Results 21 to 30 of about 3,529 (130)

Investigating nanoplastics toxicity using advanced stem cell-based intestinal and lung in vitro models

Frontiers in Toxicology, 2023
Plastic particles in the nanometer range–called nanoplastics–are environmental contaminants with growing public health concern. As plastic particles are present in water, soil, air and food, human exposure via intestine and lung is unavoidable, but ...
Mathias Busch, Hugo Brouwer, Germaine Aalderink, Gerrit Bredeck, Angela A. M. Kämpfer, Roel P. F. Schins, Hans Bouwmeester   +6 more
doaj   +1 more source

Development of Microfluidic, Serum-Free Bronchial Epithelial Cells-on-a-Chip to Facilitate a More Realistic In vitro Testing of Nanoplastics

Frontiers in Toxicology, 2021
Most cell culture models are static, but the cellular microenvironment in the body is dynamic. Here, we established a microfluidic-based in vitro model of human bronchial epithelial cells in which cells are stationary, but nutrient supply is dynamic, and
Govind Gupta, Srikanth Vallabani, Romain Bordes, Kunal Bhattacharya, Bengt Fadeel   +4 more
doaj   +1 more source

nanotoxicology

Citation: 'nanotoxicology' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.15908 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms. Requests for commercial
Rosalba Salgado-Morales, Fernando Cuevas-Remigio, Armando Hernández-Mendoza, Gloria Sarahí Castañeda-Ramírez, Gilberto Villa-Rojas, Edgar Dantán-González   +5 more
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An integrated methodology for assessing the impact of food matrix and gastrointestinal effects on the biokinetics and cellular toxicity of ingested engineered nanomaterials

Particle and Fibre Toxicology, 2017
Background Engineered nanomaterials (ENMs) are increasingly added to foods to improve their quality, sensory appeal, safety and shelf-life. Human exposure to these ingested ENMs (iENMS) is inevitable, yet little is known of their hazards.
Glen M. DeLoid, Yanli Wang, Klara Kapronezai, Laura Rubio Lorente, Roujie Zhang, Georgios Pyrgiotakis, Nagarjun V. Konduru, Maria Ericsson, Jason C. White, Roberto De La Torre-Roche, Hang Xiao, David Julian McClements, Philip Demokritou   +12 more
doaj   +1 more source

Implementation of a Dynamic Co-Culture Model Abated Silver Nanoparticle Interactions and Nanotoxicological Outcomes In Vitro

Nanomaterials, 2021
The incorporation of engineered nanoparticles (NPs) into everyday consumer goods, products, and applications has given rise to the field of nanotoxicology, which evaluates the safety of NPs within biological environments.
Nicholas J. Braun, Rachel M. Galaska, Maggie E. Jewett, Kristen A. Krupa   +3 more
doaj   +1 more source

Size- and Oxidation-Dependent Toxicity of Graphene Oxide Nanomaterials in Embryonic Zebrafish

Nanomaterials, 2022
Graphene oxides (GOs) are a popular graphene alternative. The goal of this study was to compare the biocompatibility of a diversity of well-characterized GOs.
Ryan M. Lopez, Joshua R. White, Lisa Truong, Robyn L. Tanguay   +3 more
doaj   +1 more source

The limits of testing particle-mediated oxidative stress in vitro in predicting diverse pathologies; relevance for testing of nanoparticles

Particle and Fibre Toxicology, 2009
In vitro studies with particles are a major staple of particle toxicology, generally used to investigate mechanisms and better understand the molecular events underlying cellular effects. However, there is ethical and financial pressure in nanotoxicology,
Gulumian Mary, Castranova Vincent, Borm Paul JA, Donaldson Ken   +3 more
doaj   +1 more source

Impact of Nanocomposite Combustion Aerosols on A549 Cells and a 3D Airway Model

Nanomaterials, 2021
The use of nanomaterials incorporated into plastic products is increasing steadily. By using nano-scaled filling materials, thermoplastics, such as polyethylene (PE), take advantage of the unique properties of nanomaterials (NM).
Matthias Hufnagel, Nadine May, Johanna Wall, Nadja Wingert, Manuel Garcia-Käufer, Ali Arif, Christof Hübner, Markus Berger, Sonja Mülhopt, Werner Baumann, Frederik Weis, Tobias Krebs, Wolfgang Becker, Richard Gminski, Dieter Stapf, Andrea Hartwig   +15 more
doaj   +1 more source

Exploring electrochemical impedance spectroscopy for the early diagnosis of Mycobacterium tuberculosis using CFP10:ESAT6 protein detection

Frontiers in Sensors
Tuberculosis (TB) was, until SARS-CoV-2 pandemic, the leading cause of death by a single infectious agent contaminating over 10.6 million people with 1.6 million deaths in 2021 worldwide. Herein, we present a proof-of-principle strategy for detecting the
Luisa Vogado Ribeiro, Juliana Cancino-Bernardi, Juliana Cancino-Bernardi, Claudia do Amaral Razzino, Thales Rafael Machado, Marco A. M. Tuesta, Valtencir Zucolotto   +6 more
doaj   +1 more source

Macrophage Polarization Status Impacts Nanoceria Cellular Distribution but Not Its Biotransformation or Ferritin Effects

Nanomaterials, 2023
The innate immune system is the first line of defense against external threats through the initiation and regulation of inflammation. Macrophage differentiation into functional phenotypes influences the fate of nanomaterials taken up by these immune ...
Uschi M. Graham, Alan K. Dozier, David J. Feola, Michael T. Tseng, Robert A. Yokel   +4 more
doaj   +1 more source