Solid-state nanopore sensing reveals conformational changes induced by a mutation in a neuron-specific tRNAArg. [PDF]
Dutt S +8 more
europepmc +1 more source
Recent Advances in Chemical Probing Strategies for RNA Structure Determination in Vivo
This Review illustrates how structural probes combined with advanced sequencing technologies are revolutionizing our ability to map RNA structures and interactions within living cells. It highlights the development of innovative strategies tailored to probe RNA structures in particular biological contexts.
Maryana Yarshova +2 more
wiley +1 more source
Mini‐Hairpin DNA: Extraordinarily Stable Structure and Its Applications
Mini‐hairpin DNA fragments containing GCGAAGC and GCGAAAGC form exceptionally stable hairpin‐like structures, with only two G−C pairs and one sheared G−A pair, remaining undenatured in 7 M urea and resisting nuclease digestion. These mini‐hairpin sequences frequently appear in replication and transcription origins, influence DNA sequencing fidelity ...
Michiko Kimoto, Ichiro Hirao
wiley +1 more source
Nanopore-based sensing for biomarker detection: from fundamental principles to translational diagnostics. [PDF]
Shrikrishna NS, Gandhi S.
europepmc +1 more source
In Vivo Cytoskeletal AMPA Receptor Transport Imaging in C. elegans
ABSTRACT Long‐distance intracellular transport of ionotropic glutamate receptors (iGluRs) is essential for proper excitatory synaptic function underlying learning and memory. Many neuropsychiatric and neurodegenerative conditions have abnormal iGluR transport and trafficking, leading to an intense interest in the mechanisms and factors regulating these
Michaelis A. K., Hoerndli F. J.
wiley +1 more source
Aquaporin embedded suspended lipid bilayer on anodized alumina nanoporous substrates for studying stability and functionality: towards the development of a miniaturized water purifier. [PDF]
Kumari A +2 more
europepmc +1 more source
Recent advances in boosting interfacial bubble dynamics with external fields
External physical fields, including acoustic, magnetic, thermal, mechanical, and optical stimuli, accelerate the entire bubble‐dynamics sequence of nucleation, growth, and detachment. Abstract The efficiency of industrial electrocatalytic reactions depends not only on generating gaseous products but also on their detachment from the catalyst surface ...
Wenlu Xie +5 more
wiley +1 more source
Comparison among Amber-ff14SB, Amber-ff19SB, and CHARMM36 Force Fields for Ionic and Electroosmotic Flows in Biological Nanopores. [PDF]
Gargano S +4 more
europepmc +1 more source
Evolution of the water cluster in pore condensation
In pore condensation, lower contact angles reduce molecular displacement (60%) and potential energy (10%), enhancing vapor capture tenfold. Pores restrict water molecule mobility, promoting condensation. On hydrophobic surfaces (124∘$^\circ$), pores stabilize embryos, ensuring uniform condensation within pores, boosting nucleation efficiency.
Boxuan Cui +4 more
wiley +1 more source

