Results 191 to 200 of about 80,245 (335)

Identification of a New Interesting BAG3 Modulator Able to Disrupt Cancer‐Related Pathways

ChemMedChem, Accepted Article.
Continuing our research aimed at discovering new BAG3 modulators as attractive anticancer drug candidates, we performed a screening campaign on an in‐house library, including compounds featuring a large variety of scaffolds. The obtained results induced us to focus on the triazole moiety and, following a stepwise structural refinement of the scaffold ...
Dafne Ruggiero, Eleonora Boccia, Emis Ingenito, Vincenzo Vestuto, Gilda D’Urso, Alessandra Capuano, Agostino Casapullo, Stefania Terracciano, Giuseppe Bifulco, Gianluigi Lauro, Ines Bruno   +10 more
wiley   +1 more source

Visible Light-Promoted Regioselective Benzannulation of Vinyl Sulfoxonium Ylides with Ynoates. [PDF]

JACS Au
Davas DS, Gopalakrishnan DK, Kumar S, Anmol, Karmakar T, Vaitla J.   +5 more
europepmc   +1 more source

Freezing Point Depression of Naphthalene in Sorbed State.

, 1956
Yoshitomo Iwakami
openalex   +2 more sources

Salicylate formation from naphthalene by Pseudomonas aeruginosa [PDF]

, 1968
V. V. Modi, R N Patel
openalex   +1 more source

Inhibition of the Clathrin Terminal Domain—Amphiphysin Protein–Protein Interaction. Probing the Pitstop 2 Aromatic Moiety

ChemMedChem, EarlyView.
Pitstop 2 binds to the clathrin terminal domain. This work explores the nature of the benzylidene moiety, R. The synthesis of 56 novel analogues reveals enhanced potency of a multiple analogues, with catechol‐free 2,3‐dihydroxybenzo[b][1,4]dioxone (54) returning a 1.2 μm IC50, ca 10‐fold more active than Pitstop 2. Pitstop 2, (Z)‐N‐(5‐(4‐bromenzylidene)
Kate Prichard, Mark J Robertson, Ngoc Chau, Jing Xue, Martin Neuenschwander, Uwe Fink, Andre Horatscheck, Marc Nazare, Phillip J Robinson, Volker Haucke, Adam McCluskey   +10 more
wiley   +1 more source

Demonstration of Paneth cell granules using Naphthalene Black.

, 1968
D Bower, C G Chadwin
openalex   +2 more sources

Dearomative syn-Dihydroxylation of Naphthalenes with a Biomimetic Iron Catalyst. [PDF]

J Am Chem Soc
Choukairi Afailal N, Borrell M, Cianfanelli M, Costas M.   +3 more
europepmc   +1 more source

Preparation of Naphthalene-Tamol.

, 1959
Kenji Negoro, Hachiro Hiyama, K. Oshima
openalex   +2 more sources

The Role of Five‐Membered Aromatic Rings Containing N and O in Modulating Bile Acid Receptors: An Overview

ChemMedChem, EarlyView.
Several derivatives incorporating five‐membered aromatic rings are described in this review as bile acid receptor modulators, particularly targeting the farnesoid X receptor and the G protein‐coupled bile acid receptor 1. This review provides a comprehensive analysis of patents and literature that is useful to support researchers in the design of new ...
Claudia Finamore, Carmen Festa, Rosa Barbato, Stefano Fiorucci, Angela Zampella, Simona De Marino   +5 more
wiley   +1 more source

Real-time capture of reactive intermediates in an enzymatic reaction: insights into a P450-catalyzed oxidation. [PDF]

Chem Sci
Pahchan P, Nandy A, Ramireddy E, Banerjee S.   +3 more
europepmc   +1 more source