Nanosuspension: An approach to enhance solubility of drugs
Journal of Advanced Pharmaceutical Technology & Research, 2011 One of the major problems associated with poorly soluble drugs is very low bioavailability. The problem is even more complex for drugs like itraconazole, simvastatin, and carbamazepine which are poorly soluble in both aqueous and nonaqueous media ...
Vishal R Patel, Y K Agrawal
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Study of colloidal behaviour and rheology of Al2O3-TiO2 nanosuspensions to obtain free-flowing spray-dried granules for atmospheric plasma spraying [PDF]
, 2013 This work deals with the dispersion and stabilisation of nanosized Al2O3 and TiO2 particles in aqueous medium. The dispersing conditions were studied as a function of pH, dispersant content, solid loading and ageing.
Mallol Gasch, Gustavo +3 more
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Recent advances in the engineering of nanosized active pharmaceutical ingredients: Promises and challenges [PDF]
, 2016 The advances in the field of nanotechnology have revolutionized the field of delivery of poorly soluble active pharmaceutical ingredients (APIs). Nanosized formulations have been extensively investigated to achieve a rapid dissolution and therefore ...
Al Shafiee, Maen, Kaialy, Waseem
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Nanosuspensions: a promising drug delivery strategy [PDF]
Journal of Pharmacy and Pharmacology, 2004 Abstract Nanosuspensions have emerged as a promising strategy for the efficient delivery of hydrophobic drugs because of their versatile features and unique advantages. Techniques such as media milling and high-pressure homogenization have been used commercially for producing nanosuspensions.
V B, Patravale +2 more
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Antibacterial activity of guava (Psidium guajava L.) leaf ethanolic extract nanosuspension against Escherichia coli bacteria [PDF]
PharmacianaDiarrhea is a condition where a person has bowel movements three or more times a day, with consistent stools. One of the common bacteria that causes diarrhea is Escherichia coli.
Lusi Nurdianti +5 more
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Frontiers in Chemistry, 2023 Cinnamomum zeylanicum is a traditional medicinal plant known for its anti-inflammatory, antidiabetic, antimicrobial, anticancer, and antioxidant properties. Its therapeutic efficacy using nanosuspensions is still unclear for treating infectious diseases.
Aqsa Nawaz +5 more
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Future Journal of Pharmaceutical Sciences, 2018 The present study deals with preparation of nanoformulations of epigallocatchin gallate (EGCG) alone and with piperine, and evaluation of in vivo cognitive effect on Swiss albino male mice.
Shakti Dahiya +4 more
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Smart nanocrystals of artemether: fabrication, characterization, and comparative in vitro and in vivo antimalarial evaluation [PDF]
, 2016 YesArtemether (ARTM) is a very effective antimalarial drug with poor solubility and consequently low bioavailability. Smart nanocrystals of ARTM with particle size of 161±1.5 nm and polydispersity index of 0.172±0.01 were produced in
AbdEl-Salam, N.M. +9 more
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Formulation and characterization of biocompatible and stable I.V. itraconazole nanosuspensions stabilized by a new stabilizer polyethylene glycol-poly(β-Benzyl-L-aspartate) (PEG-PBLA) [PDF]
, 2017 Amphiphilic block copolymers, PEG-PBLA with different molecular weights, were synthesized and used as new stabilizers for Itraconazole nannosuspensions (ITZ-PBLA-Nanos).
Cao, Y +9 more
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Preparation, characterization and pharmacokinetics of cyadox nanosuspension
Scientific Reports, 2017 An increase in number of newly developed synthetic drugs displays bioavailability constraints because of poor water solubility. Nanosuspensions formulation may help to overwhelm these problems by increasing dissolution velocity and saturation solubility.
Adeel Sattar +8 more
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