Results 31 to 40 of about 47,549 (275)

Membrane-Suspended Nanopores in Microchip Arrays for Stochastic Transport Recording and Sensing

Frontiers in Nanotechnology, 2021
The transport of nutrients, xenobiotics, and signaling molecules across biological membranes is essential for life. As gatekeepers of cells, membrane proteins and nanopores are key targets in pharmaceutical research and industry. Multiple techniques help
Tim Diederichs, Robert Tampé
doaj   +1 more source

New theory of femtosecond induced changes and nanopore formation [PDF]

, 2011
Recent results confirm the presence of molecular oxygen proving that recombination of dissociated silica bonds does not occur. This combined with the observation of nanopores within the nanograting structure in silica, leads to a new interpretation of ...
Canning, John, Cook, Kevin, Lancry, Matthieu, Poumellec, Bertrand   +3 more
core   +1 more source

Nanopore Fabrication by Controlled Dielectric Breakdown

, 2013
Nanofabrication techniques for achieving dimensional control at the nanometer scale are generally equipment-intensive and time-consuming. The use of energetic beams of electrons or ions has placed the fabrication of nanopores in thin solid-state ...
Briggs, Kyle, Kwok, Harold, Tabard-Cossa, Vincent   +2 more
core   +3 more sources

Reversible positioning of single molecules inside zero-mode waveguides [PDF]

, 2014
We have developed a hybrid nanopore/zero-mode waveguide device for single-molecule fluorescence and DNA sequencing applications. The device is a freestanding solid-state membrane with sub-5 nm nanopores that reversibly delivers individual biomolecules to
Foquet, Mathieu, Korlach, Jonas, Larkin, Joseph, Turner, Stephen W., Wanunu, Meni   +4 more
core   +2 more sources

Fabrication and application of double-layer nanopore

Jin'gangshi yu moliao moju gongcheng
Solid-state nanopores have become the most promising single-molecule sequencing tools due to their adjustable pore size, stable physical and chemical properties, strong adaptability to extreme environments, and high integration.
Jieyu HUANG, Zhaowei ZENG, Chengyong WANG, Zhishan YUAN   +3 more
doaj   +1 more source

ELECTRICAL NOISES REDUCTION IN NANOPORES EXPERIMENTS BASED ON CONSENSUS FILTER [PDF]

Química Nova
Nanopore has developed into an indispensable tool for single molecules experiments, where useful information about the characteristics of DNA/RNA can be obtained from the flowing of ionic current elicited by individual molecules as they traverse a single
Bingyong Yan, Haixu Cui, Jiale Zhou, Huifeng Wang   +3 more
doaj   +2 more sources

Photocatalytic properties of TiO2 nanostructures of different morphology modified with various modifiers; pp. 168-177 [PDF]

Proceedings of the Estonian Academy of Sciences, 2019
Synthesis of TiO2 nanotube coatings, nanoporous coatings, and nanofibres by using titanium anodizing, microplasma electrolytic oxidation, and microwave-assisted hydrothermal synthesis in different regimes was studied.
Reinis Drunka, Janis Grabis, Dzidra Jankovica, Dzintra-Arija Rasmane, Aija Krumina   +4 more
doaj   +1 more source

Aerolysin Nanopores for Single-Molecule Analysis

CHIMIA
Biological nanopores have become powerful tools for single-molecule analysis in many fields, including metal ion detection, single-molecule chemistry, polymer size discrimination, nucleic acid sequencing, and protein/peptide/glycan analysis.
Yun Zhang, Chan Cao
doaj   +1 more source

Complementarity of Long‐Reads and Optical Mapping in Parkinson's Disease for Structural Variants

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Long‐read sequencing and optical genome mapping technologies have the ability to detect large and complex structural variants. This has led to the discovery of novel pathogenic variants in neurodegenerative movement disorders. Thus, we aimed to systematically compare the SV detection capabilities of OGM and ONT in Parkinson's disease.
André Fienemann, Theresa Lüth, Susen Schaake, Carolin Gabbert, Marius Möller, Hauke Busch, Katja Lohmann, Jonas A. Gustafson, Danny E. Miller, Kensuke Daida, Manabu Funayama, Nobutaka Hattori, Samia Ben Sassi, Faycel Hentati, Matthew J. Farrer, Kristian K. Ullrich, Christine Klein, Joanne Trinh   +17 more
wiley   +1 more source

Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz, Christopher H. Thompson, Linda C. Laux, Alfred L. George Jr.   +3 more
wiley   +1 more source