Results 161 to 170 of about 7,497 (214)

Aromaticity recovery as a driving force for electron transfer and radical addition in 5-hydroxy-1,4-naphthoquinone derivatives. [PDF]

RSC Adv
My Hao NT, Dieu Ly LT, Thanh PN, Le Huyen T, Vo QV, Ngo ST, Thong NM, Huong DQ, Nam PC.   +8 more
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De novo synthesis of plant polyketide plumbagin in yeast: a platform for sustainable production of naphthoquinones. [PDF]

Nat Prod Bioprospect
Vasav AP, Barvkar VT.
europepmc   +1 more source

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Naphthoquinone metabolites of the fungi

Phytochemistry, 1998
Structures and physico-chemical properties of 100 naphthoquinone metabolites produced by filamentous fungi are reviewed. The conditions of pigment formation, biogenesis and the mechanism of biosynthesis of pigments by fungi are described. Sixty-three fungi cultures able to produce naphthoquinone are listed.
A G, Medentsev, V K, Akimenko
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Dihydroxyacetone Naphthoquinone Sunscreen

JAMA: The Journal of the American Medical Association, 1972
To the Editor.— During the past decade, we have successfully used a sunscreen containing dihydroxyacetone/ naphthoquinone (lawsone) for patients with all types of cutaneous photosensitivity. 1 An advantage of this sunscreen is its capacity to induce a broad "ultraviolet shield" (290 to 405 nm) in the uppermost layer of the skin.
R M, Fusaro, J A, Johnson
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Iodinated 1,4-naphthoquinones

Russian Chemical Bulletin, 2005
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
N. V. Ivashkina, E. A. Yakovleva, I. D. Ivanchikova, A. A. Moroz, M. S. Shvartsberg   +4 more
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Potent antitumor activity of synthetic 1,2-Naphthoquinones and 1,4-Naphthoquinones

Bioorganic & Medicinal Chemistry, 2003
Rhinacanthone (1) and two 1,2-pyranonaphthoquinones (2,3) were synthesized and found to show very potent cytotoxicity against three cancer cell lines (KB, HeLa and HepG(2)) with IC(50) values of 0.92-9.63 microM, whereas the corresponding hydroxylated derivative 4 had reduced cytotoxicity (IC(50) values of 7.61-24.13 microM).
Ngampong, Kongkathip, Boonsong, Kongkathip, Pongpun, Siripong, Chak, Sangma, Suwaporn, Luangkamin, Momad, Niyomdecha, Suppachai, Pattanapa, Suratsawadee, Piyaviriyagul, Palangpon, Kongsaeree   +8 more
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Organocatalytic atroposelective synthesis of naphthoquinone thioglycosides from aryl-naphthoquinones and thiosugars

Chemical Communications, 2023
A stereoselective organocatalytic strategy was developed to synthesize the axially chiral naphthoquinone thioglycosides from aryl-naphthoquinones and thiosugars. The reaction pathway involves atroposelective addition and stereoretentive oxidation.
Yuling Wu, Wu-Jingyun Zhou, Laiping Yao, Yadi Niu, Hongli Zhao, Cheng Peng, Bo Han, Wei Huang, Gu Zhan   +8 more
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Naphthoquinone Derivatives Targeting Melanoma

Current Topics in Medicinal Chemistry, 2023
Abstract: Cancer is responsible for high mortality rates worldwide, representing a serious health problem. In this sense, melanoma corresponds to the most aggressive type of skin cancer, being the cause of the highest death rates. Therapeutic strategies for the treatment of melanoma remain limited, with problems associated with toxicity, serious side ...
Jéssica Alves Nunes, Adrielle Firmino da Silva Nunes, Dimas José da Paz Lima, Edeildo Ferreira da Silva-Júnior   +3 more
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1,4-Naphthoquinone

2001
[130-15-4] C10H6O2 (MW 158.16) InChI = 1S/C10H6O2/c11-9-5-6-10(12)8-4-2-1-3-7(8)9/h1-6H InChIKey = FRASJONUBLZVQX-UHFFFAOYSA-N (dienophile used to synthesize various aromatic rings via Diels–Alder or cycloaddition-type reactions;1 undergoes amination,2 allylation,3 cyclooligomerization,4 and Thiele–Winter acetoxylation to give ...
Erica Caldwell, Laurent Deloux, Morris Srebnik   +2 more
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Luciferase inhibition by a novel naphthoquinone

Journal of Photochemistry and Photobiology B: Biology, 2012
The novel naphthoquinone 12,13-dihydro-N-methyl-6,11,13-trioxo-5H-benzo[4,5]cyclohepta[1,2-b]naphthalen-5,12-imine (hereafter called TU100) was created as a potential chemotherapeutic agent. Previous work showed it is an irreversible inhibitor of type I and II topoisomerases that alkylates specific enzyme thiols.
Bedford, Rebecca, LePage, Daniel, Hoffmann, Rachel, Kennedy, Steven, Gutschenritter, Tyler, Bull, Lauran, Sujijantarat, Nanthiya, DiCesare, John C., Sheaff, Robert J.   +8 more
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