S. Jangdey, Anshita Gupta, Swarnlata Saraf   +2 more
doaj   +1 more source

Bridging the translational gap in clinical nanomedicine: From rational design to clinical reality

BMEMat, EarlyView.
Nanotechnology offers a multi‐faceted approach to modern healthcare, encompassing high‐sensitivity diagnostic imaging, innovative vaccine delivery, and targeted therapeutics. This review explores how these nanomedicine applications address critical challenges in cancer recurrence and the treatment of neurologic and respiratory diseases to combat rising
Ahmed H. Ghonaim, Marwa Ahmed El‐Naka, Wedad M. Nageeb, Atta Ullah Khan, Noura M. Seleem, Aliaa Abdelghafar, Doaa Zamel, Yang Liu, Qigai He, Wentao Li   +9 more
wiley   +1 more source