Results 71 to 80 of about 1,198,510 (287)
Lipid-based nanoparticles: innovations in ocular drug delivery
Frontiers in Molecular BiosciencesOcular drug delivery presents significant challenges due to intricate anatomy and the various barriers (corneal, tear, conjunctival, blood-aqueous, blood-retinal, and degradative enzymes) within the eye.
Mirza Salman Baig +12 more
doaj +1 more source
β-Carotene-loaded nanostructured lipid carriers produced by solvent displacement method
, 2020 Tristearin solid lipid nanoparticles and tristearin/high oleic sunflower oil nanostructured lipid carriers were produced by solvent displacement method.
Cunha, Rosiane Lopes +4 more
core +1 more source
A Cascaded DNA Nanocircuit for Multi‐Signal‐Responsive Precision siRNA Delivery in Cancer Therapy
Advanced Science, EarlyView.A cascaded dual‐AND logic DNA nanocircuit is engineered to respond to three tumor‐specific signals in a sequential manner: extracellular acidic pH, membrane‐overexpressed nucleolin (NCL), and intracellular glutathione (GSH). This programmable system selectively releases siPARP1 in glioblastoma (GBM), effectively silencing PARP1 and reversing TMZ ...
Yan Zhao +14 more
wiley +1 more source
Nanostructured Lipid Carriers in Pulmonary Drug Delivery: Progress and Prospects [PDF]
The potential of nanostructured lipid carriers to improve drug solubility, stability, and controlled release has made them a viable approach for pulmonary drug administration.
Manisha Dev, Pallavi Chandel
core +1 more source
Potential of Nanoparticle‐Based Phototherapies for Future Treatment of Uveal Melanoma
Advanced Science, EarlyView.This review evaluates nanoparticle‐based phototherapies for uveal melanoma, highlighting emerging strategies to enhance tumor targeting, light delivery, and treatment precision. Preclinical data indicate improved efficacy and reduced toxicity, supporting their potential to enhance localized treatment and future translational advances. (Generated by the
Emilie Lambert +8 more
wiley +1 more source
Pharmaceutical particulate carriers: Lipid - based carriers
National Journal of Physiology, Pharmacy and Pharmacology, 2012 Drug delivery research areas is continuously broaden and modified as a results of the realization of many factors (such as poor drug solubility and/or absorption, rapid metabolism, high fluctuation in the drug plasma level and variability) which play ...
Mohammed M. Mehanna +2 more
doaj +1 more source
Antitumoral melatonin-loaded nanostructured lipid carriers
NanomedicineAim: Cancer constitutes the second leading cause of death worldwide, with conventional therapies limited by significant side effects. Melatonin (MEL), a natural compound with antitumoral properties, suffers from instability and low solubility. To overcome these issues, MEL was encapsulated into nanostructured lipid carriers (MEL-NLC) containing rosehip
Lorena Bonilla-Vidal +7 more
openaire +4 more sources
, 2014 Yiqun Han,1,† Ying Zhang,2,† Danni Li,3 Yuanyuan Chen,1 Jiping Sun,1 Fansheng Kong4 1Department of Respiratory Medicine, General Hospital of Ji’nan Command, PLA, 2Center of Interventional Therapy, Ji’nan Infectious Disease ...
Li D +5 more
core
Advanced Science, EarlyView.This study reveals the long‐elusive intracellular dissolution mechanism of carrier‐free nanomedicines. By utilizing peak‐shifted dual‐state emissive FRET nanoprobes (PDFNPs) that undergo a distinct ratiometric fluorescence peak shift upon disassembly, we achieve real‐time, quantitative tracking of dissolution kinetics in live cells.
Farsai Taemaitree +18 more
wiley +1 more source
International Journal of Nanomedicine, 2012 Min Fang, Yilin Jin, Wei Bao, Hui Gao, Mengjin Xu, Di Wang, Xia Wang, Ping Yao, Liegang LiuDepartment of Nutrition and Food Hygiene, Hubei Key Laboratory of Food Nutrition and Safety, and Ministry of Education Key Laboratory of Environment and Health ...
Fang M +8 more
doaj