Results 41 to 50 of about 12,080 (272)

Nanonutraceuticals: Anti-Cancer Activity and Improved Safety of Chemotherapy by Costunolide and Its Nanoformulation against Colon and Breast Cancer

Biomedicines, 2021
Costunolide (COS) is a sesquiterpene lactone with anticancer properties. The present study investigated the anticancer effects of COS against the human colon (HCT116) and breast (MDA-MB-231-Luc) cancer cell lines.
Ali H. El-Far, Kavitha Godugu, Taher A. Salaheldin, Noureldien H. E. Darwish, Amna A. Saddiq, Shaker A. Mousa   +5 more
doaj   +1 more source

Dihydroartemisinin-driven selective anti-lung cancer proliferation by binding to EGFR and inhibition of NRAS signaling pathway-induced DNA damage

Scientific Reports
Chemotherapeutic agents can inhibit the proliferation of malignant cells due to their cytotoxicity, which is limited by collateral damage. Dihydroartemisinin (DHA), has a selective anti-cancer effect, whose target and mechanism remain uncovered.
Liu-Gen Li, Xing-Chun Peng, Zi-Yi Yang, Ning Han, Chang-Long Gou, Jun Shi, Li-Li Yu, Nan-Nan Chen, Ting-Ting Yu, Tong-Fei Li, Xian-Yu Li, Jun Hu   +11 more
doaj   +1 more source

Endoplasmic reticulum-targeted Cepharanthine-loaded metal–organic framework nanoreactor potentiates immunotherapy for hepatocellular carcinoma

Materials & Design
Our previous work revealed that cepharanthine (Cep) could elicit endoplasmic reticulum (ER) stress for blocking hepatocellular carcinoma (HCC) development. Nevertheless, the limited distribution of Cep in the ER of HCC restricts its application.
Nan-Nan Chen, Ning Han, Chen-Yu Wang, Liu-Gen Li, Yufei Qin, Shao-Pu Luo, Zhuo Xiang, Fan Leng, Yuan-Jian Hui, Qi Huang, Jun Hu   +10 more
doaj   +1 more source

Nanocarriers in Tuberculosis Treatment: Challenges and Delivery Strategies

Pharmaceuticals, 2023
The World Health Organization identifies tuberculosis (TB), caused by Mycobacterium tuberculosis, as a leading infectious killer. Although conventional treatments for TB exist, they come with challenges such as a heavy pill regimen, prolonged treatment ...
Mahesh Kumar, Tarun Virmani, Girish Kumar, Rohitas Deshmukh, Ashwani Sharma, Sofia Duarte, Pedro Brandão, Pedro Fonte   +7 more
doaj   +1 more source

Blood–Brain Barrier Regulation: Evolving From Classic Strategies to Electrochemical Ion and Reactive Oxygen Species Control

Advanced Healthcare Materials, EarlyView.
Conventional therapies suffer from poor blood–brain barrier (BBB) penetration and disordered ion/reactive oxygen species (ROS) homeostasis, hindering precise neurological treatment. Electrochemical strategies achieve accurate spatiotemporal regulation of neural homeostasis.
Xiaokang Hu, Caiyu Liu, Meijun Pang, Zhiyuan Shi, Dong Ming, Xiuyun Liu   +5 more
wiley   +1 more source

Determining M2 macrophages content for the anti-tumor effects of metal-organic framework-encapsulated pazopanib nanoparticles in breast cancer

Journal of Nanobiotechnology
Pazopanib (PAZ), an oral multi-tyrosine kinase inhibitor, demonstrates promising cytostatic activities against various human cancers. However, its clinical utility is limited by substantial side effects and therapeutic resistance.
Zhijie Xu, Zhiyang Zhou, Xiaoxin Yang, Abhimanyu Thakur, Ning Han, Hai-Tao Li, Liu-Gen Li, Jun Hu, Tong-fei Li, Yuanliang Yan   +9 more
doaj   +1 more source

Silica-based Antibacterial and Antifungal Nanoformulation [PDF]

, 2012
A silica-based nanoformulation and method is used to treat citrus canker, inhibit the growth of mold and mildew, and add nutrients to soil used for agricultural purposes. The nanotechnology-enabled copper-loaded, silica nanoformulation (CuSiNP/NG) design
Santra, Swadeshmukul
core  

Polyphenol‐Inspired Materials for Agricultural Applications

Advanced Materials, EarlyView.
This review outlines the use of polyphenol‐inspired materials for sustainable agriculture, highlighting their molecular design, interfacial assembly, structure–property relationships, and prospects toward precision agriculture, climate resilience, ecosystem protection, and circular bioeconomy strategies.
Haofu Liu, Omid Mazaheri, Zhixing Lin, Tianzheng Wang, Jingqu Chen, Yuang Gu, Xia Liang, Deli Chen, Frank Caruso   +8 more
wiley   +1 more source

Silica-based Antibacterial and Antifungal Nanoformulation DIV [PDF]

, 2014
A silica-based nanoformulation and method is used to treat citrus canker, inhibit the growth of mold and mildew, and add nutrients to soil used for agricultural purposes. The nanotechnology-enabled copper-loaded, silica nanoformulation (CuSiNP/NG) design
Santra, Swadeshmukul
core  

Developments of Cyanobacteria for Nano-Marine Drugs: Relevance of Nanoformulations in Cancer Therapies

Marine Drugs, 2018
Current trends in the application of nanomaterials are emerging in the nano-biotechnological sector for development of medicines. Cyanobacteria (blue-green algae) are photosynthetic prokaryotes that have applications to human health and numerous ...
Vivek K. Bajpai, Shruti Shukla, Sung-Min Kang, Seung Kyu Hwang, Xinjie Song, Yun Suk Huh, Young-Kyu Han   +6 more
doaj   +1 more source