Results 61 to 70 of about 11,633 (215)

Mitochondria‐targeted nanomedicine for cancer therapy: Targeting strategies, therapeutic mechanisms, and translational challenges

Interdisciplinary Medicine, EarlyView.
This review highlights recent advances in mitochondria‐targeted nanomedicine for cancer therapy. It summarizes key targeting strategies and delineates four principal therapeutic mechanisms: oxidative stress–induced mitochondrial dysfunction, disruption of energy metabolism, direct mitochondrial damage, and induction of immunogenic cell death.
Linfeng Xiao, Xiaowei Chang, Jun Zhang, Yinshan Hong, Wenhui Cao, Zhewu Zhao, Yu‐E. Wang, Yanling Yang   +7 more
wiley   +1 more source

Nanostructured lipid carriers and natural deep eutectic solvents: a highly advantageous combination for the encapsulation of curcumin

Journal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKGROUND Curcumin is a naturally derived polyphenol known for its potent biological properties. Its therapeutic potential, however, is hindered by low bioavailability. Nanostructured lipid carriers (NLCs) have emerged as advanced delivery systems to overcome such limitations. Natural deep eutectic solvents (NADESs) have garnered attention as
Kyriaki Safari, Ioanna Pitterou, Marianthi Miliaronikolaki, Nikolaos Paraskevopoulos, Andromachi Tzani, Anastasia Detsi   +5 more
wiley   +1 more source

Punicalagin‐enriched edible coatings from revalorized pomegranate peels for quality enhancement of fresh‐cut celery

Journal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND Pomegranate peel is a rich source of phenolics, particularly punicalagin, but its valorization for fresh produce preservation requires stabilization. This study aimed to develop and evaluate freeze‐dried encapsulates of pomegranate peel extracts as ingredients in edible coatings for fresh‐cut celery. Pomegranate peels were extracted
Lorena Martínez‐Zamora, Rosa Zapata, Marina Cano‐Lamadrid, Francisco Artés‐Hernández   +3 more
wiley   +1 more source

Ultrasonic emulsification of Cananga odorata nanoemulsion formulation for enhancement of herbicidal potential

Scientific Reports
A nanoemulsion was fabricated from Cananga odorata essential oil (EO) and stabilized by incorporation of Tween 80 using ultrasonication. The major constituents of the EO were benzyl benzoate, linalool, and phenylmethyl ester.
Chamroon Laosinwattana, Naphat Somala, Jantra Dimak, Montinee Teerarak, Nawasit Chotsaeng   +4 more
doaj   +1 more source

Activity of A Nanoparticles Preparation Containing Watermelon Peel Extract and Kepok Banana Peel on Ureum and Creatinine Levels in Urolitogenesis Mice [PDF]

BIO Web of Conferences
Kidney stones are one of the causes of chronic kidney failure that can cause long-term complications. Kepok banana peel and yellow watermelon peel are still rarely used as medicine.
Hidayati Titiek, Mahanggoro TriPitara, Indrayanti Indrayanti, Habibah Khalisha Diaz, Lutfi Dzaka Ogan Amirudin, Syifa Amira Kumala, Tamimi Nia Thosimomia, Akrom Akrom, Tsai Prof Mei LIn   +8 more
doaj   +1 more source

Metabolomics‐based study of the preservation mechanism of a tea saponin–cinnamaldehyde nanoemulsion applied to Xinyu tangerines

Journal of the Science of Food and Agriculture, EarlyView.
Abstract Background The Xinyu tangerine is a geographical indication agricultural product from Jiangxi province, China. During postharvest storage, nutrient loss and pathogen‐induced decay reduce fruit quality. The selection of appropriate preservatives is therefore important for maintaining postharvest quality.
Yan Leng, Xinjian Gao, Yichen Zhang, Zehang Yan, Wanyi Chen, Yang Huang, Xiaoxia Zuo, Liqin Zhu, Zhipeng Cai, Jing Wang, Yonggen Shen   +10 more
wiley   +1 more source

Formulation and characterization of Cefuroxime Axetil nanoemulsion for improved bioavailability

Journal of Pharmacy and Bioallied Sciences, 2012
Cefuroxime Axetil nanoemulsion was formulated to address the problem of poor oral bioavailability. Formulation was manufactured utilizing Capmul MCM, Soya lecithin, Deoxycholic acid, Pluronic F127 and distilled water.
Yomesh Patel, Aditi Poddar, Krutika Sawant   +2 more
doaj   +1 more source

Crystalline Poly(L‐Lactic Acid) Nanoparticles via Nonsolvent‐Induced Cascade Phase Separation

Journal of Polymer Science, EarlyView.
Water is used as the nonsolvent to induce liquid/liquid phase separation (LLPS) of poly(L‐lactic acid) (PLLA)/propylene carbonate solution and PLLA crystallization. Due to the two levels of cascade LLPS coupled with confined PLLA crystallization, three types of polymeric nanoparticles, including PLLA single crystals, Ouzo crystalsomes, and sheaf‐like ...
Niloofar Esmati, Shichen Yu, Carl T. Furner, Christopher Y. Li   +3 more
wiley   +1 more source

Anti-inflammatory effects of intravenous methotrexate associated with lipid nanoemulsions on antigen-induced arthritis

Clinics, 2016
OBJECTIVE: To test the hypothesis that intravenous use of methotrexate associated with lipid nanoemulsions can achieve superior anti-inflammatory effects in the joints of rabbits with antigen-induced arthritis compared with commercial methotrexate ...
Suzana B.V. Mello, Elaine R. Tavares, Maria Carolina Guido, Eloisa Bonfá, Raul C. Maranhão   +4 more
doaj   +1 more source

Baicalein Sensitizes Radioresistant BT549 and MCF7‐R Breast Cancer Cells by Modulating Rac1 Signaling

Phytotherapy Research, EarlyView.
ABSTRACT Radioresistance remains a key barrier in breast cancer (BC) treatment. Baicalein, a flavonoid from Scutellaria baicalensis, has shown potential to enhance radiosensitivity. This study investigates its efficacy and mechanism in radioresistant BC models. Radioresistant BC cell models were established via fractionated irradiation and validated by
Zitong Zhao, Zhangyun Li, Quanzhou Peng, Shuqun Zhang   +3 more
wiley   +1 more source