Results 51 to 60 of about 12,080 (272)

Availability of Metribuzin-Loaded Polymeric Nanoparticles in Different Soil Systems: An Important Study on the Development of Safe Nanoherbicides

Plants, 2022
Nanoformulations have been used to improve the delivery of fertilizers, pesticides, and growth regulators, with a focus on more sustainable agriculture.
Vanessa Takeshita, Gustavo Vinicios Munhoz-Garcia, Camila Werk Pinácio, Brian Cintra Cardoso, Daniel Nalin, Valdemar Luiz Tornisielo, Leonardo Fernandes Fraceto   +6 more
doaj   +1 more source

Design and Evaluation of pH-Sensitive Nanoformulation of Bergenin Isolated from Bergenia ciliata

, 2022
The aim of the current study is extraction and isolation of bergenin from Bergenia ciliata and fabrication of pH-sensitive Eudragit(®) L100 (EL100) polymeric nanoparticles (NP) to tackle limitations of solubility.
Naveed Ahmed, Bashir, Kashaf, Mirza, Bushra, Khan, Muhammad Farhan Ali, Fatima, Humaira, Iffat Naz, Humaira Fatima, Ahmed, Naveed, Kashaf Bashir, Aiyeshah Alhodaib, Muhammad Khalid Tipu, Muhammad Farhan Ali Khan, Bushra Mirza, Alhodaib, Aiyeshah, Naz, Iffat, Tipu, Muhammad Khalid   +15 more
core   +1 more source

Cerium Nanoparticle‐Mediated Inhibition of the NSUN2/m5C Axis Suppresses Synovial Aggression in Rheumatoid Arthritis

Advanced Science, EarlyView.
A novel epitranscriptomic mechanism in rheumatoid arthritis is uncovered: NSUN2 promotes disease via m5C‐dependent stabilization of ICMT mRNA, fueling the migration and invasion of pathogenic RA FLS. Targeting this axis with engineered nanoparticles (Ce/SAA NPs) effectively inhibits disease progression, presenting a precise therapeutic strategy ...
Ruiru Li, Simin Chen, Huijuan Hu, Shiyao Wu, Jingnan Wang, Kai Sun, Chenxi Peng, Suling Liu, Shuoyang Zhang, Yu Kuang, Wei Chen, Qian Qiu, Liuqin Liang, Yu Wen, Hanshi Xu, Youjun Xiao   +15 more
wiley   +1 more source

Combined Nanofibrous Face Mask: Co-Formulation of Lipases and Antibiotic Agent by Electrospinning Technique

Pharmaceutics, 2023
The application of enzyme-based therapies has received significant attention in modern drug development. Lipases are one of the most versatile enzymes that can be used as therapeutic agents in basic skin care and medical treatment related to excessive ...
Diána Balogh-Weiser, Alexandra Molnár, Gergő D. Tóth, Gábor Koplányi, József Szemes, Balázs Decsi, Gábor Katona, Maryana Salamah, Ferenc Ender, Anita Kovács, Szilvia Berkó, Mária Budai-Szűcs, György T. Balogh   +12 more
doaj   +1 more source

EphB1‐Mediated Transient Blood‐Brain Barrier Opening Facilitates a Ferritin‐Based Nanotherapeutic for Alzheimer's Disease

Advanced Science, EarlyView.
We constructed a brain‐targeted AFn‐DPZ nanodrug delivery system and identified EphB1 as its receptor on the blood‐brain barrier (BBB). This system facilitates drug transport across the BBB and thereby ameliorates cognitive impairment in Alzheimer's disease.
Shilin Wen, Jingjing Gao, Zhixian Wang, Qiumin Ma, Xiao‐Ling Xu, Jianer Chen   +5 more
wiley   +1 more source

A Review of the Anti-Inflammatory Skincare Potential of Epilobium angustifolium (Fireweed) Inspired by Herbal Tradition

Cosmetics
The demand for naturally derived cosmetic ingredients is rising as consumers increasingly prioritize green and environmentally friendly products. Naturally derived ingredients, such as plant extracts rich in polyphenols like flavonoids and tannins, are ...
Jaana Ailus, Imran Saleem, Fyaz M. D. Ismail   +2 more
doaj   +1 more source

Composite Nanoformulation Therapeutics for Long-Term Ocular Delivery of Macromolecules

, 2016
The purpose of this investigation is to design and synthesize novel pentablock (PB) copolymer (PB-1: PCL–PLA–PEG–PLA–PCL) based nanoformulations suspended in a thermosensitive gelling copolymer (PB-2: mPEG–PCL–PLA–PCL–PEGm) termed as composite ...
Vibhuti Agrahari (2349967), Lane K. Christenson (82709), Wei-Ting Hung (1938895), Vivek Agrahari (2349973), Ashim K. Mitra (2349970)   +4 more
core   +1 more source

Unraveling Bone‐Skin Crosstalk Enables miRNA Nanoformulation for Cutaneous Neurovascular Reconstruction in Diabetic Mice

Advanced Science, EarlyView.
This study unravels that bone fracture accelerates diabetic wound healing by releasing exosomal microRNA (miR‐130b‐3p). To mimic this bone‐skin crosstalk, we engineered a self‐assembling agomir‐130b‐3p nanocomplex. Delivered via a photocrosslinkable hydrogel, this bio‐inspired therapy provides sustained localized agomir release.
Tao Shen, Hongdou Shen, Weiyue Wu, Zhuoying Jiang, Bin Liu, Yansi Xian, Rui Peng, An Yan, Yu Ben, Yong Shi, Xiang Chen, Baosheng Guo, Qing Jiang, Weijun Wang, Pingqiang Cai   +14 more
wiley   +1 more source

A nanoformulation of cisplatin with arabinoxylan having enhanced activity against hepatocellular carcinoma through upregulation of apoptotic and necroptotic pathways

Heliyon
Cisplatin is a versatile drug used to treat various types of cancer, but it is associated with high toxicity and resistance problems. Several approaches, including nanotechnology, have been adopted to minimize the toxic effects and to overcome the ...
Sidra Rana, Sania Shahid, Mohammad Saeed Iqbal, Adnan Arshad, Dilawar Khan   +4 more
doaj   +1 more source

Targeted β‐Glucan‐Veiled Oral Apremilast Nanotherapy Modulates Key Dysbiosis‐Associated Gut Microbiota and Alleviates Ulcerative Colitis‐Associated Anxiety, Depression, and Neuropsychiatric Behaviors

Advanced Science, EarlyView.
This study introduces β‐glucan‐shielded apremilast laden nanomicelles that withstand gastrointestinal degradation, selectively accumulate in inflamed colon tissue, and modulate the microbiota–gut–brain axis. The formulation restores barrier integrity, reduces systemic and neuroinflammation, and improves anxiety‐ and depression‐like behaviors in colitis
Chandrashekhar Jori, Ahmed Shaney Rehman, Taruna Lamba, Anas Ahmad, Jattin Kumar, Aneesh Ali, Ajesh Joshi, Ashraf Ali, Suhel Parvez, Javed N. Agrewala, Rehan Khan   +10 more
wiley   +1 more source