The present study focused on the fabrication of berberine sodium alginate nanoparticles with a combination approach of conventional nanoprecipitation method with ionic complexation to improve its poor water solubility. The optimization of nanoformulation
Meenakshi Mehra +6 more
doaj +2 more sources
A Huaxian Formula Nanoformulation Confers Protection Against Acute Radiation-Induced Lung Injury by Targeting Ferroptosis. [PDF]
An inhalable, nanoengineered herbal therapy achieves protection against acute radiation‐induced lung injury via self‐assembled nanomicelle‐mediated pulmonary targeting and a previously unrecognized dual mechanism that attenuates oxidative stress while inhibiting ferroptosis in alveolar epithelial cells.
Quan L +11 more
europepmc +2 more sources
Biological activity In vitro, absorption, BBB penetration and tolerability of nanoformulation of BT44, a RET agonist with disease-modifying potential for the treatment of neurodegeneration [PDF]
BT44 is a novel, second generation glial cell line-derived neurotropic factor (GDNF) mimetic, with improved biological activity and a lead compound for the treatment of neurodegenerative disorders.
Yulia , Sidorova +7 more
core +2 more sources
Antioxidant and Antidiabetic Properties of a Thinned-Nectarine-Based Nanoformulation in a Pancreatic β-Cell Line [PDF]
Pancreatic β-cells play a crucial role in maintaining glucose homeostasis, although they are susceptible to oxidative damage, which can ultimately impair their functionality.
Gian Carlo Tenore +8 more
core +1 more source
Nanoformulations for molecular MRI [PDF]
AbstractNanoscale contrast agents have shown the ability to increase the detection sensitivity of magnetic resonance imaging (MRI) by several orders of magnitude, endowing this traditionally macroscopic modality with the ability to observe unique molecular signatures.
Chuqiao, Tu, Angelique Y, Louie
openaire +2 more sources
Recent Advances in Sorafenib based Nanoformulation for Enhanced Cancer Therapy [PDF]
Sorafenib, a multi-kinase inhibitor has gained significant attention in cancer therapy. However, the clinical use of sorafenib is limited by poor aqueous solubility, low bioavailability, unfavorable pharmacokinetic properties, and undesirable side ...
Sarwar, Usama, Raza, Abida
core +1 more source
Intratumoral Anti-PD1 Nanoformulation Improves Its Biodistribution
Intratumoral administration of immune checkpoint inhibitors, such as programmed cell death-1 antibodies (aPD-1), is a promising approach toward addressing both the low patients’ responses and high off-target toxicity, but good preclinical results have ...
Nicole Dmochowska (12329774) +9 more
core +2 more sources
Nematicidal Properties of Chitosan Nanoformulation
Abstract Chitosan is the second most abundant bio-polymer available in the world, second only to cellulose. It is found in crustaceous shells, e.g., those of crabs, shrimps, prawns, and fungi, as well as insect exoskeletons.
Mouniga R. +4 more
openaire +3 more sources
Nanoformulations as a modern form of biofungicide [PDF]
Abstract Purpose The aim of this study was to elaborate new forms of biofungicide formulations which could increase biological activity of essential oil against various strains of pathogenic fungi of plants, dermatophytes, and molds. Methods The nanoemulsions containing four various essential oils (cinnamon, thyme, manuka, and tea tree oil) were ...
Małgorzata Miastkowska +3 more
openaire +3 more sources
Surface morphology of optimized nanoformulation.
Surface morphology of optimized nanoformulation.
Mihir Raval (12542560) +5 more
core +1 more source

