Results 181 to 190 of about 4,453 (214)
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2006
A more reliable laser diffractometer analytical procedure was developed to assess with higher accuracy the size of nanocrystals, the prerequisite for a sound formulation development. The screening procedure for optimised nanosuspension formulations was distinctly improved and the mechanism, leading to artefacts in the previous procedures, could be ...
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A more reliable laser diffractometer analytical procedure was developed to assess with higher accuracy the size of nanocrystals, the prerequisite for a sound formulation development. The screening procedure for optimised nanosuspension formulations was distinctly improved and the mechanism, leading to artefacts in the previous procedures, could be ...
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Recent Survey on Nanosuspension: A Patent Overview
Recent Patents on Drug Delivery & Formulation, 2015The major goals of designing nanosuspension of nanosize materials are increasing due to their tremendous potential as a drug delivery system with the wide range of applications. Nanosuspension is a unique tool for improving the bioavailability of poorly soluble drugs.
Sahilhusen I, Jethara +4 more
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Amorphous isradipine nanosuspension by the sonoprecipitation method
International Journal of Pharmaceutics, 2014The aims of this study are to increase and explain the mechanism of dissolution enhancement of isradipine using the sonoprecipitation method for stable nanosuspensions. There have been still few of published researches on formulation of isradipine using nanoparticle engineering.
Thao Truong-Dinh, Tran +6 more
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Preparation and cytotoxic activity of hydroxycamptothecin nanosuspensions
International Journal of Pharmaceutics, 2010Hydroxycamptothecin is a promising anticancer agent that possesses the ability to inhibit the growth of a wide range of human tumors. Owing to its poor solubility and instability, the pharmaceutical development and clinical utilization of hydroxycamptothecin have been limited.
Yong-Xing, Zhao +5 more
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Formulation and drying of miconazole and itraconazole nanosuspensions
International Journal of Pharmaceutics, 2013Miconazole and itraconazole possess adequate membrane permeability, but only slight water solubility, which limits their bioavailability and antifungal effect. To increase their dissolution rate, the compounds were nanoground by media milling to produce nanosuspensions with mean particle size of approximately 210 nm and stabilized with sodium ...
Ana M, Cerdeira +2 more
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Optical beam instabilities in nonlinear nanosuspensions
Optics Letters, 2007We investigate the modulation instability of plane waves and the transverse instabilities of soliton stripe beams propagating in nonlinear nanosuspensions. We show that in these systems the process of modulational instability depends on the input beam conditions.
El-Ganainy, R. +4 more
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Colloids and Surfaces B: Biointerfaces, 2016
The exploration of a simple and robust approach to produce nanosuspensions is a meaningful attempt for clinical translation. CO2-assisted effervescence was firstly developed to prepare nanosuspensions and was found to be easy for scale-up. Drug nanosuspensions were easily obtained by adding aqueous carbonate to the pre-treated mixture of drug ...
Xiangfei, Han +4 more
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The exploration of a simple and robust approach to produce nanosuspensions is a meaningful attempt for clinical translation. CO2-assisted effervescence was firstly developed to prepare nanosuspensions and was found to be easy for scale-up. Drug nanosuspensions were easily obtained by adding aqueous carbonate to the pre-treated mixture of drug ...
Xiangfei, Han +4 more
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Mechanism of freeze-drying drug nanosuspensions
International Journal of Pharmaceutics, 2012Drug nanoparticles prepared in a liquid medium are commonly freeze-dried for the preparation of an oral dosage in solid dosage form. The freezing rate is known to be a critical parameter for redispersible nanoformulations. However, there has been controversy as to whether a fast or slow freezing rate prevents irreversible aggregation.
Nae-Oh, Chung +2 more
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Plasmonic Resonant Solitons in Metallic Nanosuspensions
Nano Letters, 2014Robust propagation of self-trapped light over distances exceeding 25 diffraction lengths has been demonstrated for the first time in plasmonic nanosuspensions. This phenomenon results from the interplay between optical forces and enhanced polarizability that would have been otherwise impossible in conventional dielectric dispersions.
Shima, Fardad +5 more
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Nevirapine nanosuspensions for HIV reservoir targeting
Die Pharmazie, 2011In this paper we discuss, production, characterization and in-vivo evaluation of nevirapine nanosuspensions. Laser diffraction showed that the average particles size was 457 nm. Following single-dose administration, the plasma gamma concentration profiles showed fast release.
Singh, K. K., Shegokar, R.
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