Results 91 to 100 of about 4,359 (258)

Oxygen Vacancy‐Enriched Platinum Single‐Atom Nanozyme Wrapped in Nanoislands: Unlocking Catalytic Activity and Reprogramming Redox Microenvironment for Osteonecrosis Repair

open access: yesAdvanced Science, EarlyView.
CeO2‐x/Pt single‐atom nano‐island is constructed via low‐temperature reduction, featuring abundant oxygen vacancies and an island–sea structure. It delivers outstanding multi‐enzyme‐mimetic activity and ROS‐scavenging efficiency. Density functional theory reveals optimized electronic structures and reaction pathways.
Yang Zhu   +12 more
wiley   +1 more source

Pathological Mechanism‐Inspired Biomimetic Nano‐Senotherapy for Reversing Experimental Atherosclerosis in ApoE−/− Mice

open access: yesAdvanced Science, EarlyView.
The biomimetic self‐assembly nanomedicine reversing atherosclerosis via senotherapy strategy. ABSTRACT The greatest challenge in atherosclerosis (AS) management lies in achieving lesion reversal, not merely slowing progression. Senescent cell accumulation—driven by continuous generation and apoptotic resistance—perpetuates plaque pathology and ...
Yuhan Tian   +9 more
wiley   +1 more source

Development and Characterization of Bromocriptine Mesylate Loaded Nanostructured Lipid Carriers for Enhanced Nose-to-Brain Delivery

open access: yesPrecision Nanomedicine
Bromocriptine Mesylate is an alkaloid ergot derivative that acts as a dopamine D2 agonist. The work aims to develop nanostructured lipid carriers (NLCs) of bromocriptine mesylate to improve its bioavailability, which is only 28% orally. The nasal route
Darshan KA   +4 more
doaj   +1 more source

Nanostructured Lipid Carriers System Solid Lipid Poloxamer and Stearic Acid with Liquid Lipid Soybean Oil

open access: yesJurnal Ilmiah Medicamento, 2022
Nanostructured Lipid Carriers (NLC) are lipid-based carrier system that use a matrix combination in the form of solid and liquid which are stabilized with the addition of surfactant.
M Fatchur Rochman   +2 more
doaj  

Digestion stability of curcumin-loaded nanostructured lipid carrier

open access: gold, 2022
Ji Eun Hyun   +3 more
openalex   +1 more source

A Comprehensive Review on Nanostructured Lipid Carriers

open access: yesJournal of Drug Delivery and Therapeutics
Nanostructured lipid carriers (NLCs) mark a pivotal evolution in lipid-based drug delivery, surpassing the constraints of solid lipid nanoparticles (SLNs) to optimize therapeutic performance. Formulated with a mix of solid and liquid lipids, NLCs disrupt the rigid crystalline structure of SLNs, facilitating enhanced drug encapsulation, greater ...
R Prema   +3 more
openaire   +1 more source

All‐Flex Plasma Patch for In Vivo Delivery of Reactive Species

open access: yesAdvanced Science, EarlyView.
A fully flexible plasma patch enables stable, conformal treatment on complex biological surfaces and enhances transdermal delivery of reactive species. This platform achieves significant tumor suppression in vivo and reveals coordinated regulation of calcium signaling, metabolism, and programmed cell death, providing a promising strategy for safe and ...
Luxiang Zhao   +8 more
wiley   +1 more source

Advances in BODIPY Derivatives for Antibacterial Phototherapy

open access: yesAngewandte Chemie, EarlyView.
This review systematically summarizes the design strategies and structure‐activity relationships of BODIPY‐based antibacterial phototherapy, covering molecular engineering of small‐molecule photosensitizers and nanoplatforms, bacterial targeting and carrier design, and discussing the challenges and future perspectives associated with clinical ...
Li Lv   +9 more
wiley   +2 more sources

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