Results 61 to 70 of about 89,367 (293)
Direct RNA sequencing coupled with adaptive sampling enriches RNAs of interest in the transcriptome
Nature CommunicationsAbundant cellular transcripts occupy most of the sequencing reads in the transcriptome, making it challenging to assay for low-abundant transcripts. Here, we utilize the adaptive sampling function of Oxford Nanopore sequencing to selectively deplete and ...
Jiaxu Wang +7 more
doaj +1 more source
tRNA Modification Detection Using Graphene Nanopores: A Simulation Study
Biomolecules, 2017 There are over 100 enzyme-catalyzed modifications on transfer RNA (tRNA) molecules. The levels and identity of wobble uridine (U) modifications are affected by environmental conditions and diseased states, making wobble U detection a potential biomarker ...
Khadijah Onanuga +3 more
doaj +1 more source
Direct RNA Sequencing Unfolds the Complex Transcriptome of Vibrio parahaemolyticus
mSystems, 2021 Conventional bacterial genome annotation provides information about coding sequences but ignores untranslated regions and operons. However, untranslated regions contain important regulatory elements as well as targets for many regulatory factors, such as
Mohamad Al kadi +7 more
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Sequence dependence of DNA translocation through a nanopore [PDF]
, 2007 We investigate the dynamics of DNA translocation through a nanopore using 2D Langevin dynamics simulations, focusing on the dependence of the translocation dynamics on the details of DNA sequences.
Ala-Nissila, Tapio +3 more
core +2 more sources
Domain Wall Rebounds Driven by Competing Entropic and Spin‐Transfer Torques in Cylindrical Nanowires
Advanced Functional Materials, EarlyView.Domain‐wall motion in cylindrical magnetic nanowires driven by nanosecond current pulses. Low current densities efficiently displace domain walls, whereas higher currents cause rebound at the wire ends. The effect results from the interplay between spin‐transfer torque and thermally induced processes, highlighting the role of thermal gradients in ...
Elias Saugar +11 more
wiley +1 more source
Whole genome sequencing in animal health: applications, challenges, and future directions
BMC Veterinary ResearchWGS is revolutionizing animal health diagnostics, offering unprecedented opportunities for pathogen detection and biomarker identification, while offering increased depth of data, in comparison to more targeted approaches such as amplicon sequencing ...
Johannes Charlier +7 more
doaj +1 more source
Frontiers in Neuroscience, 2016 Artificial chemical stimulation could provide improvements over electrical neurostimulation. Physiological neurotransmission between neurons relies on the nanoscale release and propagation of specific chemical signals to spatially-localized receptors ...
Peter D Jones, Martin eStelzle
doaj +1 more source
mSystems, 2021 Alternative splicing is a widespread phenomenon in metazoans by which single genes are able to produce multiple isoforms of the gene product. However, this has been poorly characterized in apicomplexans, a major phylum of some of the most important ...
V. Vern Lee +5 more
doaj +1 more source
, 2009 In this paper we present a method for the real-time detection of the bases of the deoxyribonucleic acid using their signatures in negative differential conductance measurements.
Dragoman, Daniela, Dragoman, Mircea
core +1 more source
Advanced Functional Materials, EarlyView.We report a polymer‐chain insertion strategy to fabricate pore‐threaded MOF thin films with precisely tuned surface chemistry and wettability. Grafting n‐alkane chains into the pillared layer Cu2(bdc)2(dabco) MOF thin film's vertical nanochannels enhances water stability, and induces hydrophobicity and lubricant‐free, solid‐like slippery behavior ...
Angana Borbora +4 more
wiley +1 more source