Results 41 to 50 of about 1,186,849 (283)

Hypolipidemic Activity of Olive Oil-Based Nanostructured Lipid Carrier Containing Atorvastatin

Nanomaterials, 2022
Currently, hyperlipidemia is a growing health issue that is considered a risk factor for obesity. Controlling body weight and modifying life style in most of cases are not adequate and the condition requires medical treatment.
Heba S. Elsewedy, Tamer M. Shehata, Mervt M. Almostafa, Wafaa E. Soliman   +3 more
doaj   +1 more source

Solid Lipid Nanoparticles: A Potential Approach for Dermal Drug Delivery [PDF]

, 2014
Solid lipid nanoparticles (SLNs) have attracted increasing attention during recent years. Due to their unique size dependent properties, lipid nanoparticles offer possibilities to develop new therapeutics.
Conway, Barbara R, Kakadia, Pratibha G., Kakadia, Partibha, Conway, Barbara; id_orcid   +3 more
core   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Fluorination: A strategy to tune the interactions of molecules and nanoscale systems with biological matter

FEBS Open Bio, EarlyView.
This minireview explores fluorination as a key strategy to optimize therapeutic molecules and nanocarriers. By incorporating different fluorinated motifs—from single atoms to linear and branched chains—drug delivery, cellular uptake, and colloidal stability can be improved and fine‐tuned.
Martina Beccalli, Beatrice Lucia Bona, Francesca Baldelli Bombelli   +2 more
wiley   +1 more source

Bioactive-fat engineered nanostructured lipid carriers from Illipe butter: optimized design and enhanced in vitro anti-inflammatory performance

Scientific Reports
Despite the extensive use of synthetic and semi-synthetic lipids in nanostructured lipid carrier (NLC) systems, the utilization of Shorea spp. (Illipe butter or tengkawang fat), an indigenous natural solid lipid from Indonesia, remains unexplored.
Insan Sunan Kurniawansyah, Anis Yohana Chaerunisaa, Nabila Nayif Nur Akmalia   +2 more
doaj   +1 more source

Nanostructured lipid carriers for MicroRNA delivery in tumor gene therapy

Cancer Cell International, 2018
MicroRNAs (miRNAs), which are endogenous about 20–23 nucleotides non-coding RNAs, have been acted as post-transcriptional regulators of gene expression.
Hairong Wang, Shiming Liu, Li Jia, Fengyun Chu, Ya Zhou, Zhixu He, Mengmeng Guo, Chao Chen, Lin Xu   +8 more
doaj   +1 more source

Programming Nanoscale Reaction Environments via Peptide Localization for Gold Nanoparticle Growth in Liposomal Nanoreactors

Advanced Functional Materials, EarlyView.
The liposome nanoreactor method enables uniform metal nanoparticle synthesis using the interior as a reaction environment. We demonstrate that peptide sequences and lipid compositions act as a functional molecular switch to control reaction environments in liposome nanoreactors.
Yuya Abe, Joseph Fox, Zabeada Aslam, Kevin Critchley, Stephen D. Evans, Mina Okochi, Masayoshi Tanaka   +6 more
wiley   +1 more source

Mammary gland tumor size in rats after treatment with nanostructured lipid carrier, tamoxifen-loaded nanostructured lipid carrier and tamoxifen-loaded erythropoietin-coated nanostructured lipid carrier.

, 2019
EPO-AMNLC and TAMNLC had significantly inhibited growth of rat mammary gland in time–dependent manner. NLC = Nanostructured lipid carrier; EPO–TAMNLC = Tamoxifen–loaded erythropoietin–coated NLC and TAMNLC = Tamoxifen–loaded NLC.
Abdul Rahman Omar (461449), Chee Wun How (6940808), Jhi Biau Foo (750442), Abdullah Rasedee (6940799), Latifah Saiful Yazan (565188), Chaw Yee Beh (6940796), Gayathri Thevi Selvarajah (6940802), Jia Ning Foong (6940805)   +7 more
core   +1 more source

Guanosine‐Quadruplex Hydrogels as Dynamic, Mechanically Tunable and Ion Conductive 3D Scaffolds for Cell Culture Applications

Advanced Functional Materials, EarlyView.
Versatile guanosine‐quadruplex (GQ) hydrogels are developed as dynamic biomatrices for cell culture. These scaffolds are fabricated under mild aqueous conditions, present improved stability, tunable mechanical properties within physiological ranges; fibrillar, porous microstructure, ion conductivity, and cytocompatibility.
Neha Thakur, Minye Jin, Pavel Milkin, Deepa Negi, Carla Cofiño Fabres, Hubert Gojzewski, Leonid Ionov, Alla Synytska, Andries van der Meer, Robert Passier, Julieta I. Paez   +10 more
wiley   +1 more source

Pengaruh Panjang Rantai Karbon Lipid Padat terhadap Karakteristik Nanostructured Lipid Carrier Resveratrol

JPSCR: Journal of Pharmaceutical Science and Clinical Research, 2019
Karakteristik kritis nano-structured lipid carrier (NLC) sangat dipengaruhi oleh komponen lipid padat dan lipid cair dalam sistem. Penelitian ini bertujuan untuk mengkaji pengaruh panjang rantai karbon dalam lipid padat terhadap karakteristik NLC ...
Siti Aisiyah, Reslely Harjanti, Vivin Nopiyanti   +2 more
doaj   +1 more source