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Nanopore sequencing technology: nanopore preparations

Trends in Biotechnology, 2007
For the past decade, nanometer-scale pores have been developed as a powerful technique for sensing biological macromolecules. Various potential applications using these nanopores have been reported at the proof-of-principle stage, with the eventual aim of using them as an alternative to de novo DNA sequencing.
Minsoung, Rhee, Mark A, Burns
openaire   +2 more sources

The Nanopore Electrode

Analytical Chemistry, 2004
The fabrication and electrochemical characterization of truncated cone-shaped nanopore electrodes are reported. A nanopore electrode is a Pt disk electrode embedded at the bottom of a conical pore, the circular orifice of the pore having nanometer dimensions.
Bo, Zhang, Yanhui, Zhang, Henry S, White
openaire   +2 more sources

Nanopore Cheminformatics

DNA and Cell Biology, 2004
A cheminformatics method is described for classification, and biophysical examination, of individual molecules. A novel molecular detector is used--one based on current blockade measurements through a nanometer-scale ion channel (alpha-hemolysin). Classification results are described for blockades caused by DNA molecules in the alpha-hemolysin nanopore
Stephen, Winters-Hilt, Mark, Akeson
openaire   +2 more sources

DNA Translocation through Graphene Nanopores

open access: yesNano Letters, 2010
We report on DNA translocations through nanopores created in graphene membranes. Devices consist of 1-5 nm thick graphene membranes with electron-beam sculpted nanopores from 5 to 10 nm in diameter.
Ken Healy, Meni Wanunu, Vishva Ray
exaly   +2 more sources

Fluorescence biosensing in nanopores

2009 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, 2009
Hydrated nanopores offer a unique environment for studying biological molecules under controlled conditions and fabricating sensors using fluorescence. Silica nanopores for example are non-toxic, biologically and optically compatible with protein, and can be easily synthesized to entrap protein and exclude potentially interfering macromolecules, while ...
Karolin, Jan   +4 more
openaire   +4 more sources

Editorial: Nanopore Electrochemistry

Chemistry – An Asian Journal, 2023
This Special Collection highlights the most recent developments in nanopore electrochemistry and applications. In this Editorial, guest Editors Yi-Tao Long, Meni Wanunu, and Mathias Winterhalter briefly introduce the research published in this special collection.
Yi‐Tao Long   +2 more
openaire   +2 more sources

Characterization of Nanoporous Materials

Annual Review of Chemical and Biomolecular Engineering, 2021
Detailed analysis of textural properties, e.g., pore size and connectivity, of nanoporous materials is essential to identify correlations of these properties with the performance of gas storage, separation, and catalysis processes. The advances in developing nanoporous materials with uniform, tailor-made pore structures, including the introduction of ...
M, Thommes, C, Schlumberger
openaire   +2 more sources

A nanopore workhorse

Nature Methods, 2012
Voltage-driven and enzyme-regulated control allows precise ratcheting of a DNA strand in and out of a nanopore.
openaire   +2 more sources

Adsorbate Transport in Nanopores

Adsorption, 2005
We present a tractable theory of transport of simple fluids in cylindrical nanopores, considering trajectories of molecules between diffuse wall collisions at low-density, and including viscous flow contributions at higher densities. The model is validated through molecular dynamics simulations of supercritical methane transport, over a wide range of ...
Bhatia, SK, Jepps, OG, Nicholson, D
openaire   +3 more sources

Protein conducting nanopores

Journal of Physics: Condensed Matter, 2010
About 50% of the cellular proteins have to be transported into or across cellular membranes. This transport is an essential step in the protein biosynthesis. In eukaryotic cells secretory proteins are transported into the endoplasmic reticulum before they are transported in vesicles to the plasma membrane.
Harsman, Anke   +7 more
openaire   +3 more sources

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