Results 141 to 150 of about 4,751 (182)

Luciferase inhibition by a novel naphthoquinone

Journal of Photochemistry and Photobiology B: Biology, 2012
The novel naphthoquinone 12,13-dihydro-N-methyl-6,11,13-trioxo-5H-benzo[4,5]cyclohepta[1,2-b]naphthalen-5,12-imine (hereafter called TU100) was created as a potential chemotherapeutic agent. Previous work showed it is an irreversible inhibitor of type I and II topoisomerases that alkylates specific enzyme thiols.
Bedford, Rebecca, LePage, Daniel, Hoffmann, Rachel, Kennedy, Steven, Gutschenritter, Tyler, Bull, Lauran, Sujijantarat, Nanthiya, DiCesare, John C., Sheaff, Robert J.   +8 more
openaire   +3 more sources

A spiro-linked pyrene–naphthoquinone

Acta Crystallographica Section C Crystal Structure Communications, 2000
The title molecule, 2'-pyrenylspiro[2, 3-dihydro-1H-cyclopenta[b]naphthalene-2,5'-1',3'-dioxane]-4,9-dione, C(32)H(22)O(4), contains an electron-donating pyrene group spiro-linked to an electron-accepting naphthoquinone. The molecules are V-shaped in profile and stack to form columns along b with alternating, approximately coplanar, pyrene and ...
J A, Potenza, T J, Emge, J, Albaneze, S, Knapp, H J, Schugar   +4 more
openaire   +2 more sources

Reactions of 1,4-naphthoquinone and 5-hydroxy-1,4-naphthoquinone with ninhydrin

Russian Chemical Bulletin, 2019
1,4-Naphthoquinone and 5-hydroxy-1,4-naphthoquinone react with ninhydrin to give 2-(2-hydroxy-1,3-dioxo-2,3-dihydro-1H-inden-2-yl)naphthalene-1,4-dione and 8-hydroxy- 2-(2-hydroxy-1,3-dioxo-2,3-dihydro-1H-inden-2-yl)naphthalene-1,4-dione, respectively.
L. M. Gornostaev, O. I. Fominyh, T. I. Lavrikova, Yu. G. Khalyavina, Yu. V. Gatilov, G. A. Stashina   +5 more
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In Vitro Cytotoxicities of 1,4‐Naphthoquinone and Hydroxylated 1,4‐Naphthoquinones to Replicating Cells

Journal of Applied Toxicology, 1993
AbstractUsing the human hepatoma cell line, HepG2, and the BALB/c mouse fibroblast cell line, 3T3, as the bioindicators in the neutral red cytotoxicity assay, the effect of hydroxyl substitution on the toxicity of 1,4‐naphthoquinone was studied.
H, Babich, A, Stern
openaire   +2 more sources

Oxidative Aminotrifluoromethylation of 1,4-Naphthoquinone

The Journal of Organic Chemistry
A strategy for convenient and precise oxidative aminotrifluoromethylation of 1,4-naphthoquinone with the Togni reagent and amines has been demonstrated via a radical process. This method allows efficient access for the preparation of a wide range of CF3-functionalized 1,4-naphthoquinones under mild conditions, and its application in late-stage ...
Lin Tang, Fengjuan Jia, Ruijun Yu, Xinmeng Wei, Lufang Zhang, Ge Lv, Qiuju Zhou   +6 more
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Naphthoquinone derivatives from SPP.: bisisodiospyrin, a tetrameric naphthoquinone

Tetrahedron Letters, 1970
K. Yoshihira, Michiko Tezuka, S. Natori
openaire   +1 more source

Naphthoquinones

2000
Johann Grolig, Rudolf Wagner
openaire   +1 more source

Naphthoquinone Antimalarials. XIV. 2-Hydroxy-3-aryl-1,4-naphthoquinones

Journal of the American Chemical Society, 1948
H E, ZAUGG, R T, RAPALA, M T, LEFFLER
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NAPHTHOQUINONE OXIDES

Journal of the American Chemical Society, 1940
L. F. Fieser, M. Tishler, W. L. Sampson
openaire   +1 more source

Naphthoquinone series

Proceedings of the Indian Academy of Sciences - Section A, 1954
B. Suryanarayana, B. D. Tilak
openaire   +1 more source