Results 121 to 130 of about 21,006 (329)

Nanoarchitectured peroxidase-mimetic nanozymes: mesoporous nanocrystalline alpha- or gamma-iron oxide?

, 2019
Nanozymes (nanoparticles with enzyme-like properties) have attracted considerable attention in recent years owing to their intrinsic enzyme-like properties and broad application in the fields of ELISA based immunoassay and biosensing.
Wood, Kathleen, Alghamidi, Yousef Gamaan, Masud, Mostafa Kamal, Alshehri, Abdulmohsen Ali, Nam-Trung, Nguyen, Adharvanachari, Murugulla, Parsapur, Rajesh Kumar, Hossain, Md Shahriar A, Yamauchi, Yusuke, Selvam, Parasuraman, Kim, Jeonghun, Billah, Md Motasim, Shiddiky, Mohammad JA, Kaneti, Yusuf Valentino, Alzahrani, Khalid Ahmed   +14 more
core   +1 more source

Drought Stress Mediated Changes in Food Crops: Mechanisms and Remediation Strategies

Advanced Science, EarlyView.
This work presents a multi‐scale framework for flavonoid‐mediated drought tolerance in staple food crops, integrating ROS redox regulation, antioxidant defense, rhizosphere microbial interactions, and sustainable agronomic practices. This interdisciplinary model provides core insights to develop climate‐resilient cropping systems and enhance global ...
Xiaoyi Duan, Litao Wang, Tuuli‐Marjaana Koski, Lizhe An, Thomas Efferth, Yujie Fu   +5 more
wiley   +1 more source

Reactive Oxygen Species-Induced Aggregation of Nanozymes for Neuron Injury

, 2019
Nanozymes show excellent enzyme activity and robust catalytic properties, but the targeting capability to disease organs is limited because of lack of specificity.
Hua He (120374), Xinjian Shi (1736347), Qian Wang (32718), Xiaodong Zhang (183379), Fang Huang (154302), Xiaojuan Wang (105141), Daoyong Yu (249993), Baosheng Ge (19061), Junying Wang (509009)   +8 more
core   +1 more source

Disease‐Stage Synchronized Nanozyme Therapy for Polymicrobial Sepsis through Adaptive Catalytic and Immune Reprogramming

Advanced Science, EarlyView.
A disease‐stage synchronized nanozyme platform is developed to treat polymicrobial sepsis by adapting its functions to changing infection environments. The system eliminates multidrug‐resistant bacteria during early infection while reducing inflammation and restoring immune balance during recovery, providing an integrated strategy for infection control
Anlai Zou, Xiaoxue Zhu, Runhan Zhu, Chengchu Xue, Qinyu Zhang, Mengke Li, Ting Yu, Yuzhen Gao, Zhi Ruan, Ying Fu, Yunlei Xianyu, Jun Zhang   +11 more
wiley   +1 more source

TH17–Associated Polyamine Metabolism‐Guided Nanozyme Promotes Alveolar Bone Repair in Periodontitis

Advanced Science, EarlyView.
A pronounced TH17‐skewed immune response is identified in experimental periodontitis, and enrichment of the polyamine pathway is observed during TH17 differentiation, suggesting its potential as an immunometabolic target. Inspired by these findings, DFMO@Ui‐Mn is developed as a therapeutic platform combining cascade ROS scavenging with immunometabolic ...
Cheng Zhu, Tiancheng Li, Yu Jin, Yixin Li, Qicheng Liu, Runzhe Fang, Luyao Qu, Xinyue Tang, Ruomei Li, Xiaoyue Zhao, Jin Hao, Bing Fang, Lunguo Xia   +12 more
wiley   +1 more source

Removing Barriers to Tumor ‘Oxygenation’: Depleting Glutathione Nanozymes in Cancer Therapy

Ruilong Sun,1– 3 Ruitang Liu,1,2 Yongzheng Tian,1 Yunfei Li,1 Bo Fan,1 Songkai Li1 1Spine Surgery, The 940th Hospital of the Joint Logistic Support Force of Chinese People’s Liberation Army, Lanzhou, People’s Republic of China; 2First Clinical Medical ...
Li Y, Li S, Sun R, Tian Y, Liu R, Fan B
core  

Organic Nanozyme‐Embedded Biotherapeutic Thermosensitive Hydrogel for Extracellular GSH Depletion and Postoperative Tumor Suppression

Advanced Science, EarlyView.
A temperature‐sensitive hydrogel loaded with cyanine nanozymes and Escherichia coli is locally injected into postoperative tumor resection beds. Upon light irradiation, synergistic PTT and PDT work with cascaded reactive oxygen species to deplete extracellular GSH, eliminate residual tumor cells, and induce robust antitumor immune responses for ...
Cong Jiang, Zifan Yang, Rong Guo, Meng Suo, Guowei Wang, Dong Chen, Lilin Su, Fuhuan Wang, Shipeng Ning, Kelong Fan, Xuan Wang   +10 more
wiley   +1 more source

Metal–Organic Framework Nanozymes: From Rational Design and Synthesis to Biomedical Applications

Nano-Micro Letters
Highlights This review examines the influence of metal ions and organic ligands on the catalytic activity of metal–organic framework (MOF) nanozymes, thereby providing guidance for the rational design of MOF nanozymes.
Shundong Cai, Mengdie Li, Songyi Wang, Xiaofei Wen, Gang Liu, Chengchao Chu   +5 more
doaj   +1 more source

An Injectable ROS‐Responsive Nanozyme Hydrogel Regulates the Uterine Microenvironment to Prevent Intrauterine Adhesions

Advanced Science, EarlyView.
The injectable CeTA@GPP hydrogel is administered via intrauterine injection, forming a protective barrier. In the high ROS inflammatory microenvironment of injured endometrium, boronate ester cleavage triggers responsive CeTA release and local enrichment.
Peixian Cheng, Jian Song, Yuxin Li, Ming Chen, Zeshen Liang, Binyao Qiu, Xuemin Liu, Xuetao Shi, Yong Fan   +8 more
wiley   +1 more source

Sustainable Ag–Cu bimetallic nanozymes derived from Juglans regia husk exhibit multifunctional catalytic, antimicrobial, and antioxidant activities

Scientific Reports
The rapid emergence of multidrug-resistant microorganisms, oxidative stress, and heavy metal pollution necessitates the development of sustainable and efficient therapeutic agents.
Sona Ayadi Hassan, Leila Rezaei Somee, Parinaz Ghadam, Ahya Abdi Ali   +3 more
doaj   +1 more source