Results 181 to 190 of about 8,969 (258)

Nano-Engineered Cargo for Optimizing Oral Absorption of Tizanidine Nanostructured Lipid Carriers. [PDF]

open access: yesAdv Pharm Bull
Bazuhair MA   +9 more
europepmc   +1 more source

Cancer Vaccine Development: Toward Artificial Intelligence‐Assisted Personalized Cell Membrane Nanovaccine

open access: yesSmall, EarlyView.
Cancer nanovaccines have emerged as promising alternatives to conventional cancer vaccines, which have shown limited clinical efficacy. In particular, cell membrane nanoparticle‐based nanovaccines can offer high biocompatibility and immunogenicity while preserving tumor antigens, including antigen repertoires.
Munsik Kim, Ilkoo Noh
wiley   +1 more source

Reverse‐Engineered Lipid Nanoparticles Harness Protein Corona Formation for Cytokine Sequestration and Combination Immunomodulatory Therapy

open access: yesSmall, EarlyView.
Bioinspired triglyceride‐ceramide lipid nanoparticles were reverse‐engineered from cytokine‐sequestering plant‐derived nanoparticles to capture pathological inflammatory mediators through protein corona formation. Dexamethasone‐loaded TCNPs combine extracellular cytokine sequestration with intracellular immunomodulation, reducing IL‐6, TNF‐α, and NF‐κΒ
Junsik J. Sung   +2 more
wiley   +1 more source

Impact of Positively Charged Backbone Modifications on the Properties of Spherical Nucleic Acids

open access: yesSmall, EarlyView.
A synthesis of spherical nucleic acids (SNAs) featuring cationic backbone modifications is presented, together with an analysis of their emerging properties. Introducing positively charged guanidinium groups near the SNA surface enhances cellular uptake and offers a pathway toward more precise control over SNA internalization.
Katherine E. Bujold   +4 more
wiley   +1 more source

How We Simulate Nanopores

open access: yesSmall Methods, EarlyView.
Nanopore technology has revolutionized single‐molecule sensing, yet it suffers from an inherent interpretive challenge. Molecular dynamics has emerged as a go‐to method for determining the relationship between the structure of translocating molecules and the nanopore current signals.
Behzad Mehrafrooz   +5 more
wiley   +1 more source

Nanomaterials‐Decorated Biomass‐Derived Carbon for Overall Water Splitting: Interfacial Engineering, Mechanistic Insights, and Device Translation

open access: yesThe Chemical Record, EarlyView.
Biomass‐derived carbon provides a sustainable, porous, and conductive scaffold that stabilizes nanomaterials for bifunctional hydrogen evolution reaction/oxygen evolution reaction catalysis. This review summarizes design strategies (defects, heteroatom doping, heterostructures, single atoms), mechanistic/density functional theory insights, degradation ...
Paricha Jebin   +8 more
wiley   +1 more source

Engineering Nanoscale Frontiers: Valve Metal Oxide Nanostructures From Fundamentals to Multifunctional Biomedical Applications

open access: yesThe Chemical Record, EarlyView.
Valve metal oxide nanostructures such as TiO2, Ta2O5, Nb2O5, ZrO2, and HfO2 are emerging as versatile biomedical platforms due to their tunable surface properties, exceptional stability, and inherent biocompatibility. This review highlights their synthesis, physicochemical properties, and biological interactions, addressing their roles in advanced ...
Nina Kummer   +11 more
wiley   +1 more source

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