Results 51 to 60 of about 105,790 (331)

Bionanomedicine: A “Panacea” In Medicine?

open access: yesMakara Journal of Health Research, 2017
Recent advances in nanotechnology, biotechnology, bioinformatics, and materials science have prompted novel developments in the field of nanomedicine. Enhancements in the theranostics, computational information, and management of diseases/disorders are ...
Dito Anurogo   +2 more
doaj   +1 more source

Mechano-boosting nanomedicine antitumour efficacy by blocking the reticuloendothelial system with stiff nanogels

open access: yesNature Communications, 2023
Nanomedicine proofed to be efficient in cancer therapy but rapid clearance from blood circulation by reticuloendothelial system (RES) severely limits the antitumor efficacy.
Zheng Li   +11 more
semanticscholar   +1 more source

Nanomedicine

open access: yesOpen Schools Journal for Open Science, 2020
Important and life-sustaining processes such as teh uptake, transport and metabolism of biologicla substances take place on cellular level in the human body. Diseases and disorders happening on this level can now be targeted with diagnostic and threapeutic tools in the nano-scaled size range.
Winkler, L.   +4 more
openaire   +3 more sources

Unleashing the Power of Machine Learning in Nanomedicine Formulation Development

open access: yesAdvanced Functional Materials, EarlyView.
A random forest machine learning model is able to make predictions on nanoparticle attributes of different nanomedicines (i.e. lipid nanoparticles, liposomes, or PLGA nanoparticles) based on microfluidic formulation parameters. Machine learning models are based on a database of nanoparticle formulations, and models are able to generate unique solutions
Thomas L. Moore   +7 more
wiley   +1 more source

Urea supplementation improves mRNA in vitro transcription by decreasing both shorter and longer RNA byproducts

open access: yesRNA Biology
The current letter to the editor describes the presence of RNA byproducts in small-scale in vitro transcription (IVT) reactions as evaluated by capillary gel electrophoresis, asymmetric flow field flow fractionation, immunoblotting, cell-free translation
Combes Francis   +6 more
doaj   +1 more source

Tailoring the Properties of Functional Materials With N‐Oxides

open access: yesAdvanced Functional Materials, EarlyView.
The properties of materials bearing N‐oxide groups are often dominated by the polar N+─O− bond. It provides hydrophilicity, selective ion‐binding, electric conductivity, or antifouling properties. Many of the underlying mechanisms have only recently been discovered, and the interest in N‐oxide materials is rapidly growing.
Timo Friedrich   +5 more
wiley   +1 more source

Supramolecular nanostructure mimics GDNF trophic effects in vitro on human dopaminergic neurons

open access: yesnpj Regenerative Medicine
Peptide-based supramolecular nanostructures offer a versatile platform with substantial promise for clinical translation in regenerative medicine.
Oscar A. Carballo-Molina   +12 more
doaj   +1 more source

Discovery of MBL-AB01: a novel antibacterial xanthone antibiotic with high activity against methicillin-resistant Staphylococcus aureus

open access: yesApplied and Environmental Microbiology
A novel compound denoted MBL-AB01 was isolated from a marine Actinoalloteichus, which belongs to a rare and underexplored class of Actinobacteria. This work demonstrates that the novel compound MBL-AB01 shows very high activity in vitro against six ...
Kristin Fløgstad Degnes   +14 more
doaj   +1 more source

AKT2 siRNA delivery with amphiphilic-based polymeric micelles show efficacy against cancer stem cells

open access: yesDrug Delivery, 2018
Development of RNA interference-based therapies with appropriate therapeutic window remains a challenge for advanced cancers. Because cancer stem cells (CSC) are responsible of sustaining the metastatic spread of the disease to distal organs and the ...
Diana Rafael   +12 more
doaj   +1 more source

Recent Advances in Nanomedicine for the Diagnosis and Therapy of Liver Fibrosis

open access: yesNanomaterials, 2020
Liver fibrosis, a reversible pathological process of inflammation and fiber deposition caused by chronic liver injury and can cause severe health complications, including liver failure, liver cirrhosis, and liver cancer.
Xue Bai, Gaoxing Su, Shumei Zhai
doaj   +1 more source

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