Results 191 to 200 of about 7,736 (212)
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Preserving hesperetin nanosuspensions for dermal application.
Die Pharmazie, 2010Nanosuspensions as aqueous formulations need to be preserved. However, preservatives could vitiate the physical stability of suspensions and to a greater extent nanosuspensions. The impact of six varied preservatives on the physical stability of previously prepared nanosuspensions was studied.
Al Shaal, L. +2 more
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Preparation and Solidification of Redispersible Nanosuspensions
Journal of Pharmaceutical Sciences, 2014To test the feasibility of preparing redispersible powders from nanosuspensions without further addition of drying protectants, Lovastatin was processed into nanosuspensions and subsequently converted into a powder form using a spray-drying process.
Xin, Zhang +4 more
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Plasmonic Resonant Solitons in Metallic Nanosuspensions
Nano Letters, 2014Robust propagation of self-trapped light over distances exceeding 25 diffraction lengths has been demonstrated for the first time in plasmonic nanosuspensions. This phenomenon results from the interplay between optical forces and enhanced polarizability that would have been otherwise impossible in conventional dielectric dispersions.
Shima, Fardad +5 more
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Nevirapine nanosuspensions for HIV reservoir targeting.
Die Pharmazie, 2011In this paper we discuss, production, characterization and in-vivo evaluation of nevirapine nanosuspensions. Laser diffraction showed that the average particles size was 457 nm. Following single-dose administration, the plasma gamma concentration profiles showed fast release.
Singh, K. K., Shegokar, R.
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Colloids and Surfaces B: Biointerfaces, 2016
The exploration of a simple and robust approach to produce nanosuspensions is a meaningful attempt for clinical translation. CO2-assisted effervescence was firstly developed to prepare nanosuspensions and was found to be easy for scale-up. Drug nanosuspensions were easily obtained by adding aqueous carbonate to the pre-treated mixture of drug ...
Xiangfei, Han +4 more
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The exploration of a simple and robust approach to produce nanosuspensions is a meaningful attempt for clinical translation. CO2-assisted effervescence was firstly developed to prepare nanosuspensions and was found to be easy for scale-up. Drug nanosuspensions were easily obtained by adding aqueous carbonate to the pre-treated mixture of drug ...
Xiangfei, Han +4 more
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Safety of nanosuspensions in drug delivery
Nanomedicine: Nanotechnology, Biology and Medicine, 2017Nanosuspension technology is currently undergoing dramatic expansion in pharmaceutical science research and development. However, most of the research efforts generally focus on formulation and potential beneficial description, while the research into potential toxicological effects and implications (i.e., in vivo safety and health effects) is lacking.
Lulu Wang +3 more
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Amorphous isradipine nanosuspension by the sonoprecipitation method
International Journal of Pharmaceutics, 2014The aims of this study are to increase and explain the mechanism of dissolution enhancement of isradipine using the sonoprecipitation method for stable nanosuspensions. There have been still few of published researches on formulation of isradipine using nanoparticle engineering.
Thao Truong-Dinh, Tran +6 more
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Preparation and cytotoxic activity of hydroxycamptothecin nanosuspensions
International Journal of Pharmaceutics, 2010Hydroxycamptothecin is a promising anticancer agent that possesses the ability to inhibit the growth of a wide range of human tumors. Owing to its poor solubility and instability, the pharmaceutical development and clinical utilization of hydroxycamptothecin have been limited.
Yong-Xing, Zhao +5 more
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2014
Thesis (Masters by research(Mechanical and Manufacturing Engineering))--University of South Australia, 2014. Includes bibliographical references (pages 56-70) Poor aqueous solubility of some drug molecules is one of the major problems in drug formulations, resulting in many new drugs being withdrawn during the developmental stage due to their poor ...
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Thesis (Masters by research(Mechanical and Manufacturing Engineering))--University of South Australia, 2014. Includes bibliographical references (pages 56-70) Poor aqueous solubility of some drug molecules is one of the major problems in drug formulations, resulting in many new drugs being withdrawn during the developmental stage due to their poor ...
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Nanosuspensions: Enhancing drug bioavailability through nanonization
Annales Pharmaceutiques FrançaisesNanosuspensions have emerged as a promising avenue in pharmaceutical innovation, particularly for enhancing the bioavailability of poorly soluble medications. This article explores the transformative potential of nanosuspensions, emphasizing the critical role of particle size reduction through nanonization techniques. With conventional approaches often
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