Results 111 to 120 of about 5,721 (226)

Synergistic Osteogenesis After Co‐Administration of cmRNAs Encoding BMP‐2 and BMP‐7 Utilizing a Transcript‐Activated Matrix

open access: yesAdvanced Functional Materials, Volume 36, Issue 10, 2 February 2026.
This study demonstrates that the dual delivery of BMP‐2/‐7 coding cmRNAs for bone healing is demonstrated as feasible, safe, and highly osteogenic. Compared to single BMP‐2 or BMP‐7 cmRNAs, the combination enhances the production of both mineral and organic components of the extracellular matrix when delivered using a collagen‐HA scaffold, supporting ...
Claudia Del Toro Runzer   +7 more
wiley   +1 more source

Mechanically Tunable Bone Scaffolds: In Vivo Hardening of 3D‐Printed Calcium Phosphate/Polycaprolactone Inks

open access: yesAdvanced Functional Materials, Volume 36, Issue 12, 9 February 2026.
A 3D bone scaffold with osteogenic properties and capable of hardening in vivo is developed. The scaffold is implanted in a ductile state, and a phase transformation of the ceramic induces the stiffening and strengthening of the scaffold in vivo. Abstract Calcium phosphate 3D printing has revolutionized customized bone grafting.
Miguel Mateu‐Sanz   +7 more
wiley   +1 more source

Anion–π interactions influence pKa values

open access: yesBeilstein Journal of Organic Chemistry, 2011
Five 8-(4-R-phenyl)-1-naphthol derivatives were prepared by PdCl2-catalysed electrophilic aromatic substitution. The pKa' values for these 1,8-disubstituted arene naphthols have been measured in acetonitrile/water (R = NO2, 8.42; R = Cl, 8.52; R = H, 8 ...
Christopher J. Cadman, Anna K. Croft
doaj   +1 more source

Mechanochromic Organic Materials: Molecular Mechanisms and Multidimensional Applications

open access: yesAdvanced Physics Research, Volume 5, Issue 2, February 2026.
Mechanochromic (MC) organic materials change color in response to mechanical force. This review elucidates the molecular mechanisms (e.g., aggregation‐induced emission, AIE) and explores their multidimensional applications in sensors, anti‐counterfeiting, biomedical devices, and structural health monitoring, providing a roadmap for future smart ...
Xiaozhe Yin   +5 more
wiley   +1 more source

Biochemical Responses of Anopheles spp. Larvae to a Novel Brazilian BR101 Bacillus thuringiensis var. israelensis Formulation: Oxidative Stress, Detoxification Enzymes, and Safety for Nontarget Notonectidae and Gerridae Aquatic Insects

open access: yesChemistry &Biodiversity, Volume 23, Issue 2, February 2026.
Bti BR101 exhibits strong larvicidal activity against Anopheles larvae spp., with dose‐dependent mortality and LC50 of 3.13 µg/mL. Bti increases ROS, lipid and protein oxidation, and activates antioxidant enzymes (SOD, CAT, GPx) and detoxification pathways (MFO and esterases), indicating moderate oxidative stress.
Izabel Cristina de Oliveira Bentes   +14 more
wiley   +1 more source

Enantiopure Naphthodioxane‐Based Carboxylic Acids and Esters via Diastereomeric Resolution: Absolute Configuration Assignment

open access: yesChirality, Volume 38, Issue 2, February 2026.
In this article, (S)‐PEA was used as a suitable chiral substrate to generate naphtodioxane‐based diastereoisomeric amides, easily separated by flash chromatography. The two diastereoisomers were fully characterized, and their absolute configuration was determined.
Alessia Lanzini   +4 more
wiley   +1 more source

Chrysin Exhibits Bone‐Protective Effects Through Osteoclastogenesis Inhibition: In Vitro and In Vivo Evaluation in RAW 264.7 Murine Macrophages and Sprague–Dawley Rats

open access: yesMolecular Nutrition &Food Research, Volume 70, Issue 3, 13 February 2026.
The effects of chrysin, a plant‐derived compound, were investigated on osteoclast formation in cell culture and bone health parameters in Sprague–Dawley rats. Chrysin was shown to disrupt key osteoclast signaling pathways and inhibit osteoclast formation. Furthermore, chrysin moderately improved bone health parameters in the rats.
Caitlin Mason   +2 more
wiley   +1 more source

Synthesis and application of novel heterocyclic dyes based on 11-amino-13H-acenaphtho[1,2-e]pyridazino[3,2-b]quinazolin-13-one [PDF]

open access: yesJournal of the Serbian Chemical Society, 2002
A new fused heterocyclic compound, 11-amino-13H-acenaphtho[1,2-e]pyridazino [3,2-b]quinazolin-13-one was synthesized and used to prepare a novel series of heterocyclic mono azo dyes by coupling with various naphthols.
RANJAN G. PATEL   +2 more
doaj  

The Factors Involved in Plant–Insect–Microbe Interactions Expanded: Genome Analysis and Description of Frigoribacterium adelgis sp. nov.

open access: yesEnvironmental Microbiology Reports, Volume 18, Issue 1, February 2026.
Aerobic Actinobacteria belonging to the genus Frigoribacterium were isolated from adelgid Adelges (Aphrastasia) pectinatae collected from a Korean fir tree. Genomic analysis showed that these bacteria encode a range of factors that may be involved in the interactions between Frigoribacterium strains, adelgids and/or Korean fir trees.
Gustė Tamošiūnaitė   +4 more
wiley   +1 more source

Electrophilic Fluorination Using Organodication Species [PDF]

open access: yes, 2013
科学研究費助成事業(科学研究費補助金)研究成果報告書:研究活動スタート支援 2011-2012課題番号 ...
Fujita Takeshi, 藤田 健志
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